1. IntroductionHumans have the ability (or competence) to think logically, and this is an undeniable fact. However,what this ability consists in is a difficult question. It might be said that logical ability consists ...1. IntroductionHumans have the ability (or competence) to think logically, and this is an undeniable fact. However,what this ability consists in is a difficult question. It might be said that logical ability consists in theknowledge of a set of logic rules. But what are those logic rules? For centuries logicians have devel-展开更多
Digital media offer unique opportunities for museums to bring to life the secrets and stories of their historical collections.To bring insight into the process of developing digital media exhibits,this paper presents ...Digital media offer unique opportunities for museums to bring to life the secrets and stories of their historical collections.To bring insight into the process of developing digital media exhibits,this paper presents the perspective of a creative practitioner in approaching technology-and media-based interpretation for collection objects.It follows the Time,Culture and Identity digital workshop held in Beijing in October 2019,which explored and shared ideas about collaborative research and interdisciplinary practice in digital interpretation between academics,institutions,creative practitioners,and developers.Following the direction of the workshop,the paper takes as its focus the clocks and automatons of the imperial collection at the Palace Museum in Beijing.Observations are based on the author’s practice-led experience in running a design studio,Harmonic Kinetic,developing new media exhibits using digital technology and audiovisual media for museums,galleries,and exhibitions in the UK,including the Science Museum,V&A,Barbican,Tate,and the Tower of London.Taking a broad interaction-design-led outlook,the paper explores a personal design perspective for developing interpretive content and considers the particular opportunities and approaches these historical devices suggest.The paper concludes with a final section that reviews the process and reflects on outcomes from the Time,Culture and Identity digital workshop.This explored possibilities for an interpretive exhibit on the Country Scene clock from the Palace Museum collection.展开更多
Importance:Drug-likeness of a compound is an overall assessment of its potential to succeed in clinical trials,and is essential for economizing research expenditures by filtering compounds with unfavorable properties ...Importance:Drug-likeness of a compound is an overall assessment of its potential to succeed in clinical trials,and is essential for economizing research expenditures by filtering compounds with unfavorable properties and poor development potential.To this end,a robust drug-likeness prediction method is indispensable.Various approaches,including discriminative rules,statistical models,and machine learning models,have been developed to predict drug-likeness based on physiochemical properties and structural features.Notably,recent advancements in novel deep learning techniques have significantly advanced drug-likeness prediction,especially in classification performance.Highlights:In this review,we addressed the evolving landscape of drug-likeness prediction,with emphasis on methods employing novel deep learning techniques,and highlighted the current challenges in drug-likeness prediction,specifically regarding the aspects of generalization and interpretability.Moreover,we explored potential remedies and outlined promising avenues for future research.Conclusion:Despite the hurdles of generalization and interpretability,novel deep learning techniques have great potential in drug-likeness prediction and are worthy of further research efforts.展开更多
The relationship between the sexes and the female condition are underlying motifs in Gao Xingjian＇s post-exile plays, yet very few scholarly studies of his work have focused solely on the analysis of gender in his pl...The relationship between the sexes and the female condition are underlying motifs in Gao Xingjian＇s post-exile plays, yet very few scholarly studies of his work have focused solely on the analysis of gender in his plays. In those studies that have, most have directed their attention toward Gao＇s novels, and many scholars have come to regard Gao as a misogynist writer. This paper examines Gao＇s attitude toward gender through an analysis of his plays, specifically Between Life and Death （Shengsijie, 1991）. The theatrical medium illustrates a more complex elaboration of gender representation than those seen in Gao＇s novels---one that complicates conceptions of the writer＇s misogyny. Focusing on Between Life and Death, I assert that Gao＇s alleged misogyny is a misrepresentation. Regarding my theoretical approach, I make particular reference to feminist theorists such as Julia K_dsteva and Judith Butler. The debate is linked to Gao＇s concept of an un-gendered/originary self and considers the use of dramatic devices--specifically focusing on the use of tripartition.展开更多
文摘1. IntroductionHumans have the ability (or competence) to think logically, and this is an undeniable fact. However,what this ability consists in is a difficult question. It might be said that logical ability consists in theknowledge of a set of logic rules. But what are those logic rules? For centuries logicians have devel-
文摘Digital media offer unique opportunities for museums to bring to life the secrets and stories of their historical collections.To bring insight into the process of developing digital media exhibits,this paper presents the perspective of a creative practitioner in approaching technology-and media-based interpretation for collection objects.It follows the Time,Culture and Identity digital workshop held in Beijing in October 2019,which explored and shared ideas about collaborative research and interdisciplinary practice in digital interpretation between academics,institutions,creative practitioners,and developers.Following the direction of the workshop,the paper takes as its focus the clocks and automatons of the imperial collection at the Palace Museum in Beijing.Observations are based on the author’s practice-led experience in running a design studio,Harmonic Kinetic,developing new media exhibits using digital technology and audiovisual media for museums,galleries,and exhibitions in the UK,including the Science Museum,V&A,Barbican,Tate,and the Tower of London.Taking a broad interaction-design-led outlook,the paper explores a personal design perspective for developing interpretive content and considers the particular opportunities and approaches these historical devices suggest.The paper concludes with a final section that reviews the process and reflects on outcomes from the Time,Culture and Identity digital workshop.This explored possibilities for an interpretive exhibit on the Country Scene clock from the Palace Museum collection.
文摘Importance:Drug-likeness of a compound is an overall assessment of its potential to succeed in clinical trials,and is essential for economizing research expenditures by filtering compounds with unfavorable properties and poor development potential.To this end,a robust drug-likeness prediction method is indispensable.Various approaches,including discriminative rules,statistical models,and machine learning models,have been developed to predict drug-likeness based on physiochemical properties and structural features.Notably,recent advancements in novel deep learning techniques have significantly advanced drug-likeness prediction,especially in classification performance.Highlights:In this review,we addressed the evolving landscape of drug-likeness prediction,with emphasis on methods employing novel deep learning techniques,and highlighted the current challenges in drug-likeness prediction,specifically regarding the aspects of generalization and interpretability.Moreover,we explored potential remedies and outlined promising avenues for future research.Conclusion:Despite the hurdles of generalization and interpretability,novel deep learning techniques have great potential in drug-likeness prediction and are worthy of further research efforts.
文摘The relationship between the sexes and the female condition are underlying motifs in Gao Xingjian＇s post-exile plays, yet very few scholarly studies of his work have focused solely on the analysis of gender in his plays. In those studies that have, most have directed their attention toward Gao＇s novels, and many scholars have come to regard Gao as a misogynist writer. This paper examines Gao＇s attitude toward gender through an analysis of his plays, specifically Between Life and Death （Shengsijie, 1991）. The theatrical medium illustrates a more complex elaboration of gender representation than those seen in Gao＇s novels---one that complicates conceptions of the writer＇s misogyny. Focusing on Between Life and Death, I assert that Gao＇s alleged misogyny is a misrepresentation. Regarding my theoretical approach, I make particular reference to feminist theorists such as Julia K_dsteva and Judith Butler. The debate is linked to Gao＇s concept of an un-gendered/originary self and considers the use of dramatic devices--specifically focusing on the use of tripartition.
