ICSED (Improved Cluster Shade Edge Detection) algorithm and other various methods to accurately and efficiently detect edges on satellite data are presented. Error rate criterion is used to statistically evaluate the ...ICSED (Improved Cluster Shade Edge Detection) algorithm and other various methods to accurately and efficiently detect edges on satellite data are presented. Error rate criterion is used to statistically evaluate the performances of these methods in detecting oceanic features for both noise free and noise contaminated AVHRR (Advanced Very High Resolution Radiometer) IR image with Kuroshio. Also, practical experiments in detecting the eddy of Kuroshio with these methods are carried out for comparison. Results show that the ICSED algorithm has more advantages than other methods in detecting mesoscale features of ocean. Finally, the effectiveness of window size of ICSED method to oceanic features detection is quantitatively discussed.展开更多
It is difficult to identify suspected cases of atypical patients with coronavirus disease 2019(COVID-19),and data on severe or critical patients are scanty.This retrospective study presents the clinical,laboratory,and...It is difficult to identify suspected cases of atypical patients with coronavirus disease 2019(COVID-19),and data on severe or critical patients are scanty.This retrospective study presents the clinical,laboratory,and radiological profiles,treatments,and outcomes of atypical COVID-19 patients without respiratory symptoms or fever at onset.The study examined ten atypical patients out of 909 severe or critical patients diagnosed with COVID-19 in Wuhan Union Hospital West Campus between 25 January 2020 and 10 February 2020.Data were obtained from the electronic medical records of severe or critical patients without respiratory symptoms or fever at onset.Outcomes were followed up to discharge or death.Among 943 COVID-19 patients,909(96.4%)were severe or critical type.Of the severe or critical patients,ten(1.1%)presented without respiratory symptoms or fever at admission.The median age of the ten participants was 63 years(interquartile range(IQR):57–72),and seven participants were men.The median time from symptom onset to admission was 14 d(IQR:7–20).Eight of the ten patients had chronic diseases.The patients had fatigue(n=5),headache or dizziness(n=4),diarrhea(n=5),anorexia(n=3),nausea or vomiting(n=3),and eye discomfort(n=1).Four patients were found to have lymphopenia.Imaging examination revealed that nine patients had bilateral pneumonia and one had unilateral pneumonia.Eventually,two patients died and eight were discharged.In the discharged patients,the median time from admission to discharge lasted 24 d(IQR:13–43).In summary,some severe or critical COVID-19 patients were found to have no respiratory symptoms or fever at onset.All such atypical cases should be identified and quarantined as early as possible,since they tend to have a prolonged hospital stay or fatal outcomes.Chest computed tomography(CT)scan and nucleic acid detection should be performed immediately on close contacts of COVID-19 patients to screen out those with atypical infections,even if the contacts present without respiratory symptoms or fever at onset.展开更多
Utilizing aircraft sounding data collected from the Surface Heat Budget of the Arctic Ocean (SHEBA, 1998) campaign, the authors evaluated commonly-used profile methods for Arctic ABL height estimation by validating ag...Utilizing aircraft sounding data collected from the Surface Heat Budget of the Arctic Ocean (SHEBA, 1998) campaign, the authors evaluated commonly-used profile methods for Arctic ABL height estimation by validating against the'true'ABL height from aircraft sounding profiles, where ABL height is defined as the top of the layer with significant turbulence. Furthermore, the best performing method was used to estimate ABL height from the one-year GPS soundings obtained during SHEBA (October 1997-October 1998). It was found that the temperature gradient method produces a reliable estimate of ABL height. Additionally, the authors determined optimal threshold values of temperature gradient for stable boundary layer (SBL) and convective boundary layer (CBL) to be 6.5 K/100 m and 1.0 K/100 m, respectively. The maximum ABL height during the year was 1150 m occurred in May. Median values of Arctic ABL height in May, June, July, and August were 400 m, 430 m, 180 m, and 320 m, respectively. Arctic ABL heights are clearly higher in the spring than in the summer.展开更多
A high microwave performance enhancement-mode(E-mode)In_(0.4)Ga_(0.6)As channel metal-oxide-semiconductor field-effect transistor(MOSFET)with a Si-doped In_(0.49)Ga0.51P interfacial layer is fabricated.A 0.8-μm-gate-...A high microwave performance enhancement-mode(E-mode)In_(0.4)Ga_(0.6)As channel metal-oxide-semiconductor field-effect transistor(MOSFET)with a Si-doped In_(0.49)Ga0.51P interfacial layer is fabricated.A 0.8-μm-gate-length In_(0.4)Ga_(0.6)As MOSFET with a 5-nm Al_(2)O_(3) dielectric layer provides a current gain cutoff frequency of 16.7 GHz and a maximum oscillation frequency of 52 GHz.A semi-empirical small-signal-parameter extraction technique accounting for the low frequency anomaly of this MOSFET device is described,which is based on on-wafer S-parameter measurements.Excellent agreement between measured and simulated scattering parameters as well as the physically realistic circuit elements demonstrates the validity of this approach.展开更多
Inverse lithography technology(ILT)is intended to achieve optimal mask design to print a lithography target for a given lithography process.Full chip implementation of rigorous inverse lithography remains a challengin...Inverse lithography technology(ILT)is intended to achieve optimal mask design to print a lithography target for a given lithography process.Full chip implementation of rigorous inverse lithography remains a challenging task because of enormous computational resource requirements and long computational time.To achieve full chip ILT solution,attempts have been made by using machine learning techniques based on deep convolution neural network(DCNN).The reported input for such DCNN is the rasterized images of the lithography target;such pure geometrical input requires DCNN to possess considerable number of layers to learn the optical properties of the mask,the nonlinear imaging process,and the rigorous ILT algorithm as well.To alleviate the difficulties,we have proposed the physics based optimal feature vector design for machine learning ILT in our early report.Although physics based feature vector followed by feedforward neural network can provide the solution to machine learning ILT,the feature vector is long and it can consume considerable amount of memory resource in practical implementation.To improve the resource efficiency,we proposed a hybrid approach in this study by combining first few physics based feature maps with a specially designed DCNN structure to learn the rigorous ILT algorithm.Our results show that this approach can make machine learning ILT easy,fast and more accurate.展开更多
Cavity magnomechanics,exhibiting remarkable experimental tunability,rich magnonic nonlinearities,and compatibility with various quantum systems,has witnessed considerable advances in recent years.However,the potential...Cavity magnomechanics,exhibiting remarkable experimental tunability,rich magnonic nonlinearities,and compatibility with various quantum systems,has witnessed considerable advances in recent years.However,the potential benefits of using cavity magnomechanical(CMM)systems in further improving the performance of quantum-enhanced sensing for weak forces remain largely unexplored.Here we show that,by squeezing the magnons,the performance of a quantum CMM sensor can be significantly enhanced beyond the standard quantum limit(SQL).We find that,for comparable parameters,two orders of magnitude enhancement in the force sensitivity can be achieved in comparison with the case without magnon squeezing.Moreover,we obtain the optimal parameter regimes of homodyne angle for minimizing the added quantum noise.Our findings provide a promising approach for highly tunable and compatible quantum force sensing using hybrid CMM devices,with potential applications ranging from quantum precision measurements to quantum information processing.展开更多
A robust optimal framework is designed herein to mitigate the oscillatory dynamics in a doubly fed induction generator(DFIG)even in the presence of network disturbances and input variation.To address uncertain dynamic...A robust optimal framework is designed herein to mitigate the oscillatory dynamics in a doubly fed induction generator(DFIG)even in the presence of network disturbances and input variation.To address uncertain dynamics,herein,a novel transformation formula is developed for a wind energy conversion system.An unscented Kalman filter is applied to estimate the un-measured internal states of the wind energy conversion system using terminal measurements.The detailed convergence and stability analyses of the presented framework are investigated to validate its effectiveness.Additionally,comparative modal analyses are carried out to demonstrate the improvement in the damping of critical low-frequency oscillatory modes using the presented framework.The simulation results demonstrate satisfactory performance under various operating scenarios,such as increasing and decreasing wind speed and varying the terminal voltage.The comparative performance is demonstrated to validate the effectiveness of the presented framework over that of the state-of-the-art frameworks.Index Terms—Optimal control,power system,renew-able energy sources,wind energy conversion system,doubly fed induction generator.展开更多
Background To explore the clinical,radiological,and surgical characteristics of anterior perforated substance(APS)gliomas.Methods Twenty patients with APS glioma who were treated with surgery between March 2019 and Ja...Background To explore the clinical,radiological,and surgical characteristics of anterior perforated substance(APS)gliomas.Methods Twenty patients with APS glioma who were treated with surgery between March 2019 and January 2022 from Tiantan hospital were retrospectively reviewed.The clinical,histological and radiological data were collected.Results Twenty patients,including 7 males(55%)and 13 females(45%),with a mean age at diagnosis of 37.9 years(range,28-53 years)underwent operative intervention for APS.Headaches and dizziness were the most common preoperative symptoms in the majority patients(14,70%).Based on radiological features of MRI,the APS was classified into two subtypes,type A and type B.Seven patients(40%)in type A indicated a clear tumor margin,while 13 patients(60%)in type B showed an ill-defined margin.The surgical approach including frontal,temporal,and coronal frontal incisions for type A and type B tumors,respectively.Three patients in type A received total resection,while one patient in type B were total resected.Pathologically,12 cases(60%,12/20)were diagnosed as astrocytoma and 8 cases(20%,8/20)were oligodendroglioma.Meanwhile,17 cases(85%,17/20)had MGMT promotor methylation.Conclusion In this study,we performed the first systematic research of patients with APS glioma.Most of patients with APS presented headaches and dizziness symptoms.The APS glioma was further divided into two major radiological subtypes with relevant different surgical approaches.The APS glioma in type A were more likely to receive total resection.展开更多
Retinal neurodegeneration plays a significant role in the pathogenesis of diabetic retinopathy(DR),the leading cause of preventable blindness.In fact,the American Diabetes Association has defined DR as a highly specif...Retinal neurodegeneration plays a significant role in the pathogenesis of diabetic retinopathy(DR),the leading cause of preventable blindness.In fact,the American Diabetes Association has defined DR as a highly specific neurovascular complication(Solomon et al.,2017).Therefore,it is no longer acceptable to consider DR as merely a microvascular complication.In this regard,the term diabetic retinal disease(DRD)has been proposed as a broader term comprising microangiopathy and neurodegeneration.However,there are currently no treatments available that directly target the neurodegenerative changes of DR.This paper will give new insights into the translational research in this field with particular emphasis on glucagon-like peptide 1/dipeptidyl peptidase IV(GLP-1/DPP-IV)inhibitors.展开更多
Tibetan singing bowls emit low-frequency sounds and produce perceptible harmonic tones and vibrations through manual tapping.The sounds the singing bowls produce have been shown to enhance relaxation and reduce anxiet...Tibetan singing bowls emit low-frequency sounds and produce perceptible harmonic tones and vibrations through manual tapping.The sounds the singing bowls produce have been shown to enhance relaxation and reduce anxiety.However,the underlying mechanism remains unclear.In this study,we used chronic restraint stress or sleep deprivation to establish mouse models of anxiety that exhibit anxiety-like behaviors.We then supplied treatment with singing bowls in a bottomless cage placed on the top of a cushion.We found that unlike in humans,the combination of harmonic tones and vibrations did not improve anxietylike behaviors in mice,while individual vibration components did.Additionally,the vibration of singing bowls increased the level of N-methyl-D-aspartate receptor 1 in the somatosensory cortex and prefrontal cortex of the mice,decreased the level ofγ-aminobutyric acid A(GABA)receptorα1 subtype,reduced the level of CaMKII in the prefrontal cortex,and increased the number of GABAergic interneurons.At the same time,electrophysiological tests showed that the vibration of singing bowls significantly reduced the abnormal low-frequency gamma oscillation peak frequency in the medial prefrontal cortex caused by stress restraint pressure and sleep deprivation.Results from this study indicate that the vibration of singing bowls can alleviate anxiety-like behaviors by reducing abnormal molecular and electrophysiological events in somatosensory and medial prefrontal cortex.展开更多
Molecular dynamics simulations are carried out for describing growth of Pd and PdO nanoclusters using the ReaxFF force field. The resulting nanocluster structures are successfully compared to those of nanoclusters exp...Molecular dynamics simulations are carried out for describing growth of Pd and PdO nanoclusters using the ReaxFF force field. The resulting nanocluster structures are successfully compared to those of nanoclusters experimentally grown in a gas aggregation source. The PdO structure is quasi-crystalline as revealed by high resolution transmission microscope analysis for experimental PdO nanoclusters. The role of the nanocluster temperature in the molecular dynamics simulated growth is highlighted.展开更多
AIM: To investigate the effectiveness of combinationtherapy with transzonular triamcinolone-moxifloxacin andconventional perioperative drops in reducing postoperativecomplications of cataract surgery. METHODS: Electro...AIM: To investigate the effectiveness of combinationtherapy with transzonular triamcinolone-moxifloxacin andconventional perioperative drops in reducing postoperativecomplications of cataract surgery. METHODS: Electronic medical records of cataractsurgery patients (single surgeon) were reviewed fromJanuary 2018 to September 2021. The rate of postoperativecomplications including prolonged and/or recurrentpostoperative inflammation, endophthalmitis, cystoid macularedema (CME), and intraocular pressure (IOP) was comparedbetween the patients receiving combinative therapy andpatients receiving drops only. RESULTS: Totally 596 patients and 1057 eyes(Combinative-Therapy group 493 and Drop-Only group 564)were included in this study. Using combination therapyreduced the relative risk of postoperative inflammationby 26.9% (16.6% Combinative-Therapy vs 22.7% Drop-Only, P=0.013). The incidence of endophthalmitis was 0in Combinative-Therapy group vs 0.5% in Drop-Only group(relative risk reduction 100%), although not statisticallysignificant (P=0.10). The incidence of severe IOP spikeswas not significantly different between Combinative-Therapy (2.4%) and Drop-Only (1.6%) groups (P=0.33).The relative risk of postoperative CME was 51.4% less inthree months follow up visit in Combinative-Therapy group,although not statistically significant (P=0.07). The visualoutcome 1-month postop. (best corrected visual acuity) wassignificantly better in Combinative-Therapy (logMAR 0.10)compared to Drop-Only (logMAR 0.14) groups (P=0.02) whilethe baseline visual acuity was not significantly different. CONCLUSION: The combinative approach oftranszonular triamcinolone-moxifloxacin plus perioperativeeyedrops is an effective method to minimize postoperativeinflammation, with better visual outcomes. It couldpotentially reduce the risk of postoperative endophthalmitisand CME (near-significant P-values;larger studies couldanalyze better considering low incidence).展开更多
When checking the ice shape calculation software,its accuracy is judged based on the proximity between the calculated ice shape and the typical test ice shape.Therefore,determining the typical test ice shape becomes t...When checking the ice shape calculation software,its accuracy is judged based on the proximity between the calculated ice shape and the typical test ice shape.Therefore,determining the typical test ice shape becomes the key task of the icing wind tunnel tests.In the icing wind tunnel test of the tail wing model of a large amphibious aircraft,in order to obtain accurate typical test ice shape,the Romer Absolute Scanner is used to obtain the 3D point cloud data of the ice shape on the tail wing model.Then,the batch-learning self-organizing map(BLSOM)neural network is used to obtain the 2D average ice shape along the model direction based on the 3D point cloud data of the ice shape,while its tolerance band is calculated using the probabilistic statistical method.The results show that the combination of 2D average ice shape and its tolerance band can represent the 3D characteristics of the test ice shape effectively,which can be used as the typical test ice shape for comparative analysis with the calculated ice shape.展开更多
We investigate the electronic structure of NbGeSb with non-symmorphic symmetry.We employ angle-resolved photoemission spectroscopy(ARPES)to observe and identify the bulk and surface states over the Brillouin zone.By u...We investigate the electronic structure of NbGeSb with non-symmorphic symmetry.We employ angle-resolved photoemission spectroscopy(ARPES)to observe and identify the bulk and surface states over the Brillouin zone.By utilizing high-energy photons,we identify the bulk Fermi surface and bulk nodal line along the direction X–R,while the Fermi surface of the surface state is observed by using low-energy photons.We observe the splitting of surface bands away from the high-symmetry point X.The density functional theory calculations on bulk and 1 to 5-layer slab models,as well as spin textures of NbGeSb,verify that the band splitting could be attributed to the Rashba-like spin–orbit coupling caused by space-inversion-symmetry breaking at the surface.These splitted surface bands cross with each other,forming two-dimensional Weyl-like crossings that are protected by mirror symmetry.Our findings provide insights into the two-dimensional topological and symmetry-protected band inversion of surface states.展开更多
Bio-silica issued from diatom, a microalgae, is attracted increasing attention in material science thanks to its peculiar nanoarchitecture and related properties with versatile applications. The present work is a deep...Bio-silica issued from diatom, a microalgae, is attracted increasing attention in material science thanks to its peculiar nanoarchitecture and related properties with versatile applications. The present work is a deep analysis on morphological and chemical properties of bio-silica issued from fossil origin (diatomaceous earth) and living one (algal paste). An optimization in purification protocol was performed to obtain multiparous bio-silica from its raw media with keeping its original shape entirely. Multiple characterization methods as scanning electronic microscopy (SEM), infrared spectroscopy, x-ray diffraction (DRX), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDX), nitrogen adsorption and inverse gas chromatography (IGC), were used to check the purification protocol efficiency as well as to gather accurate information on morphology and chemical composition of diatom material obtained in large amount.展开更多
To gain further understanding of the luminescence properties of multiquantum wells and the factors affecting them on a microscopic level,cathodoluminescence combined with scanning transmission electron microscopy and ...To gain further understanding of the luminescence properties of multiquantum wells and the factors affecting them on a microscopic level,cathodoluminescence combined with scanning transmission electron microscopy and spectroscopy was used to measure the luminescence of In_(0.15)Ga_(0.85)N five-period multiquantum wells.The lattice-composition-energy relationship was established with the help of energy-dispersive x-ray spectroscopy,and the bandgaps of In_(0.15)Ga_(0.85)N and GaN in multiple quantum wells were extracted by electron energy loss spectroscopy to understand the features of cathodoluminescence spectra.The luminescence differences between different periods of multiquantum wells and the effects of defects such as composition fluctuation and dislocations on the luminescence of multiple quantum wells were revealed.Our study establishing the direct relationship between the atomic structure of In_(x)Ga_(1-x)N multiquantum wells and photoelectric properties provides useful information for nitride applications.展开更多
文摘ICSED (Improved Cluster Shade Edge Detection) algorithm and other various methods to accurately and efficiently detect edges on satellite data are presented. Error rate criterion is used to statistically evaluate the performances of these methods in detecting oceanic features for both noise free and noise contaminated AVHRR (Advanced Very High Resolution Radiometer) IR image with Kuroshio. Also, practical experiments in detecting the eddy of Kuroshio with these methods are carried out for comparison. Results show that the ICSED algorithm has more advantages than other methods in detecting mesoscale features of ocean. Finally, the effectiveness of window size of ICSED method to oceanic features detection is quantitatively discussed.
基金This research was supported by the National Natural Science Foundation of China(82041018,81770096,81700091,and 81800094)the National Science and Technology Major Project of the Ministry of Science and Technology of China(2019ZX09301001)+1 种基金the National Key Research and Development Program of the Ministry of Science and Technology of China(2020YFC0844300)the Fundamental Research Funds for the Central Universities(China)(2020kfyXGYJ011).
文摘It is difficult to identify suspected cases of atypical patients with coronavirus disease 2019(COVID-19),and data on severe or critical patients are scanty.This retrospective study presents the clinical,laboratory,and radiological profiles,treatments,and outcomes of atypical COVID-19 patients without respiratory symptoms or fever at onset.The study examined ten atypical patients out of 909 severe or critical patients diagnosed with COVID-19 in Wuhan Union Hospital West Campus between 25 January 2020 and 10 February 2020.Data were obtained from the electronic medical records of severe or critical patients without respiratory symptoms or fever at onset.Outcomes were followed up to discharge or death.Among 943 COVID-19 patients,909(96.4%)were severe or critical type.Of the severe or critical patients,ten(1.1%)presented without respiratory symptoms or fever at admission.The median age of the ten participants was 63 years(interquartile range(IQR):57–72),and seven participants were men.The median time from symptom onset to admission was 14 d(IQR:7–20).Eight of the ten patients had chronic diseases.The patients had fatigue(n=5),headache or dizziness(n=4),diarrhea(n=5),anorexia(n=3),nausea or vomiting(n=3),and eye discomfort(n=1).Four patients were found to have lymphopenia.Imaging examination revealed that nine patients had bilateral pneumonia and one had unilateral pneumonia.Eventually,two patients died and eight were discharged.In the discharged patients,the median time from admission to discharge lasted 24 d(IQR:13–43).In summary,some severe or critical COVID-19 patients were found to have no respiratory symptoms or fever at onset.All such atypical cases should be identified and quarantined as early as possible,since they tend to have a prolonged hospital stay or fatal outcomes.Chest computed tomography(CT)scan and nucleic acid detection should be performed immediately on close contacts of COVID-19 patients to screen out those with atypical infections,even if the contacts present without respiratory symptoms or fever at onset.
基金supported by the China Meteorological Administration under Grant GYHY201006024the Chinese Academy of Sciences Strategic Priority Research Program under Grant XDA05110104spon-sorship of National Science Foundation
文摘Utilizing aircraft sounding data collected from the Surface Heat Budget of the Arctic Ocean (SHEBA, 1998) campaign, the authors evaluated commonly-used profile methods for Arctic ABL height estimation by validating against the'true'ABL height from aircraft sounding profiles, where ABL height is defined as the top of the layer with significant turbulence. Furthermore, the best performing method was used to estimate ABL height from the one-year GPS soundings obtained during SHEBA (October 1997-October 1998). It was found that the temperature gradient method produces a reliable estimate of ABL height. Additionally, the authors determined optimal threshold values of temperature gradient for stable boundary layer (SBL) and convective boundary layer (CBL) to be 6.5 K/100 m and 1.0 K/100 m, respectively. The maximum ABL height during the year was 1150 m occurred in May. Median values of Arctic ABL height in May, June, July, and August were 400 m, 430 m, 180 m, and 320 m, respectively. Arctic ABL heights are clearly higher in the spring than in the summer.
基金Supported by the National Basic Research Program of China under Grant Nos 2011CBA00605 and 2010CB327501the National Science&Technology Major Project under Grant No 2011ZX02708-003One Hundred Talents Program of Chinese Academy of Sciences,and the Scientific Research Foundation for the Returned Overseas Chinese Scholars,the Ministry of Education of China.
文摘A high microwave performance enhancement-mode(E-mode)In_(0.4)Ga_(0.6)As channel metal-oxide-semiconductor field-effect transistor(MOSFET)with a Si-doped In_(0.49)Ga0.51P interfacial layer is fabricated.A 0.8-μm-gate-length In_(0.4)Ga_(0.6)As MOSFET with a 5-nm Al_(2)O_(3) dielectric layer provides a current gain cutoff frequency of 16.7 GHz and a maximum oscillation frequency of 52 GHz.A semi-empirical small-signal-parameter extraction technique accounting for the low frequency anomaly of this MOSFET device is described,which is based on on-wafer S-parameter measurements.Excellent agreement between measured and simulated scattering parameters as well as the physically realistic circuit elements demonstrates the validity of this approach.
文摘Inverse lithography technology(ILT)is intended to achieve optimal mask design to print a lithography target for a given lithography process.Full chip implementation of rigorous inverse lithography remains a challenging task because of enormous computational resource requirements and long computational time.To achieve full chip ILT solution,attempts have been made by using machine learning techniques based on deep convolution neural network(DCNN).The reported input for such DCNN is the rasterized images of the lithography target;such pure geometrical input requires DCNN to possess considerable number of layers to learn the optical properties of the mask,the nonlinear imaging process,and the rigorous ILT algorithm as well.To alleviate the difficulties,we have proposed the physics based optimal feature vector design for machine learning ILT in our early report.Although physics based feature vector followed by feedforward neural network can provide the solution to machine learning ILT,the feature vector is long and it can consume considerable amount of memory resource in practical implementation.To improve the resource efficiency,we proposed a hybrid approach in this study by combining first few physics based feature maps with a specially designed DCNN structure to learn the rigorous ILT algorithm.Our results show that this approach can make machine learning ILT easy,fast and more accurate.
基金supported by the National Natural Science Foundation of China(Grant No.11935006)supported by the National Natural Science Foundation of China(Grant No.12205054)+7 种基金the Science and Technology Innovation Program of Hunan Province(Grant No.2020RC4047)National Key R&D Program of China(Grant No.2024YFE0102400)Hunan Provincial Major Scitech Program(Grant No.2023ZJ1010)Ph.D.Research Foundation(BSJJ202122)supported by the Japan Society for the Promotion of Science(JSPS)Postdoctoral Fellowships for Research in Japan(No.P22018)Nippon Telegraph and Telephone Corporation(NTT)Research,the Japan Science and Technology Agency(JST)(via the Quantum Leap Flagship Program(Q-LEAP),and the Moonshot R&D(Grant No.JPMJMS2061))the Asian Office of Aerospace Research and Development(AOARD)(Grant No.FA2386-20-1-4069)the Office of Naval Research(ONR)Global(Grant No.N62909-23-1-2074)。
文摘Cavity magnomechanics,exhibiting remarkable experimental tunability,rich magnonic nonlinearities,and compatibility with various quantum systems,has witnessed considerable advances in recent years.However,the potential benefits of using cavity magnomechanical(CMM)systems in further improving the performance of quantum-enhanced sensing for weak forces remain largely unexplored.Here we show that,by squeezing the magnons,the performance of a quantum CMM sensor can be significantly enhanced beyond the standard quantum limit(SQL).We find that,for comparable parameters,two orders of magnitude enhancement in the force sensitivity can be achieved in comparison with the case without magnon squeezing.Moreover,we obtain the optimal parameter regimes of homodyne angle for minimizing the added quantum noise.Our findings provide a promising approach for highly tunable and compatible quantum force sensing using hybrid CMM devices,with potential applications ranging from quantum precision measurements to quantum information processing.
基金supported in part by the National Natural Science Foundation of China(No.62103296)the UK Engineering and Physical Sciences Research Council(No.EP/T021713/1)the Shanxi Scholarship Council of China(No.2023-062).
文摘A robust optimal framework is designed herein to mitigate the oscillatory dynamics in a doubly fed induction generator(DFIG)even in the presence of network disturbances and input variation.To address uncertain dynamics,herein,a novel transformation formula is developed for a wind energy conversion system.An unscented Kalman filter is applied to estimate the un-measured internal states of the wind energy conversion system using terminal measurements.The detailed convergence and stability analyses of the presented framework are investigated to validate its effectiveness.Additionally,comparative modal analyses are carried out to demonstrate the improvement in the damping of critical low-frequency oscillatory modes using the presented framework.The simulation results demonstrate satisfactory performance under various operating scenarios,such as increasing and decreasing wind speed and varying the terminal voltage.The comparative performance is demonstrated to validate the effectiveness of the presented framework over that of the state-of-the-art frameworks.Index Terms—Optimal control,power system,renew-able energy sources,wind energy conversion system,doubly fed induction generator.
基金funding by the National Natural Science Foundation of China(No.81772005,No.82102764)the collaborative innovative major special project supported by Beijing Municipal Science&Technology Commission(No.Z191100006619088)
文摘Background To explore the clinical,radiological,and surgical characteristics of anterior perforated substance(APS)gliomas.Methods Twenty patients with APS glioma who were treated with surgery between March 2019 and January 2022 from Tiantan hospital were retrospectively reviewed.The clinical,histological and radiological data were collected.Results Twenty patients,including 7 males(55%)and 13 females(45%),with a mean age at diagnosis of 37.9 years(range,28-53 years)underwent operative intervention for APS.Headaches and dizziness were the most common preoperative symptoms in the majority patients(14,70%).Based on radiological features of MRI,the APS was classified into two subtypes,type A and type B.Seven patients(40%)in type A indicated a clear tumor margin,while 13 patients(60%)in type B showed an ill-defined margin.The surgical approach including frontal,temporal,and coronal frontal incisions for type A and type B tumors,respectively.Three patients in type A received total resection,while one patient in type B were total resected.Pathologically,12 cases(60%,12/20)were diagnosed as astrocytoma and 8 cases(20%,8/20)were oligodendroglioma.Meanwhile,17 cases(85%,17/20)had MGMT promotor methylation.Conclusion In this study,we performed the first systematic research of patients with APS glioma.Most of patients with APS presented headaches and dizziness symptoms.The APS glioma was further divided into two major radiological subtypes with relevant different surgical approaches.The APS glioma in type A were more likely to receive total resection.
基金funded by grants from the Instituto de Salud CarlosⅢ(DTS18/0163 and ICI20/00129)co-funded by European Union。
文摘Retinal neurodegeneration plays a significant role in the pathogenesis of diabetic retinopathy(DR),the leading cause of preventable blindness.In fact,the American Diabetes Association has defined DR as a highly specific neurovascular complication(Solomon et al.,2017).Therefore,it is no longer acceptable to consider DR as merely a microvascular complication.In this regard,the term diabetic retinal disease(DRD)has been proposed as a broader term comprising microangiopathy and neurodegeneration.However,there are currently no treatments available that directly target the neurodegenerative changes of DR.This paper will give new insights into the translational research in this field with particular emphasis on glucagon-like peptide 1/dipeptidyl peptidase IV(GLP-1/DPP-IV)inhibitors.
基金supported by the National Natural Science Foundation of ChinaNos.32170950(to LY),31970915(to LY),31871170(to CL)+4 种基金the Natural Science Foundation of Guangdong Province for Major Cultivation ProjectNo.2018B030336001(to LY)the Natural Science Foundation of Guangdong Province,Nos.2021A1515010804(to CL),2023A1515010899(to CL)the Guangdong Grant‘Key Technologies for Treatment of Brain Disorders’No.2018B030332001(to CL)。
文摘Tibetan singing bowls emit low-frequency sounds and produce perceptible harmonic tones and vibrations through manual tapping.The sounds the singing bowls produce have been shown to enhance relaxation and reduce anxiety.However,the underlying mechanism remains unclear.In this study,we used chronic restraint stress or sleep deprivation to establish mouse models of anxiety that exhibit anxiety-like behaviors.We then supplied treatment with singing bowls in a bottomless cage placed on the top of a cushion.We found that unlike in humans,the combination of harmonic tones and vibrations did not improve anxietylike behaviors in mice,while individual vibration components did.Additionally,the vibration of singing bowls increased the level of N-methyl-D-aspartate receptor 1 in the somatosensory cortex and prefrontal cortex of the mice,decreased the level ofγ-aminobutyric acid A(GABA)receptorα1 subtype,reduced the level of CaMKII in the prefrontal cortex,and increased the number of GABAergic interneurons.At the same time,electrophysiological tests showed that the vibration of singing bowls significantly reduced the abnormal low-frequency gamma oscillation peak frequency in the medial prefrontal cortex caused by stress restraint pressure and sleep deprivation.Results from this study indicate that the vibration of singing bowls can alleviate anxiety-like behaviors by reducing abnormal molecular and electrophysiological events in somatosensory and medial prefrontal cortex.
文摘Molecular dynamics simulations are carried out for describing growth of Pd and PdO nanoclusters using the ReaxFF force field. The resulting nanocluster structures are successfully compared to those of nanoclusters experimentally grown in a gas aggregation source. The PdO structure is quasi-crystalline as revealed by high resolution transmission microscope analysis for experimental PdO nanoclusters. The role of the nanocluster temperature in the molecular dynamics simulated growth is highlighted.
文摘AIM: To investigate the effectiveness of combinationtherapy with transzonular triamcinolone-moxifloxacin andconventional perioperative drops in reducing postoperativecomplications of cataract surgery. METHODS: Electronic medical records of cataractsurgery patients (single surgeon) were reviewed fromJanuary 2018 to September 2021. The rate of postoperativecomplications including prolonged and/or recurrentpostoperative inflammation, endophthalmitis, cystoid macularedema (CME), and intraocular pressure (IOP) was comparedbetween the patients receiving combinative therapy andpatients receiving drops only. RESULTS: Totally 596 patients and 1057 eyes(Combinative-Therapy group 493 and Drop-Only group 564)were included in this study. Using combination therapyreduced the relative risk of postoperative inflammationby 26.9% (16.6% Combinative-Therapy vs 22.7% Drop-Only, P=0.013). The incidence of endophthalmitis was 0in Combinative-Therapy group vs 0.5% in Drop-Only group(relative risk reduction 100%), although not statisticallysignificant (P=0.10). The incidence of severe IOP spikeswas not significantly different between Combinative-Therapy (2.4%) and Drop-Only (1.6%) groups (P=0.33).The relative risk of postoperative CME was 51.4% less inthree months follow up visit in Combinative-Therapy group,although not statistically significant (P=0.07). The visualoutcome 1-month postop. (best corrected visual acuity) wassignificantly better in Combinative-Therapy (logMAR 0.10)compared to Drop-Only (logMAR 0.14) groups (P=0.02) whilethe baseline visual acuity was not significantly different. CONCLUSION: The combinative approach oftranszonular triamcinolone-moxifloxacin plus perioperativeeyedrops is an effective method to minimize postoperativeinflammation, with better visual outcomes. It couldpotentially reduce the risk of postoperative endophthalmitisand CME (near-significant P-values;larger studies couldanalyze better considering low incidence).
基金supported by the AG600 project of AVIC General Huanan Aircraft Industry Co.,Ltd.
文摘When checking the ice shape calculation software,its accuracy is judged based on the proximity between the calculated ice shape and the typical test ice shape.Therefore,determining the typical test ice shape becomes the key task of the icing wind tunnel tests.In the icing wind tunnel test of the tail wing model of a large amphibious aircraft,in order to obtain accurate typical test ice shape,the Romer Absolute Scanner is used to obtain the 3D point cloud data of the ice shape on the tail wing model.Then,the batch-learning self-organizing map(BLSOM)neural network is used to obtain the 2D average ice shape along the model direction based on the 3D point cloud data of the ice shape,while its tolerance band is calculated using the probabilistic statistical method.The results show that the combination of 2D average ice shape and its tolerance band can represent the 3D characteristics of the test ice shape effectively,which can be used as the typical test ice shape for comparative analysis with the calculated ice shape.
基金Project supported by the National Key Research and Development Program of China(Grant No.2022YFA1403803)H.M.is supported by the Fundamental Research Funds for the Central Universities,and the Research Funds of Renmin University of China(Grant No.22XNH099)+7 种基金The results of DFT calculations described in this paper are supported by HPC Cluster of ITP-CAS.M.L.is supported by the National Natural Science Foundation of China(Grant No.12204536)the Fundamental Research Funds for the Central Universities,and the Research Funds of People’s Public Security University of China(PPSUC)(Grant No.2023JKF02ZK09)T.L.X.is supported by the National Key R&D Program of China(Grant No.2019YFA0308602)the National Natural Science Foundation of China(Grant Nos.12074425 and 11874422)Y.Y.W.is supported by the National Natural Science Foundation of China(Grant No.12104011)H.Y.L.is supported by the National Natural Science Foundation of China(Grant No.12074213)the Major Basic Program of Natural Science Foundation of Shandong Province(Grant No.ZR2021ZD01)the Project of Introduction and Cultivation for Young Innovative Talents in Colleges and Universities of Shandong Province.
文摘We investigate the electronic structure of NbGeSb with non-symmorphic symmetry.We employ angle-resolved photoemission spectroscopy(ARPES)to observe and identify the bulk and surface states over the Brillouin zone.By utilizing high-energy photons,we identify the bulk Fermi surface and bulk nodal line along the direction X–R,while the Fermi surface of the surface state is observed by using low-energy photons.We observe the splitting of surface bands away from the high-symmetry point X.The density functional theory calculations on bulk and 1 to 5-layer slab models,as well as spin textures of NbGeSb,verify that the band splitting could be attributed to the Rashba-like spin–orbit coupling caused by space-inversion-symmetry breaking at the surface.These splitted surface bands cross with each other,forming two-dimensional Weyl-like crossings that are protected by mirror symmetry.Our findings provide insights into the two-dimensional topological and symmetry-protected band inversion of surface states.
文摘Bio-silica issued from diatom, a microalgae, is attracted increasing attention in material science thanks to its peculiar nanoarchitecture and related properties with versatile applications. The present work is a deep analysis on morphological and chemical properties of bio-silica issued from fossil origin (diatomaceous earth) and living one (algal paste). An optimization in purification protocol was performed to obtain multiparous bio-silica from its raw media with keeping its original shape entirely. Multiple characterization methods as scanning electronic microscopy (SEM), infrared spectroscopy, x-ray diffraction (DRX), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDX), nitrogen adsorption and inverse gas chromatography (IGC), were used to check the purification protocol efficiency as well as to gather accurate information on morphology and chemical composition of diatom material obtained in large amount.
基金Project supported by the National Key R&D Program of China (Grant No. 2019YFA0708202)the National Natural Science Foundation of China (Grant Nos. 11974023, 52021006, 61974139, 12074369, and 12104017)+1 种基金the “2011 Program” from the Peking–Tsinghua–IOP Collaborative Innovation Center of Quantum Matterthe Youth Supporting Program of Institute of Semiconductors
文摘To gain further understanding of the luminescence properties of multiquantum wells and the factors affecting them on a microscopic level,cathodoluminescence combined with scanning transmission electron microscopy and spectroscopy was used to measure the luminescence of In_(0.15)Ga_(0.85)N five-period multiquantum wells.The lattice-composition-energy relationship was established with the help of energy-dispersive x-ray spectroscopy,and the bandgaps of In_(0.15)Ga_(0.85)N and GaN in multiple quantum wells were extracted by electron energy loss spectroscopy to understand the features of cathodoluminescence spectra.The luminescence differences between different periods of multiquantum wells and the effects of defects such as composition fluctuation and dislocations on the luminescence of multiple quantum wells were revealed.Our study establishing the direct relationship between the atomic structure of In_(x)Ga_(1-x)N multiquantum wells and photoelectric properties provides useful information for nitride applications.