趋化因子RANTES及MIP-1α在肾移植术后急性排斥反应中的作用

目的探讨趋化因子RANTES及MIP-１α表达在肾移植术后急性排斥反应中的作用。方法采用RT-PCR法分析５７例肾移植术后发生急性排斥反应患者及１９例未发生反应患者移植肾活检组织中RANTES和MIP-１α的基因表达。结果１９例无急性排斥反应肾活检组织中仅４例（２１％）轻度表达RANTES，５例（２６％）轻度表达MIP-１α。５７例急性排斥反应肾活检组织中３８例（６６．７％）强烈表达RANTES，１４例轻度表达，５例无表达；４１例（７２％）强烈表达MIP-１α，１４例轻度表达，２例无表达，两组间比较差异极显著（P＜０．００１）。结论趋化因子RANTES及MIP-１α表达在肾移植术后急性排斥反应中可能具有重要作用。

Egg rejection and egg recognition mechanisms in Oriental Reed Warblers

Background:Nest parasitism by cuckoos(Cuculus spp.)results in enormous reproductive failure and forces hosts to evolve antiparasitic strategies,i.e.,recognition of own eggs and rejection of cuckoo eggs.There are often sexual conflicts between male and female individuals in the expression of antiparasitic behavior due to the differences in reproductive inputs and division of labor.Methods:By adding a foreign egg made of blue soft clay to the host nest during early incubation period in the field,and by removing several host eggs and adding experimental eggs to control the proportion of two egg types in the nest,we examined egg rejection ability,egg recognition mechanism and sexual difference in egg rejection of the Oriental Reed Warbler(Acrocephalus orientalis),one of the major hosts of Common Cuckoos(Cuculus canorus).Results:Our results indicated that Oriental Reed Warblers can recognize and reject nearly 100%(73/75)of the nonmimetic eggs made of blue soft clay,and they could reject foreign eggs with 100%accuracy,regardless of the ratio of experimental eggs and its own eggs in the nest.Furthermore,all cases of egg rejections recorded by videos were only carried out by females.Conclusions:Oriental Reed Warblers have a high egg recognition ability and show a true recognition mechanism.Only female warblers perform egg rejection,suggesting that the sex for host egg incubation seems to play an important role in the evolution of egg recognition mechanisms.

A New Zn(Ⅱ) Coordination Polymer Constructed from 4-(1H-pyrazol-3-yl)pyridine as Fluorescent Sensor for Fe^(3+)

A new Zn(Ⅱ) coordination polymer, [Zn(4-PP)(1,4-BDC)?(H_2O)]_n(1, 4-PP = 4-(1 H-pyrazol-3-yl)pyridine, 1,4-H_2BDC = 1,4-benzenedicarboxylic acid), has been synthesized and structurally characterized by single-crystal X-ray diffraction as well as elemental analysis, IR spectra, XRPD and TG. Structural analysis reveals that Zn(Ⅱ) ions are bridged by COO-from 1,4-BDC^(2-)to form a binuclear structure as the second building units(SBUs). Zn_2 clusters can be clarified as 4-connected nodes, so the framework of 1 can be considered as a 2 D(44?62)-sql sheet. Fluorescence measurements show that 1 has highly selective and sensitive detection of Fe^(3+) in water medium.

Design and Self-assembly of a Novel Tetranuclear Zinc(Ⅱ) Complex via Reaction of 1,3-Thiazolidine-2-thione(tzdtH) with Zn(NO_ 3)_ 2

The self-assembly of clusters in inorganic systems is an interesting subject. The self-assembly of big molecules has been well established in biological systems. In addition, the coordination chemistry of metal-sulfur-nitrogen cluster complexes has been a very active and attracting field for many years as a result of the novelty and versatility of the crystal structures and reactivities of such clusters, as well as their potential applications as the models for the active sites in non-heme proteins. At the same time, there is currently considerable interest in the formation of metal complexes with heterocyclic ligands because of the diverse characteristics of ligands and their consequential wide range of applications.

Synthesis and Luminescence Properties of Three High-dimensional Coordination Polymers:Zn(Ⅱ) with Imidazole or Benzimidazole Ligand

A novel 2D coordination polymer [Zn2（bim）4]n（1）（Hbim=benzimidazole） based on dihydrated- [N,N＇-bis（2-aminophenl）-oxalamide]（L1·2H2O） with zinc nitrate has been synthesized. Previously we have synthesized complexes [In：Zn3（im）12]n（2）（Him= imidazole） and [Zn（im）2]n（3） successfully. In complex 1, each Zn（Ⅱ） coordinated with four ligands adopts a distorted tetrahedron coordination mode, and the 2D grid structure is built by the Zn（bim）4 as the secondary building unit（SBU）. The luminescence properties of the three complexes were investigated for the first time. The emissions with maxima for complexes 1, 2 and 3 are at 379, 469 and 392 nm, respectively.

How Confucian Philosophy of Balanced Harmony Promotes World Harmony

Harmony is the general principle for dealing with various social problems and promoting world harmony.China regards“harmony is most precious”as its ultimate value goal.Harmony is the core value and moral sentiment of the Chinese nation and it is the criterion for dealing with the relationships between people,between people and society,and between countries.The principles and methods of harmony should be used to govern a state so that it can be in a state of mutual integration.Harmony is a theoretical prescription for solving many crises and contradictions today.It is the meaning and value of learning and understanding universal rule.Harmony is the core value of the Chinese nation,the noumenon and universal rule of human existence,and the well-being of human existence.Harmony has various levels of expression,and its value is mainly reflected in harmony of oneself,harmony of the people,and harmony of nature.Benevolence is the core value concept of balanced harmony,and the philosophy of balanced harmony is realized through propriety.No matter for the communication between individuals,or the relationships between groups,nations,and countries,harmony is the eternal value pursuit and propriety is its eternal value carrier.

Research Status of Career Identity of Chinese College Students in 2010-2018

This paper sorts out the research on the current college students＇ career identity in China. From the analysis of the number, the object and the content of the researches, expound the significance, the role, the existing problems and the solutions of the college students＇ career idenlity. It is pointed out that there are some problems of college students in China. such as the number of studies are few. the research direction is single, more empirical research and less qualitative research, fewer enforceable schemes etc. Further research can effectively improve the number and qualily ofemploynment of college students, and will also effeciively provide protection for social development.

On Building Practice Teaching Models for Business English Major

Practice teaching is playing a more and more important role in cultivating qualified graduates for the society, Business English combines both English language and business together, and it itself is an application of language. For English major students, schools should innovate their teaching models and improving teaching conditions to help students to get practical knowledge and acquire real skills to be used in real business situations.

The Legal Regulation of the Information Exchange for Trade Association in China

In the modem society where information is efficient, information exchange is an important affair and function of trade association. However, information exchange behaviors of industry association will have double and legal effect on market and competition, which can not only promote the communication among members of the industry to find a solution to the industry benefit maximization, but also can produce inhibition and barriers to competition in the market. So in this paper, the industry association analysis will be made on the pros and cons of the information exchange, and the legislative defects and the insufficiency of information exchange industry association in our country. According to the practice in our country, the author puts forward the system design of our country industry association information exchange behavior.

The Impact of Personalized Learning Path Design on Online Education Platforms on Students’Self-Learning Abilities

The study investigates the impact of personalized learning path design on students’self-learning abilities(SLA)within online education platforms.Employing a mixed-methods approach,the research examines the effectiveness of personalized learning through quantitative surveys and qualitative interviews with a diverse sample of online learners.The findings indicate that personalized learning path design significantly enhances students’self-efficacy,engagement,and satisfaction,leading to improved SLA.The study’s conceptual model and empirical data support the hypothesis that personalization in learning environments fosters self-directed learning skills.The discussion highlights the implications for educational practice,emphasizing the need for online platforms to prioritize personalization and for educators to adapt their teaching methods to support diverse learner needs.The research also acknowledges limitations and suggests future directions,including longitudinal studies and expanded participant demographics.The study concludes that personalized learning path design is a promising strategy for online education platforms to empower learners and promote lifelong learning skills.

Ethical Analysis of Ethical Issues and Countermeasures in Education in the Era of Artificial Intelligence

The integration of artificial intelligence(AI)in education has revolutionized teaching and learning methodologies,offering personalized experiences and efficient resource management.However,this technological advancement has also surfaced a plethora of ethical concerns that necessitate careful consideration.This paper delves into the ethical issues arising from AI applications in education,such as data privacy,algorithmic bias,educational equity,and the evolving role of teachers.Through a comprehensive analysis,we identify the challenges and propose strategic countermeasures to mitigate these ethical dilemmas.Case studies from both domestic and international contexts are employed to illustrate real-world applications and the associated ethical decision-making processes.The paper concludes with a summary of findings,policy recommendations,and an outlook on future research directions,emphasizing the need for a balanced approach that respects both technological innovation and ethical standards in educational AI deployment.

Experimental Research on Reverse Teaching in College Football Instruction

In higher education,football education faces challenges such as low student engagement and suboptimal teaching methods.This study explores the effectiveness of flipped classroom teaching in college-level football education.Flipped classroom teaching reverses traditional methods,emphasizing pre-class independent study and in-class interactions.Through experimental research,we assess its impact on student learning experiences and outcomes,aiming to enhance the quality of football education.

Emission-tunable Ba_(2)Y_(1-x)Sc_(x)NbO_(6):Bi^(3+)(0≤x≤1.0)phosphors for white LEDs

Here,we report a series of Bi^(3+)-doped Ba_(2)Y_(1-x)Sc_(x)NbO_(6)(0≤x≤1.0 mol)phosphors by using the traditional high temperature solid-state reaction.To achieve the structural and photoluminescent(PL)information,several experimental characterizations and theoretical calculations were carried out,including X-ray diffraction(XRD),Rietveld refinement,UV-visible diffuse reflectance and PL spectra,temperature dependent PL spectra,and density functional theo retical(DFT)calculations.The XRD results show that the Bi^(3+)-doped Ba_(2)Y_(1-x)Sc_(x)NbO_(6)samples belong to the double-perovskite phase with a cubic space group of Fm3 m,and the diffraction positions shift toward high diffraction angle when the larger Y^(3+)ions are gradually replaced by the smaller Sc^(3+)ions.In addition,the refined XRD findings show that the Bi^(3+)ions tend to substitute the Y^(3+)and Sc^(3+)sites in the Bi^(3+)-doped Ba_(2)Y_(1-x)Sc_(x)NbO_(6)0<x<1.0 mol)solid solutions.The PL spectra show that the emission positions of the solid solution samples tune from446 to 497 nm with the increase of Sc^(3+) content,which can be attributed to the modification of crystal field strength around Bi^(3+)ions.Moreover,there is energy transfer from the Ba_(2)YNbO_(6)host to Bi^(3+)ions,which is dominated by a resonant type via a dipole-quadrupole(d-q)interaction.The Ba_(2)Y_(0.6)Sc_(0.4)NbO_(6):0.02 molBi^(3+)shows the strongest PL intensity under 365 nm excitation,with the best quantum efficiency(QE)of 68%,and it keeps 60%of the room temperature emission intensity when the temperature increases to 150℃,meaning that the Ba_(2)Y_(0.6)Sc_(0.4)NbO_(6):Bi^(3+)features excellent thermal quenching of luminescence.By combining this optimal sample with a commercial red-emitting Sr_(2)Si_(5)N_(8):Eu^(2+)phosphor,and a commercial 365 nm UV LED chip,a white LED device,with the color temperature(CT)of 3678 K,color rendering index(CRI)of 67.9,and CIE coordinates at(0.371,0.376),is achieved.

Responses of benthic insect communities to effluent from the abandoned Ferris-Haggarty copper mine in southeast Wyoming,USA

Six criteria were used to evaluate 12 metrics for their sensitivity to effluent flowing from the Ferris-Haggarty copper mine into Haggarty Creek and then into Battle Creek West Fork.Through the evaluation process,we found that the Shannon-Wiener index,the random runs value,and Ephemeroptera taxa richness appeared to best reflect the impacts that have occurred in both Haggarty Creek and Battle Creek West Fork.In addition,Ephemeroptera/Plecoptera/Trichoptera taxa richness,total taxa richness,and Plecoptera taxa richness,were useful in reflecting those impacts.In contrast,we found that the abundance ratios,the Hilsenhoff Biotic Index,as well as Trichoptera taxa richness,did not reflect the impacts that occurred in Haggarty Creek and Battle Creek West Fork.Finally,this study provided information about the benthic insect communities that are present in the impacted reaches of Haggarty Creek.Such information is needed to assess the potential of those reaches as habitat for the Colorado River cutthroat trout,Oncorhynchus clarki pleuriticus,which is a species of special concern to the Wyoming Department of Game and Fish.

Transformations of multilevel coherent states under coherence-preserving operations

Quantum coherence,emerging from the"superposition"of quantum states,is widely used in various information processing tasks.Recently,the resource theory of multilevel quantum coherence is attracting substantial attention.In this paper,we mainly study the transformations of resource pure states via free operations in the theoretical framework for multilevel coherence.We prove that any two multilevel coherent resource pure states can be interconverted with a nonzero probability via a completely positive and trace non-increasing k-coherence-preserving map.Meanwhile,we present the condition of the interconversions of two multilevel coherent resource pure states under k-coherence-preserving operations.In addition,we obtain that in the resource-theoretic framework of multilevel coherence,no resource state is isolated,that is,given a multilevel coherent pure state|ψ>,there exists another multilevel coherent pure state|Φ>and a k-coherence-preserving operation∧k,such that∧k(|Φ>)=|ψ>.

Isatin hybrids and their anti-tuberculosis activity

Tuberculosis（TB） is one of the most common and even fatal infectious diseases known to mankind.Millions of new cases are reported every year over the world,and one-third of the world＇s population is potentially infected with mycobacteria tuberculosis（MTB）.Research to develop novel anti-TB drugs led to the identification of several isatin-based antimycobacterial agents,among which a number of potential candidates displayed excellent antimycobacterial activity and were found to be free of cytotoxicity.This review outlines the advances in the application of isatin hybrids as antimycobacterial agents and the critical aspects of design and structure-activity relationship of these derivatives.

Minimum distances of three families of low-density parity-check codes based on finite geometries

Three families of low-density parity-check （LDPC） codes are constructed based on the totally isotropic subspaces of symplectic, unitary, and orthogonal spaces over finite fields, respectively. The minimum distances of the three families of LDPC codes in some special cases are settled.

Classification and applied uses of Bryaceae sensu lato(Musci) in China

The Bryaceae is a large, cosmopolitan, taxonomically difficult moss family. Recent studies based on molecular data alone or in combination with morphological data have greatly changed the understanding of phylogenetic relationships in the Bryaceae s.l. and indicate that the Bryaceae is not monophyletic. Based on phylogenetic analyses of sequence data for four cpDNA regions and morphological data, we revise the traditional Bryaceae in China and transfer six genera to other families. The Mielichhoferiaceae was redefined previously by Hill et al. based on the presence of much-branched stems, apparently lateral gametangia, Pohlia-like leaves, and a more-or-less reduced peristome. Five genera of Mielichhoferiaceae are present in China: Mielichhoferia(four species), Pohlia(27 species, two varieties), Pseudopohlia(one species), Epipterygium(two species), and Synthetodontium(one species). The genera Orthodontium and Leptobryum are transferred from the Bryaceae s.l. to Orthodontiaceae and Meesiaceae, respectively. Members of the recircumscribed Bryaceae belong to five genera: Anomobryum(five species), Brachymenium(14 species), Bryum(54 species, two varieties), Plagiobryum(three species), and Rhodobryum(four species). Bryaceae diversity is high in China. The species have potential uses in medicine, landscaping, environmental protection, and other fields. Rhodobryum roseum(Hedw.) Limpr., Bryum argenteum Hedw., and Rhodobryum giganteum(Schw gr.) Paris have long been used to cure cardiovascular disease in China. Some bioactive compounds will be leading compounds for the future design of novel drugs. In recent years, many species of Bryaceae have been used for landscaping. Bryum spp. are the dominant biotic species in biological soil crusts, which serve important ecological protective functions.

Synthesis, Structures and Properties of Two Complexes Based on Benzimidazole or Benzothiazole Ligand

Two complexes,Co（Hbim）2（NCS）2（Hbim=benzimidazole）（1） and [Cu（Hbzt）SCN]n（Hbzt=benzothiazole） （2） were synthesized by the same synthesis method and characterized by elemental analysis,infrared spectroscopy（IR）,thermogravimetric analysis（TGA）,X-ray powder diffraction（XRPD） and single-crystal X-ray diffraction.The results from the single-crystal X-ray diffraction indicate that complex 1 is zero-dimensional（0D） framework and complex 2 is 2-dimensional（2D） framework.In complex 2,the 3-dimensional（3D） supermolecular architecture was built up by means of π-π stacking interaction,and two helical chains existed in its structure.The luminescence properties and the magnetic properties of the two complexes were investigated.