Jetting-based bioprinting facilitates contactless drop-on-demand deposition of subnanoliter droplets at well-defined positions to control the spatial arrangement of cells,growth factors,drugs,and biomaterials in a hig...Jetting-based bioprinting facilitates contactless drop-on-demand deposition of subnanoliter droplets at well-defined positions to control the spatial arrangement of cells,growth factors,drugs,and biomaterials in a highly automated layer-by-layer fabrication approach.Due to its immense versatility,jetting-based bioprinting has been used for various applications,including tissue engineering and regenerative medicine,wound healing,and drug development.A lack of in-depth understanding exists in the processes that occur during jetting-based bioprinting.This review paper will comprehensively discuss the physical considerations for bioinks and printing conditions used in jetting-based bioprinting.We first present an overview of different jetting-based bioprinting techniques such as inkjet bioprinting,laser-induced forward transfer bioprinting,electrohydrodynamic jet bioprinting,acoustic bioprinting and microvalve bioprinting.Next,we provide an in-depth discussion of various considerations for bioink formulation relating to cell deposition,print chamber design,droplet formation and droplet impact.Finally,we highlight recent accomplishments in jetting-based bioprinting.We present the advantages and challenges of each method,discuss considerations relating to cell viability and protein stability,and conclude by providing insights into future directions of jetting-based bioprinting.展开更多
The article Jetting-based bioprinting:process,dispense physics,and applications,written by Wei Long Ng and Viktor Shkolnikov,was originally published electronically on the publisher’s internet portal on 12 July 2024 ...The article Jetting-based bioprinting:process,dispense physics,and applications,written by Wei Long Ng and Viktor Shkolnikov,was originally published electronically on the publisher’s internet portal on 12 July 2024 without open access.展开更多
A prototype cleanroom for hazardous testing and handling of satellites prior to launcher encapsulation,satisfying the ISO8 standard has been designed and analyzed in terms of performances.Unsteady Reynolds Averaged Na...A prototype cleanroom for hazardous testing and handling of satellites prior to launcher encapsulation,satisfying the ISO8 standard has been designed and analyzed in terms of performances.Unsteady Reynolds Averaged Navier-Stokes(URANS)models have been used to study the related flow field and particulate matter(PM)dispersion.The outcomes of the URANS models have been validated through comparison with equivalent large-eddy simulations.Special attention has been paid to the location and shape of the air intakes and their orientation in space,in order to balance the PM convection and diffusion inside the cleanroom.Forming a cyclone-type flow pattern inside the cleanroom is a key to maintaining a high ventilation efficiency.展开更多
Background Deep 3D morphable models(deep 3DMMs)play an essential role in computer vision.They are used in facial synthesis,compression,reconstruction and animation,avatar creation,virtual try-on,facial recognition sys...Background Deep 3D morphable models(deep 3DMMs)play an essential role in computer vision.They are used in facial synthesis,compression,reconstruction and animation,avatar creation,virtual try-on,facial recognition systems and medical imaging.These applications require high spatial and perceptual quality of synthesised meshes.Despite their significance,these models have not been compared with different mesh representations and evaluated jointly with point-wise distance and perceptual metrics.Methods We compare the influence of different mesh representation features to various deep 3DMMs on spatial and perceptual fidelity of the reconstructed meshes.This paper proves the hypothesis that building deep 3DMMs from meshes represented with global representations leads to lower spatial reconstruction error measured with L_(1) and L_(2) norm metrics and underperforms on perceptual metrics.In contrast,using differential mesh representations which describe differential surface properties yields lower perceptual FMPD and DAME and higher spatial fidelity error.The influence of mesh feature normalisation and standardisation is also compared and analysed from perceptual and spatial fidelity perspectives.Results The results presented in this paper provide guidance in selecting mesh representations to build deep 3DMMs accordingly to spatial and perceptual quality objectives and propose combinations of mesh representations and deep 3DMMs which improve either perceptual or spatial fidelity of existing methods.展开更多
HP最近推出了3款动能服务器，分别是4路高密度服务器动能rx4640、8路动能rx7620和16路动能rx8620，这些服务器与原有的低端动能rx2600系列、rx5670系列和高端的动能超腾系列起，形成了从2路到64路在内的全面完整的安腾2服务器产品线。...HP最近推出了3款动能服务器，分别是4路高密度服务器动能rx4640、8路动能rx7620和16路动能rx8620，这些服务器与原有的低端动能rx2600系列、rx5670系列和高端的动能超腾系列起，形成了从2路到64路在内的全面完整的安腾2服务器产品线。这些服务器都可以支持HP-UX 11i、Windows Server 2003、OpenVMS和Linux等操作系统．展开更多
基金support from NTU Presidential Postdoctoral Fellowship.
文摘Jetting-based bioprinting facilitates contactless drop-on-demand deposition of subnanoliter droplets at well-defined positions to control the spatial arrangement of cells,growth factors,drugs,and biomaterials in a highly automated layer-by-layer fabrication approach.Due to its immense versatility,jetting-based bioprinting has been used for various applications,including tissue engineering and regenerative medicine,wound healing,and drug development.A lack of in-depth understanding exists in the processes that occur during jetting-based bioprinting.This review paper will comprehensively discuss the physical considerations for bioinks and printing conditions used in jetting-based bioprinting.We first present an overview of different jetting-based bioprinting techniques such as inkjet bioprinting,laser-induced forward transfer bioprinting,electrohydrodynamic jet bioprinting,acoustic bioprinting and microvalve bioprinting.Next,we provide an in-depth discussion of various considerations for bioink formulation relating to cell deposition,print chamber design,droplet formation and droplet impact.Finally,we highlight recent accomplishments in jetting-based bioprinting.We present the advantages and challenges of each method,discuss considerations relating to cell viability and protein stability,and conclude by providing insights into future directions of jetting-based bioprinting.
文摘The article Jetting-based bioprinting:process,dispense physics,and applications,written by Wei Long Ng and Viktor Shkolnikov,was originally published electronically on the publisher’s internet portal on 12 July 2024 without open access.
基金funded by Space Research and Innovation Network (www.sprint.ac.uk)for Technology Grants (OW131743P4V4M,OW131797P4V2B,ZX and CY)grateful to NERC (www.nerc.ac.uk)for the Grant (NE/W002841/1,ZX)to complete the writing of the paper。
文摘A prototype cleanroom for hazardous testing and handling of satellites prior to launcher encapsulation,satisfying the ISO8 standard has been designed and analyzed in terms of performances.Unsteady Reynolds Averaged Navier-Stokes(URANS)models have been used to study the related flow field and particulate matter(PM)dispersion.The outcomes of the URANS models have been validated through comparison with equivalent large-eddy simulations.Special attention has been paid to the location and shape of the air intakes and their orientation in space,in order to balance the PM convection and diffusion inside the cleanroom.Forming a cyclone-type flow pattern inside the cleanroom is a key to maintaining a high ventilation efficiency.
基金Supported by the Centre for Digital Entertainment at Bournemouth University by the UK Engineering and Physical Sciences Research Council(EPSRC)EP/L016540/1 and Humain Ltd.
文摘Background Deep 3D morphable models(deep 3DMMs)play an essential role in computer vision.They are used in facial synthesis,compression,reconstruction and animation,avatar creation,virtual try-on,facial recognition systems and medical imaging.These applications require high spatial and perceptual quality of synthesised meshes.Despite their significance,these models have not been compared with different mesh representations and evaluated jointly with point-wise distance and perceptual metrics.Methods We compare the influence of different mesh representation features to various deep 3DMMs on spatial and perceptual fidelity of the reconstructed meshes.This paper proves the hypothesis that building deep 3DMMs from meshes represented with global representations leads to lower spatial reconstruction error measured with L_(1) and L_(2) norm metrics and underperforms on perceptual metrics.In contrast,using differential mesh representations which describe differential surface properties yields lower perceptual FMPD and DAME and higher spatial fidelity error.The influence of mesh feature normalisation and standardisation is also compared and analysed from perceptual and spatial fidelity perspectives.Results The results presented in this paper provide guidance in selecting mesh representations to build deep 3DMMs accordingly to spatial and perceptual quality objectives and propose combinations of mesh representations and deep 3DMMs which improve either perceptual or spatial fidelity of existing methods.
文摘HP最近推出了3款动能服务器，分别是4路高密度服务器动能rx4640、8路动能rx7620和16路动能rx8620，这些服务器与原有的低端动能rx2600系列、rx5670系列和高端的动能超腾系列起，形成了从2路到64路在内的全面完整的安腾2服务器产品线。这些服务器都可以支持HP-UX 11i、Windows Server 2003、OpenVMS和Linux等操作系统．
