Cardiovascular diseases(CVDs)are one of the most urgent threats to humans worldwide,which are responsible for almost one-third of global mortality.Over the last decade,research on flexible electronics for monitoring a...Cardiovascular diseases(CVDs)are one of the most urgent threats to humans worldwide,which are responsible for almost one-third of global mortality.Over the last decade,research on flexible electronics for monitoring and treatment of CVDs has attracted tremendous attention.In contrast to conventional medical instruments in hospitals that are usually bulky,hard to move,monofunctional,and time-consuming,flexible electronics are capable of continuous,noninvasive,real-time,and portable monitoring.Notable progress has been made in this emerging field,and thus a number of significant achievements and concomitant research prospects deserve attention for practical implementation.Here,we comprehensively review the latest progress of flexible electronics for CVDs,focusing on new functions provided by flexible electronics.First,the characteristics of CVDs and flexible electronics and the foundation of their combination are briefly reviewed.Then,four representative applications of flexible electronics for CVDs are elaborated:blood pressure(BP)monitoring,electrocardiogram(ECG)monitoring,echocardiogram monitoring,and direct epicardium monitoring.Their operational principles,progress,merits and demerits,and future efforts are discussed.Finally,the remaining challenges and opportunities for flexible electronics for cardiovascular healthcare are outlined.展开更多
基金National Natural Science Foundation of China(grant 52105575)National High Level Hospital Clinical Research Funding(grants 2022-GSP-GG-19 and 2023-GSP-QN-23)+3 种基金Fundamental Research Funds for the Central Universities(grant QTZX23063)Proof of Concept Foundation of Xidian University Hangzhou Institute of Technology(grant GNYZ2023YL0302)Hainan Province Science and Technology Special Fund(grant ZDYF2022SHFZ116)Hainan Provincial Natural Science Foundation of China(grant 823RC564).
文摘Cardiovascular diseases(CVDs)are one of the most urgent threats to humans worldwide,which are responsible for almost one-third of global mortality.Over the last decade,research on flexible electronics for monitoring and treatment of CVDs has attracted tremendous attention.In contrast to conventional medical instruments in hospitals that are usually bulky,hard to move,monofunctional,and time-consuming,flexible electronics are capable of continuous,noninvasive,real-time,and portable monitoring.Notable progress has been made in this emerging field,and thus a number of significant achievements and concomitant research prospects deserve attention for practical implementation.Here,we comprehensively review the latest progress of flexible electronics for CVDs,focusing on new functions provided by flexible electronics.First,the characteristics of CVDs and flexible electronics and the foundation of their combination are briefly reviewed.Then,four representative applications of flexible electronics for CVDs are elaborated:blood pressure(BP)monitoring,electrocardiogram(ECG)monitoring,echocardiogram monitoring,and direct epicardium monitoring.Their operational principles,progress,merits and demerits,and future efforts are discussed.Finally,the remaining challenges and opportunities for flexible electronics for cardiovascular healthcare are outlined.