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Dynamic Drought Monitoring in Guangxi Using Revised Temperature Vegetation Dryness Index 被引量:4
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作者 LU Yuan TAO Heping WU Hua 《Wuhan University Journal of Natural Sciences》 CAS 2007年第4期663-668,共6页
Moderate resolution imaging spectroradiometer (MODIS) data are very suitable for vast extent, long term and dynamic drought monitoring for its high temporal resolution, high spectral resolution and moderate spatial ... Moderate resolution imaging spectroradiometer (MODIS) data are very suitable for vast extent, long term and dynamic drought monitoring for its high temporal resolution, high spectral resolution and moderate spatial resolution. The composite Enhanced Vegetation Index (EVI) and composite land surface temperature (Ts) obtained from MODIS data MOD11A2 and MOD13A2 were used to construct the EVI-Ts space. And Temperature Vegetation Dryness Index (TVDI) was calculated to evaluate the agriculture drought in Guangxi province, China in October of 2006. The results showed that the drought area in Guangxi was evidently increasing and continuously deteriorating from the middle of September to the middle of November. The TVDI, coming from the EVI-Ts space, could effectively indicate the spatial distribution and temporal evolution of drought, so that it could provide a strong technical support for the forecasting agricultural drought in south China. 展开更多
关键词 moderate resolution imaging spectroradiometer (MODIS) enhanced vegetation index land surface temperature temperature vegetation dryness index
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A New Species of Gracixalus (Anura: Rhacophoridae) from West Guangxi, China 被引量:1
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作者 Weicai CHEN Yongjian BEI +2 位作者 Xiaowen LIAO Shichu ZHOU Yunming MO 《Asian Herpetological Research》 SCIE CSCD 2018年第2期74-84,共11页
We discovered a new species of the genus Gracixalus, Gracixalus tianlinensis sp. nov. which is morphologically almost similar to G. jinggangensis, G. jinxiuensis and G. sapaensis, but is distinguished from these speci... We discovered a new species of the genus Gracixalus, Gracixalus tianlinensis sp. nov. which is morphologically almost similar to G. jinggangensis, G. jinxiuensis and G. sapaensis, but is distinguished from these species and all other rhacophorids in China and adjoining countries by a combination of the following characters: (1) SVL 30.3-35.9 mm in male, 35.6-38.7 mm in female, (2) head length less than head width, (3) vomerine teeth absent, (4) supratympanic fold distinct, (5) axilla and posterior surface of flanks pale yellow, (6) nuptial pads distinct on Finger I and slightly visible on Finger II, (7) dorsum brown to beige, with an inverse Y-shaped dark brown marking, (8) single subgular vocal sac. Our preliminary phylogenetic analyses implied G. tianlinensis sp. nov. is sister to G. sapaensis with well-supported values. Currently, this new species is known to be distributed in montane evergreen forests in association with montane bamboo in Cenwanglaoshan National Nature Reserve, Tianlin County, Guangxi, China. 展开更多
关键词 Gracixalus tianlinensis sp. nov. Rhacophoridae southern China
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SPATIAL CORRELATION ANALYSIS BETWEEN KARST ROCKY DESERTIFICATION AND LITHOLOGY IN DU'AN YAO AUTONOMOUS COUNTY IN GUANGXI 被引量:1
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作者 HU Baoqing JIANG Shufang LIAO Chimei HUANG Qiuyan ZHOU Dequan 《Geotectonica et Metallogenia》 2004年第2期157-167,共11页
Du’an Yao Autonomous County is a typical area for the distribution of karst rocky desertification in Guangxi. The indices for the grades of rocky desertification are selected according to the scientific meaning of ka... Du’an Yao Autonomous County is a typical area for the distribution of karst rocky desertification in Guangxi. The indices for the grades of rocky desertification are selected according to the scientific meaning of karst rocky desertification and after the interpretative symbol system of rocky desertification. RS images are established by the landscape characteristics of Du’an karst and its TM image. Relying on RS & GIS means and taking land use map as base map, this paper conducts synthetic analysis on the 1999a TM image (126-043) and the correlation data involving landform, soil, geological map and GPS—database and photo on the spot, and brings forth a map showing the Du’an rocky desertification grades and a digital lithology map. As can be viewed from spatial correlation, the inherent connection is also illuminated between the various levels of rocky desertification and the carbonate lithology. 展开更多
关键词 spatial correlation analysis karst rocky desertification lithology Du'an YAO AUTONOMOUS COUNTY
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Ecological Security Assessment of Red River Basin in Guangxi
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作者 CHEN Wu-kai HUANG Wan-chang ZHOU Xing 《Meteorological and Environmental Research》 CAS 2011年第9期56-61,共6页
[Objective] The study aimed at assessing the ecological security of Red River basin in Guangxi. [Method] Firstly, the ecological security assessment index system of Red River basin was established based on the framewo... [Objective] The study aimed at assessing the ecological security of Red River basin in Guangxi. [Method] Firstly, the ecological security assessment index system of Red River basin was established based on the framework of 'pressure-state-response' model, and index information of ecological security assessment was extracted by using RS and GIS technology; afterwards, the ecological security of Red River basin was divided into five grades according to ecological security index, and the distribution and characteristics of ecological security at various levels were analyzed; finally, the measures to maintain the ecological security of Red River basin were put forward on the basis of problems in ecological security. [Result] Most areas of Red River basin in Guangxi were in generally safe state, especially Lingyun County, Fengshan County, Du'an County, Dahua County, Shanglin County, Binyang County, Guiping City, etc., and the area accounted for 74.25% of total area; next came safer state (12.74%), the regions in the two states above were the most important environmental areas of Red River basin. The ecological security problems of Red River basin were mainly related to fragile ecological environment, lagging economic development, rapid population growth, excessive development and utilization of natural resources and so forth. [Conclusion] The research could provide scientific references for the rational development and utilization of land resources, protection and construction of ecological environment in Red River basin. 展开更多
关键词 Red River basin Ecological security assessment Assessment index system Ecological security evaluation index Protection countermeasure China
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Study on Coastline Change of Guangxi in the Last 20 Years Based on RS and GIS
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作者 He Dongyan Lu Yuan Li Ning 《Meteorological and Environmental Research》 CAS 2014年第4期46-50,53,共6页
By using three different satellite remote sensing images, Guangxi coastline was extracted on the platforms of RS and GIS, and its change characteristics from 1990 to 2010 were studied. The results showed that the leng... By using three different satellite remote sensing images, Guangxi coastline was extracted on the platforms of RS and GIS, and its change characteristics from 1990 to 2010 were studied. The results showed that the length of Guangxi coastline generally decreased in the last 20 years; the total reduction length was 118.50 km, and the reduction range of coastline from 2000 to 2010 was significantly more than that from 1990 to 2000. With the development of coastal madculture and the construction of port terminals, the changes of coastline length in Fangchenggang and Qinzhou were larger. The total newly added land area was 136.81 km2, and the newly added land area in the last 10 years was greater than that in the first 10 years. The total fractal dimension of coastline presented decreasing trend; the curvature of coastline gradually decreased; the coastline will be straighter. 展开更多
关键词 COASTLINE RS GIS Fractal dimension China
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Spatial and Temporal Variation Pattern of Vegetation NPP in Guangxi Based on GIS
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作者 Chungui LIAO Xiaoju XIONG +2 位作者 Haizhen ZHU Baoqing HU Yuelian CHEN 《Asian Agricultural Research》 2018年第8期50-52,57,共4页
In order to study the rules of variations in the net primary productivity( NPP) of vegetation in Guangxi,this paper used MOD17 A3 H data to compare the spatial and temporal pattern of net primary productivity of veget... In order to study the rules of variations in the net primary productivity( NPP) of vegetation in Guangxi,this paper used MOD17 A3 H data to compare the spatial and temporal pattern of net primary productivity of vegetation in different cities by unary linear regression method and standard deviation analysis method. It obtained following results.( i) The annual average NPP of cities in Guangxi is in the range of 498. 77-803. 97 g C/m^2·a,and the Beihai has the lowest NPP and Wuzhou has the highest NPP.( ii) The region with small vegetation NPP fluctuation in Guangxi is 6 044. 22 km^2,the region with the larger fluctuation is 37 735. 38 km^2,the region with large fluctuation is43 690. 84 km^2,the region with general fluctuation is 73 938. 14 km^2,and the region with small fluctuation is 74 622. 43 km^2,most regions have small fluctuation in vegetation NPP.( iii) Regions with basically stable NPP are largest,followed by regions with slight decline.( iv)There are great differences in the spatial distribution of NPP variations in Guangxi. Regions with slight decline of NPP are mainly distributed in the northeastern Guangxi; regions with slight increase of NPP are mainly distributed in the southern Guangxi,and regions with basically stable NPP are mainly distributed in southeastern Guangxi. 展开更多
关键词 广西 植被 生产力 农业
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The Building of Network Education Platform based on Web 2.0
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作者 Liang Junyi 《International English Education Research》 2014年第7期55-57,共3页
关键词 网络教学平台 WEB 支撑系统 大厦 主动学习 网络教育 教学功能 多功能
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Study on security and protection of original ecotourism resources in the mountain areas of western Guangxi
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作者 Wu Lianglin Zhou Yongzhang +2 位作者 Chen Zhishen Ding dian Yan Xiaoping 《Ecological Economy》 2008年第1期41-48,共8页
Original ecotourism resources mainly refer to natural and human original ecotourism resources, and it's of fragility, rarity and irreversibility. As a valuable historic heritage and important tourism resources, it... Original ecotourism resources mainly refer to natural and human original ecotourism resources, and it's of fragility, rarity and irreversibility. As a valuable historic heritage and important tourism resources, it plays a significant role in developing tourism and economy in such areas as the underdeveloped areas, the mountain areas and mi-nority areas. The tourism resources in the western mountain areas of Guangxi owe superiorities and characteristics to their original ecology. Yet, western Guangxi is an ethnic region with fragile karst eco-environment, so it is special to exploit the tourism resources. The paper defines original ecotourism and analyses the specialties and advantages of the original ecotourism resources as well as the frailty of the ecotourism resources of the region. The ways of thinking are put forward for safe preservation and sustainable development of the original ecotourism resources, i.e. carrying out measures for the multi-grade protection of heritage resources, setting up a ethnic ecomuseum/ ethnic culture eco-park and a gene pool of ethnic cultures, etc. 展开更多
关键词 广西 山地 原始生态资源 自然文化遗产 种族文化
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Effects of Topographical and Edaphic Factors on the Distribution of Plant Communities in two Subtropical Karst Forests,Southwestern China 被引量:18
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作者 ZHANG Zhong-hua HU Gang NI Jian 《Journal of Mountain Science》 SCIE CSCD 2013年第1期95-104,共10页
Relationships between topography,soil properties and the distribution of plant communities on two different rocky hillsides are examined in two subtropical karst forests in the Maolan National Natural Reserve,southwes... Relationships between topography,soil properties and the distribution of plant communities on two different rocky hillsides are examined in two subtropical karst forests in the Maolan National Natural Reserve,southwestern China.Surveys of two 1-ha permanent plots at each forest,and measurements of four topographic and thirteen edaphic factors on the slopes were performed.Twoway Indicator Species Analysis(TWINSPAN) and Detrended Canonical Correspondence Analysis(DCCA) were used for the classification of plant communities and for vegetation ordination with environmental variables.One hundred 10m×10m quadrats in each plot were classified into four plant community types.A clear altitudinal gradient suggested that elevation was important in community differentiation.The topography and soil explained 51.06% and 54.69% of the variability of the distribution of plant species in the two forest plots,respectively,indicating both topographic factors(eg.elevation,slope and rock-bareness rate) and edaphic factors(e.g.total P,K and exchangeable Ca) were the important drivers of the distribution of woody plant species in subtropical karst forest.However,our results suggested that topographical factors were more important than edaphic ones in affecting local plant distribution on steep slopes with extensive rock outcrops,while edaphic factors were more influential on gentle slope and relatively thick soil over rock in subtropical karst forest.Understanding relationships between vegetation and environmental factors in karst forest ecosystems would enable us to apply these findings in vegetation management strategies and restoration of forest communities. 展开更多
关键词 植物群落类型 喀斯特森林 中国西南地区 土壤因素 地形因素 中亚热带 除趋势典范对应分析 国家级自然保护区
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A Mechanism-based 3D-QSAR and DFT Approach for the Prediction of H5N1 Entry Inhibitory Potency of 3-O-β-chacotriosyl Ursolic Acid Derivatives 被引量:3
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作者 施建成 赵丹 +1 位作者 罗敏 黄初升 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2017年第12期1987-1999,共13页
In this work, 25 3-O-β-chacotriosyl ursolic acid derivatives were employed to achieve the highly reliable and predictive 3 D-QSAR models by Co MFA and Co MSIA methods, respectively. The predictive capabilities of two... In this work, 25 3-O-β-chacotriosyl ursolic acid derivatives were employed to achieve the highly reliable and predictive 3 D-QSAR models by Co MFA and Co MSIA methods, respectively. The predictive capabilities of two constructed CoMFA and CoMSIA models were verified by the leave-one-out cross-validation method. The results showed that the cross-validated coefficient(q2) and non-cross-validated coefficient(R2) were 0.559, 0.981 in the CoMFA model and 0.696, 0.978 in the CoM SIA model, respectively, which suggests that these two models are robust and have good exterior predictive capabilities. Furthermore, based on the contour maps information of two models, ten novel inhibitors with higher inhibitory potency were designed, and the quantum chemical calculation of density functional theory(DFT) was performed to investigate the mechanism why the designed molecules have stronger inhibitory activity than the lead compound. The calculations show that the C-50 position of lead compound is a key active site for the enhancement of inhibitory activity, and it should be introduced into the large electron withdrawing group, which would result in generating potent and selective H5 N1 entry inhibitors. We expect that the results in this paper could provide important information to develop new potent H5 N1 entry inhibitors. 展开更多
关键词 H5N1 avian influenza A virus H5N1 entry inhibitor 3D-QSAR DFT molecular design
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Low carbon storage of woody debris in a karst forest in southwestern China 被引量:3
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作者 Yangyang Wu Libin Liu +3 位作者 Chunzi Guo Zhonghua Zhang Gang Hu Jian Ni 《Acta Geochimica》 EI CAS CSCD 2019年第4期576-586,共11页
The properties of woody debris(WD) vary across different forests under various soil conditions.Owing to the relatively shallow and low amounts of soils on karst terrains, it is necessary to determine the WD carbon inv... The properties of woody debris(WD) vary across different forests under various soil conditions.Owing to the relatively shallow and low amounts of soils on karst terrains, it is necessary to determine the WD carbon inventory of karst forests. In this study, we recorded WD with a basal diameter for standing snags and the largeend diameter for fallen logs of ≥ 1 cm. The carbon density of WD in a secondary karst mixed evergreen and deciduous broad-leaved forest that had been clear-cut 55 years ago in southwestern China were inventoried in a 2 ha plot. Woody debris carbon density calculated using specific gravity and carbon concentration was 4.07 Mg C ha^-1. Woody debris with diameters ≥ 10 cm(coarse WD) constituted 53.8% of total carbon storage whereas WD < 10 cm in diameters(fine WD) accounted for more pieces of WD(89.9%).Lithocarpus confinis contributed the most WD carbon(26.5%). Intermediate decayed WD was relatively more abundant, but WD with final decay contributed the least to the total pieces of WD(6.7%). The contribution of WD to carbon storage of karst forest was low compared to other forests worldwide. Significant positive correlations were found between WD carbon and biodiversity(R^2= 0.035,p < 0.01) and elevation(R^2= 0.047, p < 0.01) and negative correlations was found in outcrop coverage(R^2= 0.034, p <0.01). Further studies are needed to elucidate the ecological functions of WD to better understand their roles in maintaining biodiversity, enhancing productivity, and controlling vegetation degradation in karst forest ecosystems. 展开更多
关键词 Secondary forest Fine WOODY DEBRIS Coarse WOODY DEBRIS DEAD wood KARST SUBTROPICAL China
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Structural Insight into the Design on Oleanolic Acid Derivatives as Potent Protein Tyrosine Phosphatase 1B Inhibitors 被引量:2
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作者 施建成 涂文通 +1 位作者 罗敏 黄初升 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2017年第7期1063-1076,共14页
Oleanolic acid derivatives act as newer protein tyrosine phosphatase 1B (PTP-1B) inhibitors for type 2 diabetes mellitus (T2DM). In order to understand the structural requirement of PTP-1B inhibitors, 52 oleanolic... Oleanolic acid derivatives act as newer protein tyrosine phosphatase 1B (PTP-1B) inhibitors for type 2 diabetes mellitus (T2DM). In order to understand the structural requirement of PTP-1B inhibitors, 52 oleanolic acid derivatives were divided into a training set (34 compounds) and a test set (18 compounds). The highly reliable and predictive 3D-QSAR models were constructed by CoMFA, CoMSIA and topomer CoMFA methods, respectively. The results showed that the cross validated coefficient (q2) and non-cross-validated coefficient (R2) were 0.554 and 0.999 in the CoMFA model, 0.675 and 0.971 in the CoMSIA model, and 0.628 and 0.939 in the topomer CoMFA model, which suggests that three models are robust and have good exterior predictive capabilities. Furthermore, ten novel inhibitors with much higher inhibitory potency were designed. Our design strategy was that (i) the electronegative substituents (Cl, -CH2OH, OH and -CH2Cl) were introduced into the double bond of ring C, (ii) the hydrogen bond acceptor groups (C≡N and N atom), electronegative groups (C≡N, N atom, -COOH and -COOCH3) and bulky substituents (C6H5N) were connected to the C-3 position, which would result in generating potent and selective PTP-1B inhibitors. We expect that the results in this paper have the potential to facilitate the process of design and to develop new potent PTP-1B inhibitors. 展开更多
关键词 Type 2 diabetes mellitus (T2DM) Protein Tyrosine phosphatase 1B (PTP-1B) inhibitor 3D-QSAR Molecular design
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Fabrication and Properties of Double-Side Tl2Ba2CaCu2O8 Thin Film on CeO2 Buffered Sapphire Substrate 被引量:2
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作者 游峰 王争 +5 位作者 谢清连 季鲁 岳宏卫 赵新杰 方兰 阎少林 《Chinese Physics Letters》 SCIE CAS CSCD 2010年第4期212-214,共3页
The double-side Tl2Ba2 CaCu2O8 (Tl-2212) superconducting thin films were fabricated on CeO2 buffered sapphire substrates. The reactive magnetron sputtering technique was used to grow CeO2 buffer thin films on sapphi... The double-side Tl2Ba2 CaCu2O8 (Tl-2212) superconducting thin films were fabricated on CeO2 buffered sapphire substrates. The reactive magnetron sputtering technique was used to grow CeO2 buffer thin films on sapphire substrates. Making use of the metal cerium as a sputtering source, the depositing rate is much higher compared with the CeO2 target. The Ti-2212 thin films on CeO2 buffered sapphire substrates were fabricated by adc magnetron sputtering and post-annealing process. The x-ray diffraction indicates that the thin film is pure Tl-2212 phase with the e-axis perpendicular to the substrate surfaces, and epitaxially grown on the CeO2 buffered sapphire. The critical transition temperature Tc is around 106K, the critical current density Jc is around 3.5 MA/cm^2 at 77K, and the microwave surface resistance R8 at 77K and 10 CHz of the film is as low as 390μ Ω. 展开更多
关键词 Superconductivity Surfaces interfaces and thin films Condensed matter: structural mechanical & thermal
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Agricultural opportunity costs assessment based on planting suitability:a case study in a mountain county in southwest China 被引量:2
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作者 liu ju fu bin +2 位作者 wang yu-kuan lu ya-feng xu pei 《Journal of Mountain Science》 SCIE CSCD 2017年第12期2568-2580,共13页
Payment for ecosystem services(PES) has become an increasingly popular means of ecosystem conservation. Opportunity cost is an important factor to increase the investment efficiency of PES projects.However, the distri... Payment for ecosystem services(PES) has become an increasingly popular means of ecosystem conservation. Opportunity cost is an important factor to increase the investment efficiency of PES projects.However, the distribution of opportunity cost is usually unclear in mountainous regions due to the obvious environment changes. In this study, we developed a framework to assess the distribution of agricultural opportunity costs in mountainous regions and applied this method to Baoxing County, a typical mountainous county in Sichuan Province of southwest China. Planting suitability of 17 crops was assessed based on agricultural statistics and natural conditions data within a GIS environment.Agricultural opportunity cost was quantified with a weighted summation of farmers' willingness to cultivate and each crop's opportunity cost. Finally,specific agricultural opportunity cost was obtained according to the spatial areas of the protection programs and land use status. The results showed that agricultural opportunity costs of PES in Baoxing County were estimated to be more than $30 million,with a mean of 400.85 $/ha. Agricultural opportunity costs in mountainous regions displayed some obvious spatial variation and areas with lower agricultural opportunity costs could be selected as priority areas for PES. Our findings revealed that the planting suitability evaluation can make agricultural opportunity costs mapping more reasonable. It will be helpful for the PES programs implementation in mountainous regions. 展开更多
关键词 Opportunity cost Planting suitability Willingness to accept Ecosystem service Spatial variation Baoxing County
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Novel Retinex algorithm by interpolation and adaptive noise suppression 被引量:1
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作者 李武劲 古博 +1 位作者 黄江涛 王明辉 《Journal of Central South University》 SCIE EI CAS 2012年第9期2541-2547,共7页
In order to improve image quality,a novel Retinex algorithm for image enhancement was presented.Different from conventional algorithms,it was based on certain defined points containing the illumination information in ... In order to improve image quality,a novel Retinex algorithm for image enhancement was presented.Different from conventional algorithms,it was based on certain defined points containing the illumination information in the intensity image to estimate the illumination.After locating the points,the whole illumination image was computed by an interpolation technique.When attempting to recover the reflectance image,an adaptive method which can be considered as an optimization problem was employed to suppress noise in dark environments and keep details in other areas.For color images,it was taken in the band of each channel separately.Experimental results demonstrate that the proposed algorithm is superior to the traditional Retinex algorithms in image 展开更多
关键词 自适应方法 噪声抑制 插值技术 算法 图像质量 图像增强 强度图像 优化问题
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An MDL approach to efficiently discover communities in bipartite network 被引量:1
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作者 徐开阔 曾春秋 +2 位作者 元昌安 李川 唐常杰 《Journal of Central South University》 SCIE EI CAS 2014年第4期1353-1367,共15页
An minimum description length(MDL) criterion is proposed to choose a good partition for a bipartite network. A heuristic algorithm based on combination theory is presented to approach the optimal partition. As the heu... An minimum description length(MDL) criterion is proposed to choose a good partition for a bipartite network. A heuristic algorithm based on combination theory is presented to approach the optimal partition. As the heuristic algorithm automatically searches for the number of partitions, no user intervention is required. Finally, experiments are conducted on various datasets, and the results show that our method generates higher quality results than the state-of-art methods, cross-association and bipartite, recursively induced modules. Experiment results also show the good scalability of the proposed algorithm. The method is applied to traditional Chinese medicine(TCM) formula and Chinese herbal network whose community structure is not well known, and found that it detects significant and it is informative community division. 展开更多
关键词 网络社区 MDL 启发式算法 最小描述长度 二分网络 组合理论 自动搜索 可扩展性
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Erratum to:Effects of Topographical and Edaphic Factors on the Distribution of Plant Communities in two Subtropical Karst Forests,Southwestern China 被引量:1
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作者 ZHANG Zhong-hua HU Gang NI Jian 《Journal of Mountain Science》 SCIE CSCD 2013年第2期337-338,共2页
关键词 中国西南地区 喀斯特森林 群落分布 勘误 亚热带 TWINSPAN 地形 植物
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Isobaric vapor–liquid equilibrium for binary system of aniline+methyl-N-phenyl carbamate 被引量:1
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作者 Yuqian Li Liguo Wang +3 位作者 Peng He Kelin Huang Huiquan Li Yan Cao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2016年第10期1470-1476,共7页
In this study,the quasi-static ebulliometric method was used to measure both of the vapor pressures of methyl N-phenyl carbamate(MPC),and the isobaric vapor–liquid equilibrium(VLE) data of the aniline and MPC binary ... In this study,the quasi-static ebulliometric method was used to measure both of the vapor pressures of methyl N-phenyl carbamate(MPC),and the isobaric vapor–liquid equilibrium(VLE) data of the aniline and MPC binary system.The measured vapor pressure data of MPC,at different temperature ranging from 369.60 to 389.54 K,fitted well with the Antoine equation.The VLE data for the aniline and MPC system at(2.00,4.00,6.00,7.00 and 8.00) k Pa were correlated by both of nonrandom two-liquid(NRTL) and Wilson models.The parameters of the two models were obtained by regressing the experimental data,with the absolute temperature deviations of 0.54 K and 0.53 K,respectively.The relative volatility of the binary system calculated was all far more than 1,which gives the conclusion that the high purity MPC can be separated from aniline and MPC binary system by rectification or distillation technology. 展开更多
关键词 蒸汽液体平衡 苯胺 甲基 N 苯基氨基甲酸酯 NRTL 威尔森
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Molecular Docking and Design of Novel Heterodimers of Donepezil and Huperzine Fragments as Acetylcholinesterase Inhibitors 被引量:4
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作者 黄初升 涂文通 +1 位作者 罗敏 施建成 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2016年第6期839-848,共10页
To provide hints for the design of new acetylcholinesterase(ACh E) inhibitors with higher potency and specificity, the binding modes of novel heterodimers comprised of donepezil and huperzine A fragments with ACh E ... To provide hints for the design of new acetylcholinesterase(ACh E) inhibitors with higher potency and specificity, the binding modes of novel heterodimers comprised of donepezil and huperzine A fragments with ACh E were explored by employing the docking simulations. The results show that the binding mode of S-17b(the most potent inhibitor in Ref. 2, i.e., Bioorg. Med. Chem. 2013, 21, 676-683) is clearly different from that of donepezil, while the binding modes of other heterodimers in Ref. 2 are the same as that of donepezil. In addition, based on the binding mode and structure modification of S-17 b, two novel inhibitors(S-17b1 and S-17bb1) with much higher inhibitory potency than S-17 b were obtained. Our design strategy was to replace the hupyridone moiety of S-17 b with the bulky group, and to replace the dimethoxyindanone moiety of S-17 b with more hydrophobic and bulky group with a highly positive charge, which would result in generating potent and selective AChE inhibitors. 展开更多
关键词 molecular docking acetylcholinesterase Alzheimer's disease
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New ternary compound La_8Al_(13)Sn_3 被引量:1
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作者 HE Wei XIA Xiuwen +2 位作者 ZHANG Jiliang HUANG Jinli LIU Yixin 《Rare Metals》 SCIE EI CAS CSCD 2009年第5期491-493,共3页
A new ternary compound La8Al13Sn3 was synthesized and studied by means of X-ray powder diffraction technique. The compound La8Al13Sn3 crystallizes in a hexagonal AlB2-type structure with space group P6/mmm (No. 191)... A new ternary compound La8Al13Sn3 was synthesized and studied by means of X-ray powder diffraction technique. The compound La8Al13Sn3 crystallizes in a hexagonal AlB2-type structure with space group P6/mmm (No. 191) and the lattice parameters a = 0.44919(1) nm and c = 0.43835(1) nm. The Smith and Snyder figure of merit for index, FN, is F30 = 197.3(30). The Rietveld refinement for the crystal structure of the compound was carried out successfully. The liability R-factors of Rietveld refinement are Rp = 0.114 and Rwp = 0.148. The compound La8Al13Sn3 decomposes into LaAl2 with cubic structure and space group Fd 3m (227), LaAl3 with hexagonal structure and space group P63/mmc (194), and Sn at 720°C. 展开更多
关键词 CRYSTALLOGRAPHY X-ray diffraction Reitveld method rare earth compounds
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