Neurological involvement in Behcet＇s disease （BD）, namely, neuro-Behcet＇s disease （NBD）, causes devastating central ner- vous system （CNS） complications and is present in 5% to 30% of patients with BD.1 Immuno...Neurological involvement in Behcet＇s disease （BD）, namely, neuro-Behcet＇s disease （NBD）, causes devastating central ner- vous system （CNS） complications and is present in 5% to 30% of patients with BD.1 Immunological and molecular pathways are involved in NBD and include the release ofinterleukin （IL）- 1, -6 and -8, and TNF-α and IFN-γ into cerebrospinal fluid （CSF）,2 which reflects a nonspecific inflammatory pattern that is comnatihle with anta-inflammatnry disease pathways.展开更多
文摘Neurological involvement in Behcet＇s disease （BD）, namely, neuro-Behcet＇s disease （NBD）, causes devastating central ner- vous system （CNS） complications and is present in 5% to 30% of patients with BD.1 Immunological and molecular pathways are involved in NBD and include the release ofinterleukin （IL）- 1, -6 and -8, and TNF-α and IFN-γ into cerebrospinal fluid （CSF）,2 which reflects a nonspecific inflammatory pattern that is comnatihle with anta-inflammatnry disease pathways.
