PURPOSE: To examine the long-term longitudinal changes in corneal surface configuration as determined by Fourier series harmonic analysis of videokeratography data and of visual acuity and refraction after penetrating...PURPOSE: To examine the long-term longitudinal changes in corneal surface configuration as determined by Fourier series harmonic analysis of videokeratography data and of visual acuity and refraction after penetrating keratoplasty (PK). DESIGN: Interventional case series. METHODS: One hundred thirty eyes of 130 consecutive patients who were scheduled for PK using 16 interrupted 10-0 nylon sutures were recruited. Spherical equivalent power, regular astigmatism component, irregular astigmatism (asymmetry and higher-order irregularity) component of the central cornea as determined by Fourier analysis of videokeragraphic data, spectacle-corrected visual acuity, and spherical equivalent were examined at 1 week, and at 1, 3, 6, 9, 12, 18, and 24 months after PK. RESULTS: Spherical equivalent power increased considerably for up to 1 month after PK, but thereafter showed no further appreciable change up to the final follow-up at 24 months. The regular astig matism component decreased markedly for up to 6 months after PK, while the total irregular astigmatism (sum of the asymmetry and higher-order irregularity) component decreased considerably up to approximately 3 months, and then these showed no further relevant change for up to 24 months. Spectacle-corrected visual acuity also improvedmarkedly until approximately 3 months after PK, after which it was virtually stable. Furthermore, important correlations were found between regular and irregular astigmatism and the spectacle corrected visual acuity. CONCLUSIONS: Corneal surface configuration after PK appears to be stable by approximately 6months after PK, concurrent with postkeratoplasty stabilization of visual acuity.展开更多
BACKGROUND AND OBJECTIVE: To compare the influence of low- molecular- weight viscoelastics on postoperative intraocular pressure (IOP) and corneal endothelial cell loss after phacoemulsification surgery. PATIENTS AND ...BACKGROUND AND OBJECTIVE: To compare the influence of low- molecular- weight viscoelastics on postoperative intraocular pressure (IOP) and corneal endothelial cell loss after phacoemulsification surgery. PATIENTS AND METHODS: Sixty- nine eyes undergoing phacoemulsification surgery were randomized to have either Opegan (Santen Pharmaceuticals, Osaka, Japan) alone or the soft- shell technique using Viscoat (Alcon Surgical, Fort Worth, TX) during phacoemulsification. The IOP was measured preoperatively and at 5 and 24 hours postoperatively. Intraoperative factors and corneal endothelial cell loss were also examined. RESULTS: Mean IOP was increased at 5 hours after surgery but returned to preoperative levels at 24 hours in the Opegan group, whereas it remained higher at 24 hours than at preoperative levels in the soft- shell group. When comparing groups, IOP at 5 and 24 hours postoperatively in the Opegan group was significantly less than that in the soft- shell group. Corneal endothelial cell loss was approximately the same in the two groups. CONCLUSION: The increase in IOP following phacoemulsification surgery with the use of Opegan was less than that with the soft- shell technique using Viscoat, although endothelial injury was almost the same.展开更多
文摘PURPOSE: To examine the long-term longitudinal changes in corneal surface configuration as determined by Fourier series harmonic analysis of videokeratography data and of visual acuity and refraction after penetrating keratoplasty (PK). DESIGN: Interventional case series. METHODS: One hundred thirty eyes of 130 consecutive patients who were scheduled for PK using 16 interrupted 10-0 nylon sutures were recruited. Spherical equivalent power, regular astigmatism component, irregular astigmatism (asymmetry and higher-order irregularity) component of the central cornea as determined by Fourier analysis of videokeragraphic data, spectacle-corrected visual acuity, and spherical equivalent were examined at 1 week, and at 1, 3, 6, 9, 12, 18, and 24 months after PK. RESULTS: Spherical equivalent power increased considerably for up to 1 month after PK, but thereafter showed no further appreciable change up to the final follow-up at 24 months. The regular astig matism component decreased markedly for up to 6 months after PK, while the total irregular astigmatism (sum of the asymmetry and higher-order irregularity) component decreased considerably up to approximately 3 months, and then these showed no further relevant change for up to 24 months. Spectacle-corrected visual acuity also improvedmarkedly until approximately 3 months after PK, after which it was virtually stable. Furthermore, important correlations were found between regular and irregular astigmatism and the spectacle corrected visual acuity. CONCLUSIONS: Corneal surface configuration after PK appears to be stable by approximately 6months after PK, concurrent with postkeratoplasty stabilization of visual acuity.
文摘BACKGROUND AND OBJECTIVE: To compare the influence of low- molecular- weight viscoelastics on postoperative intraocular pressure (IOP) and corneal endothelial cell loss after phacoemulsification surgery. PATIENTS AND METHODS: Sixty- nine eyes undergoing phacoemulsification surgery were randomized to have either Opegan (Santen Pharmaceuticals, Osaka, Japan) alone or the soft- shell technique using Viscoat (Alcon Surgical, Fort Worth, TX) during phacoemulsification. The IOP was measured preoperatively and at 5 and 24 hours postoperatively. Intraoperative factors and corneal endothelial cell loss were also examined. RESULTS: Mean IOP was increased at 5 hours after surgery but returned to preoperative levels at 24 hours in the Opegan group, whereas it remained higher at 24 hours than at preoperative levels in the soft- shell group. When comparing groups, IOP at 5 and 24 hours postoperatively in the Opegan group was significantly less than that in the soft- shell group. Corneal endothelial cell loss was approximately the same in the two groups. CONCLUSION: The increase in IOP following phacoemulsification surgery with the use of Opegan was less than that with the soft- shell technique using Viscoat, although endothelial injury was almost the same.
