Epigallocatechin-3-gallate （EGCG）, a naturally occurring compound in green tea, has been widely used as an antioxidant agent. In the present study, model rats with acute spinal cord injury were intraperitoneally inj...Epigallocatechin-3-gallate （EGCG）, a naturally occurring compound in green tea, has been widely used as an antioxidant agent. In the present study, model rats with acute spinal cord injury were intraperitoneally injected with 25, 50, and 100 mg/kg EGCG, and spinal cord ultrastructure, oxidative stress reaction, inflammatory factors, and apoptosis-associated gene expression were observed. Results showed that EGCG attenuated neuronal and axonal injury 24 hours post injury. It also decreased serum intedeukin-113, tumor necrosis factor-a, and intercellular adhesion molecule-1 release, and decreased apoptosis-associated gene expression. Furthermore, it increased the level of the superoxide anion （O2-）, superoxide dismutase, and B-cell lymphoma/leukemia-2, and reduced malondialdehyde levels. Furthermore, it reduced the expression of the pro-apoptotic protein Bax. Noticeably, EGCG at the 100 mg/kg dosage exhibited similar effects as methylprednisolone sodium succinate, which has been frequently used for clinical acute spinal cord injury. The results demonstrated that EGCG can significantly inhibit inflammation, suppress oxidation, and reduce apoptosis in acute spinal cord injury.展开更多
The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GAB...The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GABA-containing neurons were found over all layers and all were nonpyramidal cells.The laminar distribution of GABA-containing ne-urons was not even between different layers,density in laye Ⅱ was prominently higher than any other layers,density in layer Ⅲ and layer Ⅳ was higher than that in layer V and Ⅵ.展开更多
This study aims to construct the skeletal system of children at different ages through digital modeling techniques,explore the law of morphological development of childen's skeletal system,so as to provide a refer...This study aims to construct the skeletal system of children at different ages through digital modeling techniques,explore the law of morphological development of childen's skeletal system,so as to provide a reference for the study of children's bone development and digital anatomy.In this study,12 normal boys were selected from 6 age stages(0-6 months,6-12 months,1-3 years old,3-5 years old,5-7 years old,7-10 years old).All patients underwent CT plain scan with a slice thickness of 0.625 mm.The collected CT data was imported into Mimics 19.0 software for three dimensional reconstruction of children's whole body bones.3D printing of children's bone model was used to construct children's bone system.T wo dissected bone specimens were randomly selected and compared with 3D printed models for specific bony landmarks to verify the accuracy of modeling.展开更多
The purpose of this study is to research the difference of lesion volume and its constituent ratio of lung volume of Novel Coronavirus Pneumonia(NCP)between male and female by digital technology.In this study,the CT i...The purpose of this study is to research the difference of lesion volume and its constituent ratio of lung volume of Novel Coronavirus Pneumonia(NCP)between male and female by digital technology.In this study,the CT imaging data and clinical data of 40 NCP patients in Huaihua were collected and divided into two groups:male(n=22)and female(n=18)according to gender.展开更多
A number of fluorescent retrograde neuronal tracers have been introduced recently. However, they all have some shortcomings. We have found that a home-made anion fluorescent dye, Titan Yellow (TY; CP; Ting Xiu, Shangh...A number of fluorescent retrograde neuronal tracers have been introduced recently. However, they all have some shortcomings. We have found that a home-made anion fluorescent dye, Titan Yellow (TY; CP; Ting Xiu, Shanghai), was transported retrogradely through axons to their parent cell bodies, with neither migration out of labeled neurons nor tissue damage. Twenty-seven adults albino rats were used in this study.展开更多
It has been reported that substances cross-reactive with ABH(O) or Lewis blood group antigens have been detected in plants, microbes, animals and parasites. Substances cross-reactive with ABH(O)blood group or bacteria...It has been reported that substances cross-reactive with ABH(O) or Lewis blood group antigens have been detected in plants, microbes, animals and parasites. Substances cross-reactive with ABH(O)blood group or bacterial antigens have also been detected in Chinese medicinal herbs; in 2 kinds of herbs, namely, Leonurus sibiricus L. and Carthamus tinctorius L., Le^a-like substances cross-reactive with展开更多
Injectio Zhishi （枳实） as an extraction from Zhishi （Citrus Aurantium L.） has proved of its marked pressor and cardiac inotropic effects. Its active principles as isolated were identified as synephrine and N-methy...Injectio Zhishi （枳实） as an extraction from Zhishi （Citrus Aurantium L.） has proved of its marked pressor and cardiac inotropic effects. Its active principles as isolated were identified as synephrine and N-methyltyramine, the former acting directly on the adrenergic receptors while the latter indirectly by releasing catecholamine in the body(1,2)Its effectiveness and obvious advantages in the treatment of shock of various etiology have been proved by clinical applications(3,4)But according to experimental observations, with large dosages it occasionally causes arrhythmia such展开更多
文摘Epigallocatechin-3-gallate （EGCG）, a naturally occurring compound in green tea, has been widely used as an antioxidant agent. In the present study, model rats with acute spinal cord injury were intraperitoneally injected with 25, 50, and 100 mg/kg EGCG, and spinal cord ultrastructure, oxidative stress reaction, inflammatory factors, and apoptosis-associated gene expression were observed. Results showed that EGCG attenuated neuronal and axonal injury 24 hours post injury. It also decreased serum intedeukin-113, tumor necrosis factor-a, and intercellular adhesion molecule-1 release, and decreased apoptosis-associated gene expression. Furthermore, it increased the level of the superoxide anion （O2-）, superoxide dismutase, and B-cell lymphoma/leukemia-2, and reduced malondialdehyde levels. Furthermore, it reduced the expression of the pro-apoptotic protein Bax. Noticeably, EGCG at the 100 mg/kg dosage exhibited similar effects as methylprednisolone sodium succinate, which has been frequently used for clinical acute spinal cord injury. The results demonstrated that EGCG can significantly inhibit inflammation, suppress oxidation, and reduce apoptosis in acute spinal cord injury.
文摘The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GABA-containing neurons were found over all layers and all were nonpyramidal cells.The laminar distribution of GABA-containing ne-urons was not even between different layers,density in laye Ⅱ was prominently higher than any other layers,density in layer Ⅲ and layer Ⅳ was higher than that in layer V and Ⅵ.
文摘This study aims to construct the skeletal system of children at different ages through digital modeling techniques,explore the law of morphological development of childen's skeletal system,so as to provide a reference for the study of children's bone development and digital anatomy.In this study,12 normal boys were selected from 6 age stages(0-6 months,6-12 months,1-3 years old,3-5 years old,5-7 years old,7-10 years old).All patients underwent CT plain scan with a slice thickness of 0.625 mm.The collected CT data was imported into Mimics 19.0 software for three dimensional reconstruction of children's whole body bones.3D printing of children's bone model was used to construct children's bone system.T wo dissected bone specimens were randomly selected and compared with 3D printed models for specific bony landmarks to verify the accuracy of modeling.
文摘The purpose of this study is to research the difference of lesion volume and its constituent ratio of lung volume of Novel Coronavirus Pneumonia(NCP)between male and female by digital technology.In this study,the CT imaging data and clinical data of 40 NCP patients in Huaihua were collected and divided into two groups:male(n=22)and female(n=18)according to gender.
文摘A number of fluorescent retrograde neuronal tracers have been introduced recently. However, they all have some shortcomings. We have found that a home-made anion fluorescent dye, Titan Yellow (TY; CP; Ting Xiu, Shanghai), was transported retrogradely through axons to their parent cell bodies, with neither migration out of labeled neurons nor tissue damage. Twenty-seven adults albino rats were used in this study.
文摘It has been reported that substances cross-reactive with ABH(O) or Lewis blood group antigens have been detected in plants, microbes, animals and parasites. Substances cross-reactive with ABH(O)blood group or bacterial antigens have also been detected in Chinese medicinal herbs; in 2 kinds of herbs, namely, Leonurus sibiricus L. and Carthamus tinctorius L., Le^a-like substances cross-reactive with
文摘Injectio Zhishi （枳实） as an extraction from Zhishi （Citrus Aurantium L.） has proved of its marked pressor and cardiac inotropic effects. Its active principles as isolated were identified as synephrine and N-methyltyramine, the former acting directly on the adrenergic receptors while the latter indirectly by releasing catecholamine in the body(1,2)Its effectiveness and obvious advantages in the treatment of shock of various etiology have been proved by clinical applications(3,4)But according to experimental observations, with large dosages it occasionally causes arrhythmia such
