Malaria is a mosquito-borne disease caused by protozoan parasites of Plasmodium genus,inflicting health of human living in tropical and subtropical regions of the globe since time immemorial.
Female mosquitoes of several species require blood from warmblooded animals,including humans for the purpose of reproduction.In this process,several microbes residing in the salivary gland and midgut of mosquitoes als...Female mosquitoes of several species require blood from warmblooded animals,including humans for the purpose of reproduction.In this process,several microbes residing in the salivary gland and midgut of mosquitoes also get transferred from one human individual to the other–a traditional model by which many vector-borne diseases(VBDs)get transmitted in the population through mosquitoes belonging to Anopheles,Aedes,Culex and other genera.展开更多
Japanese encephalitis(JE),one of the major viral encephalitides,is caused by Flavivirus circulating in rural areas of Asia and Western Pacific regions[1]and is a neglected tropical viral disease due to its endemicity[...Japanese encephalitis(JE),one of the major viral encephalitides,is caused by Flavivirus circulating in rural areas of Asia and Western Pacific regions[1]and is a neglected tropical viral disease due to its endemicity[2].The culicine mosquitoes,mainly of Culex tritaeniorhynchus and Culex vishnui group,are the vectors of JE virus(JEV)[1].Being a neurologic infection,JE manifests with a set of serious symptoms leading to death in many cases and/or change in behaviour of the patients leading to permanent disability[3].展开更多
Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis(TB)in endemic regions including India,which has contributed the most to global TB burden.W...Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis(TB)in endemic regions including India,which has contributed the most to global TB burden.We argue here that a personalized medicine approach,to start with the N-acetyl transferase-2–isoniazid(NAT2–INH)model,could be a step forward in dealing with both these limitations in controlling TB in India.展开更多
文摘Malaria is a mosquito-borne disease caused by protozoan parasites of Plasmodium genus,inflicting health of human living in tropical and subtropical regions of the globe since time immemorial.
文摘Female mosquitoes of several species require blood from warmblooded animals,including humans for the purpose of reproduction.In this process,several microbes residing in the salivary gland and midgut of mosquitoes also get transferred from one human individual to the other–a traditional model by which many vector-borne diseases(VBDs)get transmitted in the population through mosquitoes belonging to Anopheles,Aedes,Culex and other genera.
文摘Japanese encephalitis(JE),one of the major viral encephalitides,is caused by Flavivirus circulating in rural areas of Asia and Western Pacific regions[1]and is a neglected tropical viral disease due to its endemicity[2].The culicine mosquitoes,mainly of Culex tritaeniorhynchus and Culex vishnui group,are the vectors of JE virus(JEV)[1].Being a neurologic infection,JE manifests with a set of serious symptoms leading to death in many cases and/or change in behaviour of the patients leading to permanent disability[3].
文摘Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis(TB)in endemic regions including India,which has contributed the most to global TB burden.We argue here that a personalized medicine approach,to start with the N-acetyl transferase-2–isoniazid(NAT2–INH)model,could be a step forward in dealing with both these limitations in controlling TB in India.
