51 CASES OF GASTRIC CANCER TREATED BY THE TURBIDITY DESCENDING AND STASIS RESOLVING METHOD

Gastric cancer is one of the commonestmalignant tumors. Since the 1980s, researchon its treatment by traditional Chinese med-icine has made considerable progress. Theauthors treated 51 cases of the disease from1983 to 1989 in the OPD by the method ofdescending op and resolving stasis andobtained fairly satisfactory results as re-ported below.

Effects of Wenglian Jiedu decoction on expression of serum IL-18, TNF-α and MUC2 in colon tissue of ulcerative colitis rats

Objective:To study the effect of Wenglian jiedu decoction on the expression of serum interleukin-18(IL-18),tumor necrosis factor-α(TNF--α)and colonic mucin-2(MUC2)in rats with ulcerative colitis of turbid toxin type,and to explore its mechanism.Methods:60 Wistar male rats were randomly divided into model group,Wenglian jiedu decoction low,middle and high dose groups,mesalazine group and blank group.Except for the blank group,the rat model of ulcerative colitis was established by trinitrobenzenesulfonic acid(TNBS)/ethanol compound method.The general condition,body weight,fecal properties and occult blood of rats were observed 2 weeks after administration.The disease activity index(Diseaseactivityindex,DAI)was scored,the content of MUC2 protein was detected by immunohistochemical method,and the contents of IL-18 and TNF-αin serum were detected by enzyme-linked immunosorbent assay(Elisa).Results:compared with the blank group,the DAI score increased,the contents of IL-18 and TNF-αincreased significantly,and the content of MUC2 protein decreased in the model group.Compared with the model group,the DAI score,the content of IL-18 and TNF-αdecreased and the content of MUC2 protein increased in each treatment group.Compared with the mesalazine group,the DAI score and the contents of IL-18 and TNF-αin the high and middle dose groups had no significant difference.Compared with the low dose group,the DAI score in the mesalazine group and the high and middle dose group decreased,and the contents of IL-18 and TNF-αdecreased.Conclusion:Wenglian jiedu decoction can regulate the immune system of intestinal epithelium by regulating the levels of serum IL-18 and TNF-αand increasing the expression of MUC2 protein,so as to achieve the purpose of repairing intestinal mucosa.

Research progress on markers of urine tubular damage in idiopathic membranous nephropathy

Idiopathic membranous nephropathy is a common primary glomerular disease.Recently,it has been found that the progression and prognosis of glomerular diseases are not only related to the glomeruli itself,but also to the severity of renal tubular injury.Although blood creatinine and urinary protein are recognized biomarkers,they appear late,are insensitive,lack specificity,and are difficult to respond to IMN conditions in a timely and accurate manner.Markers such as N-acetyl-β-D-glucosaminidase,kidney injury molecule 1,neutrophil gelatinase-associated lipoprotein in urine can dynamically reflect the progress of kidney injury in the early stage,and are detected as noninvasive,so It has been applied in IMN,but such research is lacking,and the scope needs to be further expanded and discussed in depth.

Professor Jia Chunsheng's instruction on clinical application of"elements for acupuncture effect orientation"in the Song to Elucidate Mysteries

Professor Jia Chunsheng is one of the sixth of old traditional Chinese medicine experts,and often instructs students in ordinary clinics to attach importance to learning and clinical practices of classic works.Now Professor Jia Chunsheng selects a poet-Song to Elucidate Mysteries in the Guidelines of Acupuncture Classic by Dou Hanqing in the Jin and Yuan Dynasties,and requires the students to read carefully,investigate deeply,and apply at times;Moreover,Professor Jia Chunsheng discusses the"important factors to achieve good clinical therapeutic effects by acupuncture"contained in the Song to Elucidate Mysteries,in many aspects of understanding acupoint characteristics,defining clearly acupoint compatibility,selecting appropriate needling manipulation,how to determine needling depth,how to determine needling direction,how to determine needle retention time,and how to select acupuncture&moxibustion method,etc.Now they are discussed as follows,to discover and spread Dou's acupuncture technique and to increase clinical therapeutic effects.

Theoretical Discussion on Treatment of Cubital Tunnel Syndrome Based on Theory of Liver,Spleen and Kidney

Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second highest among peripheral nerve entrapment diseases,and it is one of the common clinical diseases.The theory of liver,spleen and kidney can guide the treatment of cubital tunnel syndrome with traditional Chinese medicine and acupuncture.By discussing the traditional Chinese medicine(TCM)pathogenesis and treatment principles of cubital tunnel syndrome,it provides modern medical theoretical support for TCM treatment of cubital tunnel syndrome.

Medicine in Future and Advantages of Integrated Chinese and Western Medicine

The history of medical development shows that oriental medicine, or traditional medicine, was born through medical practice during the times when science and technology were immature and underdeveloped, whereas with the development of science and technology, Western medicine, or modern medicine, was born through experimental analysis and research. With the development of medicine, the pros and cons of both medical systems become increasingly evident. How to integrate them and learn from each other will be the direction of future development of medicine. The formation and development of integrated medicine will, inevitably, usher in a new era for medicine.

关于中药药理研究中“证”的动物模型的复制

本文就近二十年来国内以中医理论体系中'证'为基础而建立动物模型的进展加以综述。提出了建立'证'的动物模型的指导原则和检验方法,并详细介绍了阴虚、阳虚、气虚、血虚、脾虚和血瘀等各种'证'动物模型的复制及生理生化指标的变化。文中还讨论了'证'动物模型在探讨中药作用机制中的地位和重要意义。