LIM domain kinases(LIMKs),which modulate cytoskeletal dynamics,are found throughout the central nervous system.The synaptic junctions between neurons show structural alteration or plasticity during neurodevelopment,le...LIM domain kinases(LIMKs),which modulate cytoskeletal dynamics,are found throughout the central nervous system.The synaptic junctions between neurons show structural alteration or plasticity during neurodevelopment,learning and memory formation,or after injury and disease;in some cases completely new connections form,while others are lost.This remodeling is under the control of the actin cytoskeleton and therefore is influenced by the activity of LIMKs(Scott and Olson,2007).Recent reports discussed in this perspective shed light on the potential role of LIMK in hippocampal dendritic spines and photoreceptor presynaptic terminals and illustrate the importance of LIMK in nerve cell function.展开更多
In December of 2019,several cases of atypical pneumonia caused by an unknown agent were reported in Wuhan,the capital city of Hubei Province in China.In early January 2020,it was announced that these cases were caused...In December of 2019,several cases of atypical pneumonia caused by an unknown agent were reported in Wuhan,the capital city of Hubei Province in China.In early January 2020,it was announced that these cases were caused by a novel coronavirus.The virus was later named Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2),which causes a disease associated with atypical pneumonia termed Corona virus disease 2019(COVID-19).Several respiratory viruses,including coronaviruses and influenza viruses tend to have prominent peaks of infection during colder seasons,especially in temperate regions.The cold temperatures,along with accompanying dry conditions can drive respiratory tract infections by assisting with viral transmission,weakening the human immune system,and increasing viral molecular stability.Though the topic of SARS-CoV-2 transmission and warm weather has been associated with misinformation campaigns,it is worth investigating since an informative answer may give an indication of the future behavior of SARS-CoV-2.展开更多
文摘LIM domain kinases(LIMKs),which modulate cytoskeletal dynamics,are found throughout the central nervous system.The synaptic junctions between neurons show structural alteration or plasticity during neurodevelopment,learning and memory formation,or after injury and disease;in some cases completely new connections form,while others are lost.This remodeling is under the control of the actin cytoskeleton and therefore is influenced by the activity of LIMKs(Scott and Olson,2007).Recent reports discussed in this perspective shed light on the potential role of LIMK in hippocampal dendritic spines and photoreceptor presynaptic terminals and illustrate the importance of LIMK in nerve cell function.
文摘In December of 2019,several cases of atypical pneumonia caused by an unknown agent were reported in Wuhan,the capital city of Hubei Province in China.In early January 2020,it was announced that these cases were caused by a novel coronavirus.The virus was later named Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2),which causes a disease associated with atypical pneumonia termed Corona virus disease 2019(COVID-19).Several respiratory viruses,including coronaviruses and influenza viruses tend to have prominent peaks of infection during colder seasons,especially in temperate regions.The cold temperatures,along with accompanying dry conditions can drive respiratory tract infections by assisting with viral transmission,weakening the human immune system,and increasing viral molecular stability.Though the topic of SARS-CoV-2 transmission and warm weather has been associated with misinformation campaigns,it is worth investigating since an informative answer may give an indication of the future behavior of SARS-CoV-2.
