Chiral extractant plays a key role in chiral extraction,and considerable efforts have been undertaken for the development of new and efficient chiral extractants in recent years.This work demonstrated for the first ti...Chiral extractant plays a key role in chiral extraction,and considerable efforts have been undertaken for the development of new and efficient chiral extractants in recent years.This work demonstrated for the first time that chiral ferrocenyl diphosphine ligand(Mandyphos-Pd)had considerable ability to enantioseparate 3-Chlorophenylglycine enantiomers with separation factor(α)of 2.64.Mandyphos-Pd concentration and pH had significant influences on enantioselectivity,while operating temperature showed less influence.The extraction experiments can be performed at room temperature(20℃)which had the advantage of energy saving.After optimization,the highest performance factor(pf,0.08376)was obtained at the condition of pH 7.8 and Mandyphos-Pd concentration 1.2 mmol·L^(-1).According to the experimental results,the possible recognition mechanism was discussed.展开更多
In this review,the recent development in transition metal catalyzed cross coupling of nitroarenes was highlighted.Firstly,development of transition metal catalyzed cross coupling was simply introduced.After presenting...In this review,the recent development in transition metal catalyzed cross coupling of nitroarenes was highlighted.Firstly,development of transition metal catalyzed cross coupling was simply introduced.After presenting the advantages of nitroarenes,transition metal catalyzed cross coupling using nitroarenes as electrophilic coupling partners was classified and introduced in detail.Based on different chemical bonds such as C–O,C–S,C-C and C–N bonds constructed,different kinds cross coupling of nitroarenes would be highlighted and the plausible reaction mechanism would be presented if available.展开更多
Safely and highly selective acetylene(C_(2)H_(2))capture is a great challenge,because of its highly explosive nature,as well as its nearly similar molecule size and boiling point toward the main impurity of carbon dio...Safely and highly selective acetylene(C_(2)H_(2))capture is a great challenge,because of its highly explosive nature,as well as its nearly similar molecule size and boiling point toward the main impurity of carbon dioxide(CO_(2)).Adsorption separation has shown a promising future.Herein,a new nanoporous coordination polymer(PCP)adsorbent with fixed and free Cu ions(termed NTU-66-Cu)was prepared through post-synthetic approach via cation exchanging from the pristine NTU-66,an anionic framework with new 3,4,6-c topology and two kinds of cages.The NTU-66-Cu shows significantly improved C_(2)H_(2)/CO_(2)selectivity from 6 to 32(v/v:1/1)or 4 to 4_(2)(v/v:1/4)at low pressure under 298 K,along with enhanced C_(2)H_(2)capacity(from 89.22to 111.53 cm^(3)·g^(-1)).More importantly,this observation was further validated by density functional theory(DFT)calculations and breakthrough experiments under continuous and dynamic conditions.Further,the excellent chemical stability enables this adsorbent to achieve recycle C_(2)H_(2)/CO_(2)separation without loss of C_(2)H_(2)capacity.展开更多
Directly monitoring mitophagy-specific viscosity dynamic in living cells is of great significance but remains challenging.Herein,this study reported a novel mitochondria-targeted fluorescent probe DPACDY based on vibr...Directly monitoring mitophagy-specific viscosity dynamic in living cells is of great significance but remains challenging.Herein,this study reported a novel mitochondria-targeted fluorescent probe DPACDY based on vibration-induced emission(VIE)for monitoring viscosity changes during mitochondrial autophagy.This probe contained N,N’-diphenyl-dihydrodibenzo[a,c]phenazine(DPAC)as the VIE core and two positively charged pyridinium moieties for mitochondria anchoring.As the ambient viscosity increased,the vibration of DPAC-DY could be hindered,and subsequently resulting in the enhancement of fluorescence emission.In vitro and intracellular experiments indicated that the probe DPAC-DY showed highly sensitive response to viscosity due to VIE mechanism.Importantly,by virtue of this probe,in situ and real-time visualization of the specific viscosity dynamics during the mitochondrial autophagy process was achieved.Thus,this work provides a novel strategy for VIE-based viscosity response sensors applied to specific organelles and offers a platform for in-depth study of mitochondrial viscosity-related diseases.展开更多
In this review,the recent development about using DESs as green solvents in transition metal catalyzed organic reactions was highlighted.Firstly,the development of DESs was simply introduced.After presenting the advan...In this review,the recent development about using DESs as green solvents in transition metal catalyzed organic reactions was highlighted.Firstly,the development of DESs was simply introduced.After presenting the advantages of DESs,transition metals catalyzed organic reactions using DESs as green solvents were classified and introduced in detail.Different transition metals such as Au,metal impregnated on magnetite,Pd and Ru catalyzed organic reactions proceeded smoothly in DESs and gave corresponding products in good yields.And in some cases,the catalytic systems could be recycled up to several times without any decrease in activity.展开更多
基金This work was financially supported by National Natural Science Foundation of China(Grant No.51703060)Hunan Provincial Innovation Foundation for Postgraduate(Grant No.CX2018B673).
文摘Chiral extractant plays a key role in chiral extraction,and considerable efforts have been undertaken for the development of new and efficient chiral extractants in recent years.This work demonstrated for the first time that chiral ferrocenyl diphosphine ligand(Mandyphos-Pd)had considerable ability to enantioseparate 3-Chlorophenylglycine enantiomers with separation factor(α)of 2.64.Mandyphos-Pd concentration and pH had significant influences on enantioselectivity,while operating temperature showed less influence.The extraction experiments can be performed at room temperature(20℃)which had the advantage of energy saving.After optimization,the highest performance factor(pf,0.08376)was obtained at the condition of pH 7.8 and Mandyphos-Pd concentration 1.2 mmol·L^(-1).According to the experimental results,the possible recognition mechanism was discussed.
基金Project(51202066)supported by the National Natural Science Foundation of ChinaProject(NCET-13-0784)supported by the Program for New Century Excellent Talents in University of China。
基金the National Natural Science Foundation of China (Nos. 21802040, 21877034)the Natural Science Fund Youth Project of Hunan Province (No. 2018JJ3145)+1 种基金the General project of Hunan Education Department (No. 17C0629)the Open Foundation of Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education, Hunan University of Science and Technology (No. E21843) for financial support
文摘In this review,the recent development in transition metal catalyzed cross coupling of nitroarenes was highlighted.Firstly,development of transition metal catalyzed cross coupling was simply introduced.After presenting the advantages of nitroarenes,transition metal catalyzed cross coupling using nitroarenes as electrophilic coupling partners was classified and introduced in detail.Based on different chemical bonds such as C–O,C–S,C-C and C–N bonds constructed,different kinds cross coupling of nitroarenes would be highlighted and the plausible reaction mechanism would be presented if available.
基金the National Natural Science Foundation of China(No.21671102,21973029)the Innovative Research Team Program by the Ministry of Education of China(No.IRT-17R54)+2 种基金the Hunan Provincial Natural Science Foundation of China(No.2020JJ4290)the Young and Middle-aged Academic Leader of Jiangsu Provincial Blue Project,the Six Talent Peaks Project in Jiangsu Province(No.JY-030)the State Key Laboratory of Materials-Oriented Chemical Engineering(No.ZK201803).We also thank Prof.M.O’Keeffe and Prof.M.Li for valuable suggestion on topology analysis.
文摘Safely and highly selective acetylene(C_(2)H_(2))capture is a great challenge,because of its highly explosive nature,as well as its nearly similar molecule size and boiling point toward the main impurity of carbon dioxide(CO_(2)).Adsorption separation has shown a promising future.Herein,a new nanoporous coordination polymer(PCP)adsorbent with fixed and free Cu ions(termed NTU-66-Cu)was prepared through post-synthetic approach via cation exchanging from the pristine NTU-66,an anionic framework with new 3,4,6-c topology and two kinds of cages.The NTU-66-Cu shows significantly improved C_(2)H_(2)/CO_(2)selectivity from 6 to 32(v/v:1/1)or 4 to 4_(2)(v/v:1/4)at low pressure under 298 K,along with enhanced C_(2)H_(2)capacity(from 89.22to 111.53 cm^(3)·g^(-1)).More importantly,this observation was further validated by density functional theory(DFT)calculations and breakthrough experiments under continuous and dynamic conditions.Further,the excellent chemical stability enables this adsorbent to achieve recycle C_(2)H_(2)/CO_(2)separation without loss of C_(2)H_(2)capacity.
基金supported by the National Natural Science Foundation of China(NSFC,52273206,52173278,and 51833011)Hunan Provincial Natural Science Foundation of China(2021JJ10029,2020JJ3021,and 2021JJ40192)+1 种基金the Open Fund of Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers(E22125)the Science and Technology Innovation Program of Hunan Province(2022RC1075 and 2021RC5028)。
基金the National Natural Science Foundation of China(Nos.81672508 and 61601218)Key University Science Research Project of Jiangsu Province(No.19KJA520005)+3 种基金Jiangsu Provincial Foundation for Distinguished Young Scholars(No.BK20170041)Natural Science Basic Research Program of Shaanxi(No.2019JM-016)China-Sweden Joint Mobility Project(No.51811530018)Fundamental Research Funds for the Central Universities。
文摘Directly monitoring mitophagy-specific viscosity dynamic in living cells is of great significance but remains challenging.Herein,this study reported a novel mitochondria-targeted fluorescent probe DPACDY based on vibration-induced emission(VIE)for monitoring viscosity changes during mitochondrial autophagy.This probe contained N,N’-diphenyl-dihydrodibenzo[a,c]phenazine(DPAC)as the VIE core and two positively charged pyridinium moieties for mitochondria anchoring.As the ambient viscosity increased,the vibration of DPAC-DY could be hindered,and subsequently resulting in the enhancement of fluorescence emission.In vitro and intracellular experiments indicated that the probe DPAC-DY showed highly sensitive response to viscosity due to VIE mechanism.Importantly,by virtue of this probe,in situ and real-time visualization of the specific viscosity dynamics during the mitochondrial autophagy process was achieved.Thus,this work provides a novel strategy for VIE-based viscosity response sensors applied to specific organelles and offers a platform for in-depth study of mitochondrial viscosity-related diseases.
基金the National Natural Science Foundation of China (Nos.21802040,21877034)the Natural Science Fund Youth Project of Hunan Province (No.2018JJ3145)+1 种基金the General project of Hunan Education Department(No. 17C0629)the Open Foundation of Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education,Hunan University of Science and Technology(No. E21843) for financial support
文摘In this review,the recent development about using DESs as green solvents in transition metal catalyzed organic reactions was highlighted.Firstly,the development of DESs was simply introduced.After presenting the advantages of DESs,transition metals catalyzed organic reactions using DESs as green solvents were classified and introduced in detail.Different transition metals such as Au,metal impregnated on magnetite,Pd and Ru catalyzed organic reactions proceeded smoothly in DESs and gave corresponding products in good yields.And in some cases,the catalytic systems could be recycled up to several times without any decrease in activity.
