Differences of five blood-activating and stasis-resolving prescriptions on endothelial cell function in rabbits with blood stasis syndrome

Objective To observe the mechanism and different effects of five blood-activating and stasis resolving prescriptions on endothelial cell function in rabbit with blood stasis syndrome.Methods Seventy New Zealand rabbits were selected,6 of them were served as control group,and the remaining 64 were given hunger+hyperlipidemia+adrenaline method to establish blood stasis syndrome.The successfully established model rabbits were divided into model group (n=9).

Mechanism studyof Conggan Zhixin decoction for ischemia/reperfusion injury of myocardial cells based on ferritinophagy

Objective To investigate the mechanism of improving myocardial ischemia/reperfusion injury using Conggan Zhixin Decoction(CGZXD).Methods Fifty SD rats were randomly divided into 5 groups:sham-operated group,model group,CGZXD group,Shexiang Baoxin Pill(SBP)group,Diltiazem group,with 10 rats in each group.A rat model of myocardial ischemia/reperfusion injury was prepared.The intervention group was given CCZXD[5.32 g/(kg·d)],SBP[10.27 mg/(kg:d)],and diltiazem[6.86 mg/(kg·d)]by gavage respectively.The sham-operated group and model group were given equal amounts of physiological saline by gavage.After 14 days of intervention,samples were taken,and the morphology of myocardial tissuewas observed using HE staining.

Qingwen Baidu decoction regulated mouse alveolar macrophages autophagy to reduce sepsis induced lung injury via inhibiting TLR4/NF-κB signaling pathway:an experimental study

Objective To study the mechanism of Qingwen Baidu Decoction(QWBDD)in regulating autophagy of mouse alveolar macrophages and alleviating sepsis induced lung injury.Methods A total of 60 C57BL/6 mice were divided into blank group,model group,low,medium,high dose QWBDD groups.

Effects of electroacupuncture on NLRP3 inflammasome and pyroptosis protein GSDMD in uterine tissue in rats with primary dysmenorrhea

Objective To observe the effects of electroacupuncture(EA) on NLRP3 inflammasome and its downstream protein gastermin D(GSDMD)in rats with primary dysmenorrhea(PDM),and to explore the potential mechanism of EA on the treatment of PDM.Methods Forty healthy female SD rats without pregnancy were randomly divided into a control group.

Effects of electroacupuncture at"Siguan"points on the expression of colonic 5-hydroxytryptamine and fecal short-chain fatty acids in rats with post-stroke depression

Objective To observe the effects of electroacupuncture at"Siguan"points on behavior,colonic 5-hydroxytryptamine(5-HT)and fecal short-chain fatty acids(SCFAs)in rats with post-stroke depression(PSD),and explore the effectmechanism of electroacupuncture at Siguan points on PSD.Methods Fifty SD rats were randomly divided into a sham-operation group,a stroke group,a PSD group,a drug group and an electroacupuncture group,with 10 rats in each group.

Clinical observation on Tongdu Tiaoqi acupuncture combined with warming acupuncture for postoperative urinary retention

Objective Tongdu Tiaoqi acupuncture (acupuncture for unblocking governor vessel and regulating qi) combined with warming acupuncture,Tongdu Tiaoqi acupuncture, abdominal moxibustion and oral tamsulosin hydrochloride sustained release capsule on postoperative urinary retention.Methods A total of 120 patients with postoperative urinary retention were randomized into an acupuncture-moxibustion group.