To the Editor:Many well-studied sonographic features have been used clinically to evaluate thyroid nodules for malignancies.Sonographic grayscale features proposed by the American College of Radiology Thyroid Imaging,...To the Editor:Many well-studied sonographic features have been used clinically to evaluate thyroid nodules for malignancies.Sonographic grayscale features proposed by the American College of Radiology Thyroid Imaging,Reporting and Data System(TI-RADS)include composition,echogenicity,shape,margin,and echogenic foci.[1]Other features,such as vascularity imaging,have gradually been recognized by sonographers.Sustained angiogenesis results in tumor-specific vasculature compared to normal tissues in the context of architecture and biological behavior.[2]Tumor neovascularization shows abnormal maturation,manifesting irregular sprouting,and branching of angiogenic vessels with disordered coverage of pericytes.Therefore,vascularity is critical for the evaluation of malignancy in thyroid nodules.展开更多
基金a grant from the Natural Science Foundation of Liaoning Province(No.201602221)。
文摘To the Editor:Many well-studied sonographic features have been used clinically to evaluate thyroid nodules for malignancies.Sonographic grayscale features proposed by the American College of Radiology Thyroid Imaging,Reporting and Data System(TI-RADS)include composition,echogenicity,shape,margin,and echogenic foci.[1]Other features,such as vascularity imaging,have gradually been recognized by sonographers.Sustained angiogenesis results in tumor-specific vasculature compared to normal tissues in the context of architecture and biological behavior.[2]Tumor neovascularization shows abnormal maturation,manifesting irregular sprouting,and branching of angiogenic vessels with disordered coverage of pericytes.Therefore,vascularity is critical for the evaluation of malignancy in thyroid nodules.
