[ Objective] To investigate safety and clinical efficacy of compound Chinese herbal medicine （Gongshukang） against cow endometritis. [ Method] Clinical trials were constructed in cow community of Qingzhen and Wudang...[ Objective] To investigate safety and clinical efficacy of compound Chinese herbal medicine （Gongshukang） against cow endometritis. [ Method] Clinical trials were constructed in cow community of Qingzhen and Wudang. A total of 311 parental cows suffering from endometdtis were selected and randomly divided into two groups. The cows in the group I were gavaged with Gongshukang, and those in the group II were adminis- trated with long-acting oxytetracycline hydrochloride. Therapy was based on the severity of illness. [ Result] The cure rate and effective rate were high in mild and moderate cases of the two groups, but the cows in the group I needed shorter time to be in heat than those in the group II. The pregnancy rate was significantly higher in the group I than in the group II （P 〈 0.05）. For severe cases, the cure rate of the group I was significantly lower than that in the group II （ P 〈 0.01 ）, but the effective rate of the group I was significantly higher than that in the group II （ P 〈 0.05）. [ Conclusion] The Gongshukang has antibacterial activity and anti-inflammatory activity, induces sexual desire and increases pregnancy rate. It has better efficacy against mild and moderate endometritis than long-acting oxytetracycline hydrochloride, but its efficacy is worse in severe cases.展开更多
基金funded by the Key Agricultural Research Project of Guizhou Province [Guizhou Science and Technology Department co-NY (2007) 3008]Project of Guizhou Science and Technology Department (Innovation Project for Institutes of Guizhou Science and Technology Department [2010]4004)
文摘[ Objective] To investigate safety and clinical efficacy of compound Chinese herbal medicine （Gongshukang） against cow endometritis. [ Method] Clinical trials were constructed in cow community of Qingzhen and Wudang. A total of 311 parental cows suffering from endometdtis were selected and randomly divided into two groups. The cows in the group I were gavaged with Gongshukang, and those in the group II were adminis- trated with long-acting oxytetracycline hydrochloride. Therapy was based on the severity of illness. [ Result] The cure rate and effective rate were high in mild and moderate cases of the two groups, but the cows in the group I needed shorter time to be in heat than those in the group II. The pregnancy rate was significantly higher in the group I than in the group II （P 〈 0.05）. For severe cases, the cure rate of the group I was significantly lower than that in the group II （ P 〈 0.01 ）, but the effective rate of the group I was significantly higher than that in the group II （ P 〈 0.05）. [ Conclusion] The Gongshukang has antibacterial activity and anti-inflammatory activity, induces sexual desire and increases pregnancy rate. It has better efficacy against mild and moderate endometritis than long-acting oxytetracycline hydrochloride, but its efficacy is worse in severe cases.
