There have been some reports on autocrine of leukemic cell lines, however, very few on leukemic negative autocrine up to date. It was demonstrated that some of leukemic cell lines could produce Tumor Necrosis Factor(T...There have been some reports on autocrine of leukemic cell lines, however, very few on leukemic negative autocrine up to date. It was demonstrated that some of leukemic cell lines could produce Tumor Necrosis Factor(TNF) and also its receptor. We have found an inhibitor from murine leukemia L7811 which could inhibit autologus leukemic cells. Later on leukemic cells from another 615 murine transplantable leukemia L615 was found to have similar autoinhibitor activit. Subsequently, it was confirmed that other展开更多
基金Project supported by the National Natural Science Foundation of China.
文摘There have been some reports on autocrine of leukemic cell lines, however, very few on leukemic negative autocrine up to date. It was demonstrated that some of leukemic cell lines could produce Tumor Necrosis Factor(TNF) and also its receptor. We have found an inhibitor from murine leukemia L7811 which could inhibit autologus leukemic cells. Later on leukemic cells from another 615 murine transplantable leukemia L615 was found to have similar autoinhibitor activit. Subsequently, it was confirmed that other
