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Quantification of Ride Comfort Using Musculoskeletal Mathematical Model Considering Vehicle Behavior
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作者 Junya Tanehashi Szuchi Chang +4 位作者 Takahiro Hirosei Masaki Izawa Aman Goyal Ayumi Takahashi Kazuhito Misaji 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第6期2287-2306,共20页
This research aims to quantify driver ride comfort due to changes in damper characteristics between comfort mode and sport mode,considering the vehicle’s inertial behavior.The comfort of riding in an automobile has b... This research aims to quantify driver ride comfort due to changes in damper characteristics between comfort mode and sport mode,considering the vehicle’s inertial behavior.The comfort of riding in an automobile has been evaluated in recent years on the basis of a subjective sensory evaluation given by the driver.However,reflecting driving sensations in design work to improve ride comfort is abstract in nature and difficult to express theoretically.Therefore,we evaluated the human body’s effects while driving scientifically by quantifying the driver’s behavior while operating the steering wheel and the behavior of the automobile while in motion using physical quantities.To this end,we collected driver and vehicle data using amotion capture system and vehicle CAN and IMU sensors.We also constructed a three-dimensional musculoskeletal mathematical model to simulate driver movements and calculate the power and amount of energy per unit of time used for driving the joints and muscles of the human body.Here,we used comfort mode and sport mode to compare damper characteristics in terms of hardness.In comfort mode,damper characteristics are soft and steering stability is mild,but vibration from the road is not easily transmitted to the driver making for a lighter load on the driver.In sport mode,on the other hand,damper characteristics are hard and steering stability is comparatively better.Still,vibration from the road is easily transmitted to the driver,whichmakes it easy for a load to be placed on the driver.As a result of this comparison,it was found that a load was most likely to be applied to the driver’s neck.This result in relation to the neck joint can therefore be treated as an objective measure for quantifying ride comfort. 展开更多
关键词 Human engineering BIOMECHANICS driver’s sense of fatigue double lane change musculoskeletal mathematical model
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Performance Evaluation of Electromagnetic Shield Constructed from Open-Cell Metal Foam Based on Sphere Functions
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作者 Yuya Hanaoka Taku Itoh +2 位作者 Kohei Tateyama Susumu Nakata Keiko Watanabe 《Computer Modeling in Engineering & Sciences》 SCIE EI 2022年第7期43-53,共11页
This study evaluates the performance of a model of open-cell metal foams generated by sphere functions.To this end,an electromagnetic shield constructed from the model was inserted between two horn antennas in an elec... This study evaluates the performance of a model of open-cell metal foams generated by sphere functions.To this end,an electromagnetic shield constructed from the model was inserted between two horn antennas in an electromagnetic wave propagation simulation.The foam-hole diameter in the electromagnetic shield model was varied as d=2.5 and 5.0 mm,and the frequency of the electromagnetic waves was varied from 3 to 13 GHz.In the numerical experiments of shield effectiveness,the shields with foam holes of both diameters attenuated the electromagnetic waves across the studied frequency range.The shield effectiveness was enhanced at low frequencies and in the shield with smaller hole diameter. 展开更多
关键词 Electromagnetic propagation electromagnetic shielding materials metal foams numerical simulation
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Expression of Acetaldehyde Dehydrogenase Gene Increases Hydrogen Production and Acetate Consumption by <i>Rhodobacter sphaeroides</i>
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作者 Shinya Hasegawa Jyumpei Kobayashi +2 位作者 Tomoe Komoriya Hideki Kohno Kazuaki Yoshimune 《Energy and Power Engineering》 2015年第9期396-402,共7页
Rhodobacter sphaeroides RV (RV) produces high yields of hydrogen from organic acids in the presence of light. The hydrogen production from acetate is lower than that from lactate, probably because of its low ability t... Rhodobacter sphaeroides RV (RV) produces high yields of hydrogen from organic acids in the presence of light. The hydrogen production from acetate is lower than that from lactate, probably because of its low ability to metabolize acetate. In this study, gene of acetaldehyde dehydrogenase (ACDH, EC 1.2.1.10) that catalyzes the reversible conversion of acetaldehyde and CoA to acetyl-CoA with the concurrent reduction of NAD to NADH, is overexpressed in the RV strain. The produced acetyl-CoA can be oxidized to carbon dioxide in the tricarboxylic acid (TCA) cycle, wherein electrons are generated and used for hydrogen production. The byproduct NADH can be used as reducing agent for acetate to produce acetaldehyde by acetate dehydrogenase. The recombinant RV strain (RVAC) expressing the ACDH gene showed ACDH activity with a specific activity of 3.2 mU/ mg, and the RV and the recombinant RV strain that harbored the intact (empty) plasmid pLP-1.2 (RVI) showed no detectable ACDH activity. The hydrogen yields of the RVAC strain from 21-mM acetate were 1.5-fold higher than that of the wild type RV strain and also that of the RVI strain. In contrast, hydrogen yield from 21-mM lactate was 30% lower than that in the control strains. 展开更多
关键词 ACETATE LACTATE Photosynthetic Bacteria RHODOBACTER SPHAEROIDES Aldehyde Dehydrogenase
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Optical and Electrochemical Properties of Non-Peripheral Thioaryl-Substituted Subphthalocyanine as Precursors for Dye-Sensitizer to Develop Photovoltaic Cells
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作者 Keiichi Sakamoto Satoru Yoshino +5 位作者 Makoto Takemoto Kazuhiro Sugaya Hitomi Kubo Tomoe Komoriya Shinnosuke Kamei Shigeki Furukawa 《American Journal of Analytical Chemistry》 2014年第15期1037-1045,共9页
Phthalocyanines-related compounds, subphthalocyanines, are the homologues consisting of three isoindole units with boron as the center. The absorption maximum of subphthalocyanines, called the Q band, appears around 5... Phthalocyanines-related compounds, subphthalocyanines, are the homologues consisting of three isoindole units with boron as the center. The absorption maximum of subphthalocyanines, called the Q band, appears around 560 - 630 nm, which is shifted by approximately 100 nm to shorter wavelengths compared to phthalocyanines. Subphthalocyanines are used as precursors to prepare unsymmetric phthalocyanines for ring enlargement reaction. In this decade, phthalocyanines are used for dye-sensitized solar cells (DSSCs), which require strong absorption of far-red light between 700 and 850 nm because of their highly efficiency. Non-peripheral thioaryl-substituted phthalocyanines have been synthesized. They show near-infrared absorption around 780 - 870 nm and have excellent electron transfer properties. However, their lack of affinity to basal plats inhibits their use as DSSC photosensitizer. Therefore, to synthesize unsymmetrical non-peripheral thioaryl-substituted phthalocyanines possessing good affinity to basal plates, the authors prepared subphthalocyanines having thioaryl substituents as precursors. Spectroscopic properties and electron transfer abilities to synthesize non-peripheral thioaryl-substituted subphthalocyanines were estimated using cyclic voltammetry. The Q band of non-peripheral thioaryl-substituted subphthalocyanines shows around 650 nm shifted to longer wavelength by 86 nm in comparison to subphthalocyanine. The compounds show many reduction potentials. They are acceptable electrons in the subphthalocyanine ring, meaning that the compounds have good electron transfer properties. 展开更多
关键词 Thioaryl SUBSTITUENTS Phthalocyanines SUBPHTHALOCYANINE Cyclic VOLTAMMETRY Precursor for Dye-Sensitizer
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Combination of specific monoclonal antibodies allow identification of soluble aggregates of by sandwich ELISA
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作者 Takenori Shimizu Kazuaki Yoshimune +3 位作者 Tomoe Komoriya Takahiro Akiyama Xujun Ye Hideki Kohno 《Advances in Bioscience and Biotechnology》 2013年第4期63-66,共4页
Aggregate amyloid beta protein1-42 (Aβ1-42) can typically be found in the early stage of Alzheimer’s disease (AD). Aβ1-42 self-assembles and is highly toxic to neurons. Thus, recognizing aggregated Aβ1-42 is very ... Aggregate amyloid beta protein1-42 (Aβ1-42) can typically be found in the early stage of Alzheimer’s disease (AD). Aβ1-42 self-assembles and is highly toxic to neurons. Thus, recognizing aggregated Aβ1-42 is very important for elucidation of Aβ1-42 structure and for the diagnosis of AD. In this study, the specificity of the 79-3 monoclonal antibody against soluble aggre- gate Aβ1-42 was measured by sandwich Enzyme-Linked Immuno Sorbent Assay (ELISA). Eight monoclonal antibodies against both soluble aggregates and amorphous aggregates were used as primary antibodies. Soluble aggregates and amorphous aggregates were used as antigen. As secondary antibody, HRP was labeled with the 79-3 monoclonal antibody. The reactivity of the 79-3 monoclonal antibody against soluble aggregates was confirmed in all combinations, but little reactivity against amorphous aggregates was found. Furthermore, we performed the above sandwich ELISA using the 37-11 antibody, which is reactive against large oval aggregates (LOA) that occur in micro aggregates, instead of the 79-3 antibody. The 77-3 antibody is 1 of the 8 monoclonal antibodies against soluble aggregates;amorphous aggregates also reacted with the 37-11 antibody. These results indicated that soluble aggregates are specifically recognized by a combination of different antibodies. The combined use of these antibodies can be applied to the diagnosis of AD and to defining the structure of the Aβ1-42. 展开更多
关键词 AΒ1-42 MONOCLONAL Antibody SOLUBLE AGGREGATES ELISA
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Copper Ions Enhance Signal Intensity of Sandwich ELISA for Amorphous Aggregates of Amyloid-β42
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作者 Akira Itakura Yoshio F. Kanematsu +2 位作者 Ryoko Suzuki Hideki Kohno Kazuaki Yoshimune 《Advances in Bioscience and Biotechnology》 2016年第9期343-349,共7页
Amyloid-β<sub>42</sub> (Aβ<sub>42</sub>) accumulates within senileplaque, a pathological hall mark of Alzheimer’s disease (AD). Our previous reports showed that the monoclonal antibodies 37-... Amyloid-β<sub>42</sub> (Aβ<sub>42</sub>) accumulates within senileplaque, a pathological hall mark of Alzheimer’s disease (AD). Our previous reports showed that the monoclonal antibodies 37-11 and 77-3 react with conformational epitopes on the surface of the soluble aggregates of Aβ<sub>42</sub> and that sandwich ELISA using these two monoclonal antibodies yields high reactivity to detect soluble aggregates of Aβ<sub>42</sub>. Here, the reactivity of the sandwich ELISA was shown to increase in the presence of 50 μM Cu<sup>2+</sup>. However, the addition of Cu<sup>2+</sup> had only a small effect on the reactivity of a direct ELISA using antibody 37-11 or 77-3, suggesting that Cu<sup>2+</sup> has a small effect on the number of epitopes on the surface of the aggregates. Atomic force microscopy images showed that larger aggregates were formed in the presence of Cu<sup>2+</sup>, as shown in the other reports. Cu<sup>2+</sup> may gather the aggregates with distinct epitopes recognized by antibodies 37-11 and 77-3, leading to increased signal intensity of the sandwich ELISA. 展开更多
关键词 Amyloid-β42 Soluble Aggregates ANTIBODY ELISA
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TRISim:A Triage Simulation System to Exploit and Assess Triage Operations for Hospital Managers-Development,Validation and Experiment
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作者 A.Koba yashi K.Suginuma M.Furui chi 《Computer Modeling in Engineering & Sciences》 SCIE EI 2017年第2期117-149,共33页
Triage is a method for determining the priority of patients’treatment to improve survival rates.Different triage methods are used in hospitals,and they are applied after performing an evaluation based on standard met... Triage is a method for determining the priority of patients’treatment to improve survival rates.Different triage methods are used in hospitals,and they are applied after performing an evaluation based on standard methods such as the Japan Triage Acuity Scale(JTAS)or Emergency Severity Index(ESI).It is important to consider the characteristics of all the hospitals when assigning triage methods and emergency levels to them;the hospital managers make these decisions.We propose a multi-agent simulation method to support the hospital managers in employing the triage protocols according to their environment.We developed a prototype simulation system called TRISim to explore and assess the triage operations.In this paper,we provide an overview of TRISim and present our experimental results to validate the system. 展开更多
关键词 Multi-agent SIMULATION MAS TRIAGE SIMULATION JTAS ESI MTS emergency DEPARTMENT
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基于镰仓时期区域可视化模型研究当地居民景观识别的构成(英文)
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作者 山田悟史 新谷伸高 大内宏友 《华南理工大学学报(自然科学版)》 EI CAS CSCD 北大核心 2007年第B10期209-212,共4页
研究了镰仓历史街区的景观识别.构成区域环境的城市结构以三维因子分析来进行量化分析,此3项因子为:三维的阴影图、航拍图和立体模型.景观识别与可视的区域景象和区域认知图相关.通过对典型的镰仓景观的分形维数分析,试图揭示居民对实... 研究了镰仓历史街区的景观识别.构成区域环境的城市结构以三维因子分析来进行量化分析,此3项因子为:三维的阴影图、航拍图和立体模型.景观识别与可视的区域景象和区域认知图相关.通过对典型的镰仓景观的分形维数分析,试图揭示居民对实体或环境变化的共同观察,同时考虑了居民对其观察的确认及其与城市结构的关系. 展开更多
关键词 景观识别 分形 航拍 视觉 空间 居民
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教育环境与儿童空间认知的城镇空间组成研究(英文)
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作者 大内節子 山田悟史 大内宏友 《华南理工大学学报(自然科学版)》 EI CAS CSCD 北大核心 2007年第B10期205-208,共4页
文中从发展对儿童适宜的生活环境的观点出发来研究城市住房项目.该项研究是针对Makahari湾城镇的中层住宅及附属教育设施的公寓区展开的.文中采用草图来确定Makahari湾城镇中儿童生活与其环境之间的关系.1999年进行首次研究,接着在2003... 文中从发展对儿童适宜的生活环境的观点出发来研究城市住房项目.该项研究是针对Makahari湾城镇的中层住宅及附属教育设施的公寓区展开的.文中采用草图来确定Makahari湾城镇中儿童生活与其环境之间的关系.1999年进行首次研究,接着在2003年进行第二次研究,此间该镇的建设有所发展.具体研究是利用儿童凭记忆点出的关于他们的住宅、学校、玩耍场地和其它较多被注意的场所的草图来进行的.在两次研究期间,该地区发生了许多实体环境的变化,这些变化能从儿童的草图的许多元素中反映出来.将这些草图中的变化加以对照、分析,并将环境的改变与儿童的空间认知的关系加以探讨,同时注意分析比较体现在草图中的区域范围.结果表明,儿童早期对目标物的了解能从Makahari湾的空间结构以及环境变化中得到增强,而两者都由方格的模式构成.经验、每日的生活以及对小学和儿童游戏场所的空间认知与儿童的生活环境息息相关.此项分析揭示了在一个发展中的住宅区中儿童对其生活环境的空间认知与其附属教育设施之间的关系. 展开更多
关键词 儿童 草图 空间认知 认知域
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AZ31镁合金板的可成形性、力学性能和组织研究
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作者 E. Yukutake J. Kaneko +4 位作者 张绍平(译) 黄金(译) 段磊(译) 田明聪(译) 胡亚民(校) 《锻造与冲压》 2007年第5期48-51,共4页
因为轧制了的镁板及其合金具有稳定的结晶组织,所以它们都有很明显的塑性各向异性,也就是具有高的兰克福值即R值(板拉力试样宽厚方向应变比)。主要原因是在室温下,镁的滑移系主要是在密排六方晶格的基面内。因此.用同样方法轧制... 因为轧制了的镁板及其合金具有稳定的结晶组织,所以它们都有很明显的塑性各向异性,也就是具有高的兰克福值即R值(板拉力试样宽厚方向应变比)。主要原因是在室温下,镁的滑移系主要是在密排六方晶格的基面内。因此.用同样方法轧制较厚的基面结构时,基面与薄板平面保持平行。所以用塑性变形减少薄板厚度非常困难.室温下可成形性很差。在拉伸、扭转、弯曲的情况下.它们显示出很差的可成形性。 展开更多
关键词 可成形性 AZ31镁合金板 结晶组织 力学性能 塑性各向异性 六方晶格 塑性变形
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