Primary malignant circulating prostate cells(CPCs)are those detected in blood before definitive treatment for prostate cancer.CPCs can be detected in men with benign prostate disease;however,some methods to distinguis...Primary malignant circulating prostate cells(CPCs)are those detected in blood before definitive treatment for prostate cancer.CPCs can be detected in men with benign prostate disease;however,some methods to distinguish between benign and malignant prostate cells have to be validated.This study presents a review of the subject,including theoretical considerations for the selection of markers to detect them,the different methods used,and the utility of their detection in identifying men with prostate cancer and as a prognostic factor.展开更多
文摘Primary malignant circulating prostate cells(CPCs)are those detected in blood before definitive treatment for prostate cancer.CPCs can be detected in men with benign prostate disease;however,some methods to distinguish between benign and malignant prostate cells have to be validated.This study presents a review of the subject,including theoretical considerations for the selection of markers to detect them,the different methods used,and the utility of their detection in identifying men with prostate cancer and as a prognostic factor.
