Objective Lyme disease and Human granulocytic anaplasmosis are tick-borne diseases caused by Borrelia burgdorferi and Anoplasrna phagocytophilum respectively. We have investigated infection and co-infection of the two...Objective Lyme disease and Human granulocytic anaplasmosis are tick-borne diseases caused by Borrelia burgdorferi and Anoplasrna phagocytophilum respectively. We have investigated infection and co-infection of the two diseases in the population of forest areas of eight provinces in China by measuring seroprevalence of antibodies against B. burgdorferi and A. phagocytophilum. Methods Forest areas in 8 provinces were chosen for investigation using whole sampling and questionnaire survey methods. 3 669 serum samples from people in the forest areas were tested for the presence of antibodies by indirect immunofluorescent assay （IFA）. Results Seroprevalence against B. burgdorferi was 3% to 15% and against A. phagocytophilum was 2% to 18% in the study sites in the 8 provinces in China. We also found co-infection of B. burgdorferi and A. phagocytophilum in 7 of the 8 provinces （the exception being the Miyun area in Beijing）. The seroprevalence for both B. burgdorferi and A. phagocytophilum was significantly higher among people exposed to ticks than among people who were not exposed to ticks. Conclusion We conclude that both pathogens are endemic in the forest areas in the eight provinces, but the prevalence of B. burgdorferi and A. phagocytophilum differs between the provinces.展开更多
To the Editor： Anthrax is a zoonosis to which most mammals, especially herbivores, are considered susceptible. Humans almost invariably contract anthrax from handling infected animals, from carcasses of animals that...To the Editor： Anthrax is a zoonosis to which most mammals, especially herbivores, are considered susceptible. Humans almost invariably contract anthrax from handling infected animals, from carcasses of animals that have died from the disease, or from the meat, skin, hair, bones, etc., of such animals, Guizhou Province is a historical epicenter of anthrax in the southwest of China？ In June 2013, an epidemic suspected to be anthrax consisting of five human cases occurred in Wengan County. The clinical symptoms included erythema, papules, and vesicles on the skin of the hands and forearm, accompanied by tissue swelling, infiltration.展开更多
基金supported by the 12th Five-Year Major National Science and Technology Projects of China (No. 2012ZX10004219-007) and ( No. 2013ZX10004001)
文摘Objective Lyme disease and Human granulocytic anaplasmosis are tick-borne diseases caused by Borrelia burgdorferi and Anoplasrna phagocytophilum respectively. We have investigated infection and co-infection of the two diseases in the population of forest areas of eight provinces in China by measuring seroprevalence of antibodies against B. burgdorferi and A. phagocytophilum. Methods Forest areas in 8 provinces were chosen for investigation using whole sampling and questionnaire survey methods. 3 669 serum samples from people in the forest areas were tested for the presence of antibodies by indirect immunofluorescent assay （IFA）. Results Seroprevalence against B. burgdorferi was 3% to 15% and against A. phagocytophilum was 2% to 18% in the study sites in the 8 provinces in China. We also found co-infection of B. burgdorferi and A. phagocytophilum in 7 of the 8 provinces （the exception being the Miyun area in Beijing）. The seroprevalence for both B. burgdorferi and A. phagocytophilum was significantly higher among people exposed to ticks than among people who were not exposed to ticks. Conclusion We conclude that both pathogens are endemic in the forest areas in the eight provinces, but the prevalence of B. burgdorferi and A. phagocytophilum differs between the provinces.
文摘To the Editor： Anthrax is a zoonosis to which most mammals, especially herbivores, are considered susceptible. Humans almost invariably contract anthrax from handling infected animals, from carcasses of animals that have died from the disease, or from the meat, skin, hair, bones, etc., of such animals, Guizhou Province is a historical epicenter of anthrax in the southwest of China？ In June 2013, an epidemic suspected to be anthrax consisting of five human cases occurred in Wengan County. The clinical symptoms included erythema, papules, and vesicles on the skin of the hands and forearm, accompanied by tissue swelling, infiltration.
