Two new ICRF antennas operating in the ion cyclotron radio frequency(ICRF) range have been developed for EAST to overcome the low coupling problem of the original antennas.The original ICRF antennas were limited in th...Two new ICRF antennas operating in the ion cyclotron radio frequency(ICRF) range have been developed for EAST to overcome the low coupling problem of the original antennas.The original ICRF antennas were limited in their power capacity due to insufficient coupling.The new antenna design takes into account both wave coupling and absorption processes through comprehensive wave coupling and absorption codes,with the dominant parallel wave number k∥of 7.5 m-1at dipole phasing.Through the use of these new ICRF antennas,we are able to achieve 3.8 MW output power and 360 s operation,respectively.The initial experimental results demonstrate the reliability of the antenna design method.展开更多
In this paper,general principle of the Surface Acoustic Wave(SAW) sensor in wired and wireless con-figurations will be developed and a review of recent works concerning the field of high temperature applications will ...In this paper,general principle of the Surface Acoustic Wave(SAW) sensor in wired and wireless con-figurations will be developed and a review of recent works concerning the field of high temperature applications will be presented.The first part will be devoted to aspects of data transmission and processing.Both configurations of SAW de-vice,delay line and resonator,will be discussed as well as the remote interrogation techniques used to collect and to proc-ess signal.The second part will be devoted to the material aspects.Indeed,knowing that the conventional piezoelectric substrates such as quartz or lithium niobate cannot be used at high temperature,the choice of the material constituting the SAW device(substrate & electrodes) is one of the challenges to face.We will focus our discussion on the Langasite,the current reference for high temperature applications,and on the AlN/Sapphire structure,the very promising alternative for application where the use of high frequency is required.展开更多
In this work, a fast(0.5 h), green microwave-assisted synthesis of single crystalline Sb_2Se_3 nanowires was developed. For the first time we demonstrated a facile solvent-mediated process, whereby intriguing nanostru...In this work, a fast(0.5 h), green microwave-assisted synthesis of single crystalline Sb_2Se_3 nanowires was developed. For the first time we demonstrated a facile solvent-mediated process, whereby intriguing nanostructures including antimony selenide(Sb_2Se_3) nanowires and selenium(Se) microrods can be achieved by merely varying the volume ratio of ethylene glycol(EG) and H_2O free from expensive chemical and additional surfactant. The achieved uniform Sb_2Se_3 nanowire is single crystalline along [001]growth direction with a diameter of 100 nm and a length up to tens of micrometers. When evaluated as an anode of lithium-ion battery, Sb_2Se_3 nanowire can deliver a high reversible capacity of 650.2 m Ah g^(-1) at 100 mA g^(-1) and a capacity retention of 63.8% after long-term 1000 cycles at 1000 mA g^(-1), as well as superior rate capability(389.5 m Ah g^(-1) at 2000 mA g^(-1)). This easy solvent-mediated microwave synthesis approach exhibits its great universe and importance towards the fabrication of high-performance metal chalcogenide electrode materials for future low-cost, large-scale energy storage systems.展开更多
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common causeof chronic liver disorder worldwide. It represents a spectrum that includes acontinuum of different clinical entities ranging from simple st...Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common causeof chronic liver disorder worldwide. It represents a spectrum that includes acontinuum of different clinical entities ranging from simple steatosis to nonalcoholicsteatohepatitis, which can evolve to cirrhosis and in some cases tohepatocellular carcinoma, ultimately leading to liver failure. The pathogenesis ofNAFLD and the mechanisms underlying its progression to more pathologicalstages are not completely understood. Besides genetic factors, evidence indicatesthat epigenetic mechanisms occurring in response to environmental stimuli alsocontribute to the disease risk. Noncoding RNAs (ncRNAs), including microRNAs,long noncoding RNAs, and circular RNAs, are one of the epigenetic factors thatplay key regulatory roles in the development of NAFLD. As the field of ncRNAsis rapidly evolving, the present review aims to explore the current state ofknowledge on the roles of these RNA species in the pathogenesis of NAFLD,highlight relevant mechanisms by which some ncRNAs can modulate regulatorynetworks implicated in NAFLD, and discuss key challenges and future directionsfacing current research in the hopes of developing ncRNAs as next-generationnon-invasive diagnostics and therapies in NAFLD and subsequent progression tohepatocellular carcinoma.展开更多
Surface acoustic wave(SAW)resonator used as wireless sensor was characterized and the parameters of its MBVD(Modified Butterworth-Van Dyke)model were extracted versus temperature.The extracted parameters lead toevalua...Surface acoustic wave(SAW)resonator used as wireless sensor was characterized and the parameters of its MBVD(Modified Butterworth-Van Dyke)model were extracted versus temperature.The extracted parameters lead toevaluate the resonator performancesin terms of Temperature coefficient of frequency(TCF)and quality factor(Q).An antenna was then associated with the SAW resonator and the entire system has been characterized and modeled.The good agreement experiment-simulation allows to define the optimum operating conditions of the wireless sensor.展开更多
In this work,Doppler reflectometry(DR)and radial correlation DR(RCDR)nonlinear scattering effects are studied using full-wave modeling with a set of representative FT-2 tokamak turbulence as inputs.Narrowing of the RC...In this work,Doppler reflectometry(DR)and radial correlation DR(RCDR)nonlinear scattering effects are studied using full-wave modeling with a set of representative FT-2 tokamak turbulence as inputs.Narrowing of the RCDR correlation function and widening of the DR poloidal wavenumber spectrum are demonstrated.An effect on the dependence of the DR signal frequency shift on the probing wavenumber is found,namely,this dependence‘linearizing’in the nonlinear scattering regime.Nonlinear effects are shown to be weaker for O-mode probing than for X-mode probing,while a faster transition to nonlinear regime is demonstrated for RCDR compared to DR in both probing scenarios.展开更多
A measure for the efficiency of a thermoelectric material is the figure of merit defined by ZT = S2T/ρκ, where S, ρ and κ are the electronic transport coefficients, Seebeck coefficient, electrical resistivity and ...A measure for the efficiency of a thermoelectric material is the figure of merit defined by ZT = S2T/ρκ, where S, ρ and κ are the electronic transport coefficients, Seebeck coefficient, electrical resistivity and thermal conductiviy, respectively. T is the absolute temperature. Large values for ZT have been realized in nanostructured materials such as superlattices, quantum dots, nanocomposites, and nanowires. In order to achieve further progress, (1) a fundamental understanding of the carrier transport in nanocomposites is necessary, and (2) effective experimental methods for designing, producing and measuring new material compositions with nanocomposite-structures are to be applied. During the last decades, a series of formulas has been derived for calculation of the electronic transport coefficients in composites and disordered alloys. Along the way, some puzzling phenomenons have been solved as why there are simple metals with positive thermopower? and what is the reason for the phenomenon of the “Giant Hall effect”? and what is the reason for the fact that amorphous composites can exist at all? In the present review article, (1), formulas will be presented for calculation of σ = (1/ρ), κ, S, and R in composites. R, the Hall coefficient, provides additional informations about the type of the dominant electronic carriers and their densities. It will be shown that these formulas can also be applied successfully for calculation of S, ρ, κ and R in nanocomposites if certain conditions are taken into account. Regarding point (2) we shall show that the combinatorial development of materials can provide unfeasible results if applied noncritically.展开更多
In spintronic applications,there is a constant demand for lower power consumption,high densities,and fast writing speed of data storage.All-optical switching(AOS)is a technique that uses laser pulses to switch the mag...In spintronic applications,there is a constant demand for lower power consumption,high densities,and fast writing speed of data storage.All-optical switching(AOS)is a technique that uses laser pulses to switch the magnetic state of a recording medium without any external devices,offering unsurpassed recording rates and a simple structure.Despite extensive research on the mechanism of AOS,low energy consumption and fast magnetization reversing remain challenging engineering questions.In this paper,we propose a newly designed cavity-enhanced AOS in Gd Co alloy,which promotes optical absorption by twofold,leading to a 50%reduction in energy consumption.Additionally,the time-resolved measurement shows that the time of reversing magnetization reduces at the same time.This new approach makes AOS an ideal solution for energy-effective and fast magnetic recording,paving the way for future developments in high-speed,low-power-consumption data recording devices.展开更多
The formation of long-range ordered aperiodic molecular films on quasicrystalline substrates is a new challenge that provides an opportunity for further surface functionalization. This aim can be realized through the ...The formation of long-range ordered aperiodic molecular films on quasicrystalline substrates is a new challenge that provides an opportunity for further surface functionalization. This aim can be realized through the smart selection of molecular building blocks, based on symmetry-matching between the underlying quasicrystal and individual molecules. It was previously found that the geometric registry between the C60 molecules and the 5- and 10-fold surfaces was key to the growth of quasiperiodic organic layers. However, an attempt to form a quasiperiodic C60 network on i-Ag-In-Yb substrates was unsuccessful, resulting in disordered molecular films. Here we report the growth of 5-fold symmetric corannulene C20H10 molecules on the 5-fold surfaces of i-Ag-In-Yb quasicrystals. Low-energy electron diffraction (LEED) and scanning tunneling microscopy (STM) revealed long-range quasiperiodic order and 5-fold rotational symmetry in self-assembled corannulene films. Recurrent decagonal molecular rings were seen, resulting from the decoration of specific adsorption sites with local pentagonal symmetry by corannulenes, adsorbed with their bowl-openings pointing away from the surface. They were identified as (Ag, In)-containing rhombic triacontahedral (RTH) duster centers and pentagonal Yb motifs, which cannot be occupied simultaneously due to steric hindrance. It is proposed that symmetry-matching between the molecule and specific substrate sites drives this organization. Alteration of the molecular rim by the introduction of CH substituents appeared to increase molecule mobility on the potential energy surface and facilitate trapping at these specific sites. This finding suggests that rational selection of molecular moiety enables the templated self-assembly of molecules leading to an ordered aperiodic corannulene layer.展开更多
Piezoelectric materials that generate electrical signals in response to mechanical strain can be used in tissue engineering to stimulate cell proliferation. Poly (vinylidene fluoride-trifluoroethylene) (P(VDF-TrF...Piezoelectric materials that generate electrical signals in response to mechanical strain can be used in tissue engineering to stimulate cell proliferation. Poly (vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)), a piezoelectric polymer, is widely used in biomaterial applications. We hypothesized that incorporation of zinc oxide (ZnO) nanoparticles into the P(VDF-TrFE) matrix could promote adhesion, migration, and proliferation of cells, as well as blood vessel formation (angiogenesis). In this study, we fabricated and comprehensively characterized a novel electrospun P(VDF-TrFE)/ZnO nanocomposite tissue engineering scaffold. We analyzed the morphological features of the polymeric matrix by scanning electron microscopy, and utilized Fourier transform infrared spectroscopy, X-ray diffraction, and differential scanning calorimetry to examine changes in the crystalline phases of the copolymer due to addition of the nanoparticles. We detected no or minimal adverse effects of the biomaterials with regard to blood compatibility in vitro, biocompatibility, and cytotoxicity, indicating that P(VDF-TrFE)/ZnO nanocomposite scaffolds are suitable for tissue engineering applications. Interestingly, human mesenchymal stem cells (hMSCs) and human umbilical vein endothelial cells cultured on the nanocomposite scaffolds exhibited higher cell viability, adhesion, and proliferation compared to cells cultured on tissue culture plates or neat P(VDF-TrFE) scaffolds. Nanocomposite scaffolds implanted into rats with or without hMSCs did not elicit immunological responses, as assessed by macroscopic analysis and histology. Importantly, nanocomposite scaffolds promoted angiogenesis, which was increased in scaffolds pre-seeded with hMSCs. Overall, our results highlight the potential of these novel P(VDF-TrFE)/ZnO nanocomposites for use in tissue engineering, due to their biocompatibility and ability to promote cell adhesion and angiogenesis.展开更多
In this paper,vanadium nitride(VN)thin films have been deposited on Al substrates by reactive magnetron sputtering.Thermochromic VO_(2) films have been obtained by air oxidation of VN samples performed at three temper...In this paper,vanadium nitride(VN)thin films have been deposited on Al substrates by reactive magnetron sputtering.Thermochromic VO_(2) films have been obtained by air oxidation of VN samples performed at three temperatures(450,525 and 550℃)at various durations(lower than 50 min).X-ray diffraction and Raman spectrometry of the VN oxidized films indicate that VO_(2) and V2O5 are the only phases produced during the oxidation process.Vanadium dioxide is the first oxide formed.It coexists with VN in a long period at 450℃ or suddenly disappears at 525 and 550℃.Whatever the temperature,V2O5 is exclusively detected after the total oxidation of VN.This oxide is detrimental to the thermochromic performance of films.The emissivity-switching properties of the oxidized films were analyzed by infrared camera in the 7.5e13 mm range.The comparison among all the samples exhibiting a thermochromic behavior shows that the maximum emissivity switch is independent of the oxidation temperature and the surface morphology of the samples.These results could open a new strategy in the investigation of VN oxidation as a method to obtain VO_(2),along with an insight into the correlation between surface morphology and optical properties.展开更多
基金supported by the National Key Research and Development Program of China (Nos. 2019YFE03070000and 2019YFE03070003)National Natural Science Foundation of China (Nos. 11975265 and 11775258)+2 种基金Comprehensive Research Facility for Fusion Technology Program of China (No. 2018-000052-73-01-001228)the Open Fund of Magnetic Confinement Fusion Laboratory of Anhui Province (No. 2021AMF01001)Hefei Science Center,CAS(No. 2021HSC-KPRD001)。
文摘Two new ICRF antennas operating in the ion cyclotron radio frequency(ICRF) range have been developed for EAST to overcome the low coupling problem of the original antennas.The original ICRF antennas were limited in their power capacity due to insufficient coupling.The new antenna design takes into account both wave coupling and absorption processes through comprehensive wave coupling and absorption codes,with the dominant parallel wave number k∥of 7.5 m-1at dipole phasing.Through the use of these new ICRF antennas,we are able to achieve 3.8 MW output power and 360 s operation,respectively.The initial experimental results demonstrate the reliability of the antenna design method.
基金supported by the REGION LORRAINE,Contrat Projet Etat Région 2007~2013Ple de Recherche Scientifique et Technologique.Matériaux,Energie,Procédés,Produits:Matériaux fonctionnels micro-et nanostructurés pour la réalisation de micro-et nanosystèmes."
文摘In this paper,general principle of the Surface Acoustic Wave(SAW) sensor in wired and wireless con-figurations will be developed and a review of recent works concerning the field of high temperature applications will be presented.The first part will be devoted to aspects of data transmission and processing.Both configurations of SAW de-vice,delay line and resonator,will be discussed as well as the remote interrogation techniques used to collect and to proc-ess signal.The second part will be devoted to the material aspects.Indeed,knowing that the conventional piezoelectric substrates such as quartz or lithium niobate cannot be used at high temperature,the choice of the material constituting the SAW device(substrate & electrodes) is one of the challenges to face.We will focus our discussion on the Langasite,the current reference for high temperature applications,and on the AlN/Sapphire structure,the very promising alternative for application where the use of high frequency is required.
基金supported by the National Key Research and Development Program of China(2016YFA0202603)the National Basic Research Program of China(2013CB934103)+5 种基金the National Natural Science Foundation of China(51521001,51602239)the National Natural Science Fund for Distinguished Young Scholars(51425204)Yellow Crane Talent(Science&Technology)Program of Wuhan Citythe Fundamental Research Funds for the Central Universities(WUT:2016III001,2016III003,2016IVA090)the Programme of Introducing Talents of Discipline to Universities(B17034)support from the Lorraine Region(nowpart of Grand Est Region)Cooperation Research Lorraine/Hubei Program 2015/2017
文摘In this work, a fast(0.5 h), green microwave-assisted synthesis of single crystalline Sb_2Se_3 nanowires was developed. For the first time we demonstrated a facile solvent-mediated process, whereby intriguing nanostructures including antimony selenide(Sb_2Se_3) nanowires and selenium(Se) microrods can be achieved by merely varying the volume ratio of ethylene glycol(EG) and H_2O free from expensive chemical and additional surfactant. The achieved uniform Sb_2Se_3 nanowire is single crystalline along [001]growth direction with a diameter of 100 nm and a length up to tens of micrometers. When evaluated as an anode of lithium-ion battery, Sb_2Se_3 nanowire can deliver a high reversible capacity of 650.2 m Ah g^(-1) at 100 mA g^(-1) and a capacity retention of 63.8% after long-term 1000 cycles at 1000 mA g^(-1), as well as superior rate capability(389.5 m Ah g^(-1) at 2000 mA g^(-1)). This easy solvent-mediated microwave synthesis approach exhibits its great universe and importance towards the fabrication of high-performance metal chalcogenide electrode materials for future low-cost, large-scale energy storage systems.
文摘Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common causeof chronic liver disorder worldwide. It represents a spectrum that includes acontinuum of different clinical entities ranging from simple steatosis to nonalcoholicsteatohepatitis, which can evolve to cirrhosis and in some cases tohepatocellular carcinoma, ultimately leading to liver failure. The pathogenesis ofNAFLD and the mechanisms underlying its progression to more pathologicalstages are not completely understood. Besides genetic factors, evidence indicatesthat epigenetic mechanisms occurring in response to environmental stimuli alsocontribute to the disease risk. Noncoding RNAs (ncRNAs), including microRNAs,long noncoding RNAs, and circular RNAs, are one of the epigenetic factors thatplay key regulatory roles in the development of NAFLD. As the field of ncRNAsis rapidly evolving, the present review aims to explore the current state ofknowledge on the roles of these RNA species in the pathogenesis of NAFLD,highlight relevant mechanisms by which some ncRNAs can modulate regulatorynetworks implicated in NAFLD, and discuss key challenges and future directionsfacing current research in the hopes of developing ncRNAs as next-generationnon-invasive diagnostics and therapies in NAFLD and subsequent progression tohepatocellular carcinoma.
基金supported in part by Oseo(now Bpi-France),Universite de Lorraine(Service Valorisation)and by the“Region Lorraine”via CPER project.
文摘Surface acoustic wave(SAW)resonator used as wireless sensor was characterized and the parameters of its MBVD(Modified Butterworth-Van Dyke)model were extracted versus temperature.The extracted parameters lead toevaluate the resonator performancesin terms of Temperature coefficient of frequency(TCF)and quality factor(Q).An antenna was then associated with the SAW resonator and the entire system has been characterized and modeled.The good agreement experiment-simulation allows to define the optimum operating conditions of the wireless sensor.
基金Modeling of the O-mode DR signals was performed with the financial support of RFBR grant 18-32-00031Modeling of the X-mode DR signals was performed with the financial support of the Russian Science Foundation grant 17-1201110+3 种基金Measurements at the FT-2 tokamak were supported by the state contract of the Ioffe Institutethe work are supported by grants 316088 and 318314 of the Academy of Finlandpartially carried out within the framework of the French Federation for Magnetic Fusion Studies(FR-FCM)the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 and 2019-2020 under grant agreement No.633053。
文摘In this work,Doppler reflectometry(DR)and radial correlation DR(RCDR)nonlinear scattering effects are studied using full-wave modeling with a set of representative FT-2 tokamak turbulence as inputs.Narrowing of the RCDR correlation function and widening of the DR poloidal wavenumber spectrum are demonstrated.An effect on the dependence of the DR signal frequency shift on the probing wavenumber is found,namely,this dependence‘linearizing’in the nonlinear scattering regime.Nonlinear effects are shown to be weaker for O-mode probing than for X-mode probing,while a faster transition to nonlinear regime is demonstrated for RCDR compared to DR in both probing scenarios.
文摘A measure for the efficiency of a thermoelectric material is the figure of merit defined by ZT = S2T/ρκ, where S, ρ and κ are the electronic transport coefficients, Seebeck coefficient, electrical resistivity and thermal conductiviy, respectively. T is the absolute temperature. Large values for ZT have been realized in nanostructured materials such as superlattices, quantum dots, nanocomposites, and nanowires. In order to achieve further progress, (1) a fundamental understanding of the carrier transport in nanocomposites is necessary, and (2) effective experimental methods for designing, producing and measuring new material compositions with nanocomposite-structures are to be applied. During the last decades, a series of formulas has been derived for calculation of the electronic transport coefficients in composites and disordered alloys. Along the way, some puzzling phenomenons have been solved as why there are simple metals with positive thermopower? and what is the reason for the phenomenon of the “Giant Hall effect”? and what is the reason for the fact that amorphous composites can exist at all? In the present review article, (1), formulas will be presented for calculation of σ = (1/ρ), κ, S, and R in composites. R, the Hall coefficient, provides additional informations about the type of the dominant electronic carriers and their densities. It will be shown that these formulas can also be applied successfully for calculation of S, ρ, κ and R in nanocomposites if certain conditions are taken into account. Regarding point (2) we shall show that the combinatorial development of materials can provide unfeasible results if applied noncritically.
基金Beihang Hefei Innovation Research Institute Project(BHKX-19-01)National Natural Science Foundation of China(12004025,52121001)。
文摘In spintronic applications,there is a constant demand for lower power consumption,high densities,and fast writing speed of data storage.All-optical switching(AOS)is a technique that uses laser pulses to switch the magnetic state of a recording medium without any external devices,offering unsurpassed recording rates and a simple structure.Despite extensive research on the mechanism of AOS,low energy consumption and fast magnetization reversing remain challenging engineering questions.In this paper,we propose a newly designed cavity-enhanced AOS in Gd Co alloy,which promotes optical absorption by twofold,leading to a 50%reduction in energy consumption.Additionally,the time-resolved measurement shows that the time of reversing magnetization reduces at the same time.This new approach makes AOS an ideal solution for energy-effective and fast magnetic recording,paving the way for future developments in high-speed,low-power-consumption data recording devices.
文摘The formation of long-range ordered aperiodic molecular films on quasicrystalline substrates is a new challenge that provides an opportunity for further surface functionalization. This aim can be realized through the smart selection of molecular building blocks, based on symmetry-matching between the underlying quasicrystal and individual molecules. It was previously found that the geometric registry between the C60 molecules and the 5- and 10-fold surfaces was key to the growth of quasiperiodic organic layers. However, an attempt to form a quasiperiodic C60 network on i-Ag-In-Yb substrates was unsuccessful, resulting in disordered molecular films. Here we report the growth of 5-fold symmetric corannulene C20H10 molecules on the 5-fold surfaces of i-Ag-In-Yb quasicrystals. Low-energy electron diffraction (LEED) and scanning tunneling microscopy (STM) revealed long-range quasiperiodic order and 5-fold rotational symmetry in self-assembled corannulene films. Recurrent decagonal molecular rings were seen, resulting from the decoration of specific adsorption sites with local pentagonal symmetry by corannulenes, adsorbed with their bowl-openings pointing away from the surface. They were identified as (Ag, In)-containing rhombic triacontahedral (RTH) duster centers and pentagonal Yb motifs, which cannot be occupied simultaneously due to steric hindrance. It is proposed that symmetry-matching between the molecule and specific substrate sites drives this organization. Alteration of the molecular rim by the introduction of CH substituents appeared to increase molecule mobility on the potential energy surface and facilitate trapping at these specific sites. This finding suggests that rational selection of molecular moiety enables the templated self-assembly of molecules leading to an ordered aperiodic corannulene layer.
文摘Piezoelectric materials that generate electrical signals in response to mechanical strain can be used in tissue engineering to stimulate cell proliferation. Poly (vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)), a piezoelectric polymer, is widely used in biomaterial applications. We hypothesized that incorporation of zinc oxide (ZnO) nanoparticles into the P(VDF-TrFE) matrix could promote adhesion, migration, and proliferation of cells, as well as blood vessel formation (angiogenesis). In this study, we fabricated and comprehensively characterized a novel electrospun P(VDF-TrFE)/ZnO nanocomposite tissue engineering scaffold. We analyzed the morphological features of the polymeric matrix by scanning electron microscopy, and utilized Fourier transform infrared spectroscopy, X-ray diffraction, and differential scanning calorimetry to examine changes in the crystalline phases of the copolymer due to addition of the nanoparticles. We detected no or minimal adverse effects of the biomaterials with regard to blood compatibility in vitro, biocompatibility, and cytotoxicity, indicating that P(VDF-TrFE)/ZnO nanocomposite scaffolds are suitable for tissue engineering applications. Interestingly, human mesenchymal stem cells (hMSCs) and human umbilical vein endothelial cells cultured on the nanocomposite scaffolds exhibited higher cell viability, adhesion, and proliferation compared to cells cultured on tissue culture plates or neat P(VDF-TrFE) scaffolds. Nanocomposite scaffolds implanted into rats with or without hMSCs did not elicit immunological responses, as assessed by macroscopic analysis and histology. Importantly, nanocomposite scaffolds promoted angiogenesis, which was increased in scaffolds pre-seeded with hMSCs. Overall, our results highlight the potential of these novel P(VDF-TrFE)/ZnO nanocomposites for use in tissue engineering, due to their biocompatibility and ability to promote cell adhesion and angiogenesis.
基金supported by the French PIA project“Lorraine Universite d’Excellence”,reference ANR-15-IDEX-04-LUE.
文摘In this paper,vanadium nitride(VN)thin films have been deposited on Al substrates by reactive magnetron sputtering.Thermochromic VO_(2) films have been obtained by air oxidation of VN samples performed at three temperatures(450,525 and 550℃)at various durations(lower than 50 min).X-ray diffraction and Raman spectrometry of the VN oxidized films indicate that VO_(2) and V2O5 are the only phases produced during the oxidation process.Vanadium dioxide is the first oxide formed.It coexists with VN in a long period at 450℃ or suddenly disappears at 525 and 550℃.Whatever the temperature,V2O5 is exclusively detected after the total oxidation of VN.This oxide is detrimental to the thermochromic performance of films.The emissivity-switching properties of the oxidized films were analyzed by infrared camera in the 7.5e13 mm range.The comparison among all the samples exhibiting a thermochromic behavior shows that the maximum emissivity switch is independent of the oxidation temperature and the surface morphology of the samples.These results could open a new strategy in the investigation of VN oxidation as a method to obtain VO_(2),along with an insight into the correlation between surface morphology and optical properties.