A 36- year-old man presented with a giant congenital melanocytic n evus and multiple disseminated melanocytic nevi. After he had developed neurological sym ptoms (grand mal seizures), a cerebral metastasis of a malign...A 36- year-old man presented with a giant congenital melanocytic n evus and multiple disseminated melanocytic nevi. After he had developed neurological sym ptoms (grand mal seizures), a cerebral metastasis of a malignant melanoma withou t a primary melanoma was found. The patient was diagnosed as having a neurocutan eous melanosis with a cerebral metastasis. In spite of a variety of therapeutic attempts (surgery, radiation therapy and chemotherapy) he followed a rapidly pro gressive, lethal course with increased intracranial pressure, hydrocephalus and spinal metastases.展开更多
文摘A 36- year-old man presented with a giant congenital melanocytic n evus and multiple disseminated melanocytic nevi. After he had developed neurological sym ptoms (grand mal seizures), a cerebral metastasis of a malignant melanoma withou t a primary melanoma was found. The patient was diagnosed as having a neurocutan eous melanosis with a cerebral metastasis. In spite of a variety of therapeutic attempts (surgery, radiation therapy and chemotherapy) he followed a rapidly pro gressive, lethal course with increased intracranial pressure, hydrocephalus and spinal metastases.