This study aims to determine the retention time of iodinated contrast agents (ICA) in the coronary artery. The mechanical aspect of ICA displacement was studied in order to better understand the effect of these produc...This study aims to determine the retention time of iodinated contrast agents (ICA) in the coronary artery. The mechanical aspect of ICA displacement was studied in order to better understand the effect of these products on the inner wall of the artery of patients with coronary artery stenosis, undergoing repeated imaging examinations with iodinated contrast agents. ICA flow, ICA and blood flow in the artery were modelled. The fluid was regarded to be viscous, incompressible and Newtonian. Blood flow was presumed to be unidirectional, laminar and unstationary. Iodine flow velocity and retention time were calculated using the Runge-Kutta 4th order method programmed in C++ and MatLab R2013a language. The results showed that for coronary artery CT-scans, ICA retention time is 1 minute 40 seconds and for coronary arteriography it is between 2.41 and 3.61 seconds. The values calculated were compared to theoretical values and to clinical observations. The results enabled us to validate our model.展开更多
Pre-compacted elements (disks, tutus) of bentonite/sand mixture are candidate materials for sealing plugs of radioactive waste disposal. Choice of this material is mainly based on its swelling capacity allowing all ...Pre-compacted elements (disks, tutus) of bentonite/sand mixture are candidate materials for sealing plugs of radioactive waste disposal. Choice of this material is mainly based on its swelling capacity allowing all gaps in the system to be sealed, and on its low permeability. When emplaced in the gallery, these elements will start to absorb water from the host rock and swell. Thereby, a swelling pressure will develop in the radial direction against the host rock and in the axial direction against the support structure. In this work, the swelling pressure of a small scale compacted disk of bentonite and sand was experimentally studied in both radial and axial directions. Different swelling kinetics were identified for different dry densities and along different directions. As a rule, the swelling pressure starts increasing quickly, reaches a peak value, decreases a little and finally stabilises. For some dry densities, higher peaks were observed in the radial direction than in the axial direction. The presence of peaks is related to the microstructure change and to the collapse of macro- pores. In parallel to the mechanical tests, microstructure investigation at the sample scale was conducted using microfocus X-ray computed tomography (BCT). Image observation showed a denser structure in the centre and a looser one in the border, which was also confirmed by image analysis. This structure heterogeneity in the radial direction and the occurrence of macro-pores close to the radial boundary of the sample can explain the large peaks observed in the radial swelling pressure evolution. Another interesting result is the higher anisotropy found at lower bentonite dry densities, which was also analysed by means ofμCT observation of a sample at low bentonite dry density after the end of test. It was found that the macro-pores, especially those between sand grains, were not filled by swelled bentonite, which preserved the anisotropic microstructure caused by uniaxial compression due to the absence of microstructure collapse.展开更多
Background:Forests are an important sink for atmospheric carbon and could release that carbon upon deforestation and degradation.Knowing stand biomass dynamic of evergreen forests has become necessary to improve curre...Background:Forests are an important sink for atmospheric carbon and could release that carbon upon deforestation and degradation.Knowing stand biomass dynamic of evergreen forests has become necessary to improve current biomass production models.The different growth processes of managed forests compared to self-managed forests imply an adaptation of biomass prediction models.Methods:In this paper we model through three models the biomass growth of two tree species(Japanese cedar,Japanese cypress)at stand level whether they are managed or not(self-thinning).One of them is named self-thinned model which uses a specific self-thinning parameterαand adapted to self-managed forests and an other model is named thinned model adapted to managed forests.The latter is compared to a Mitscherlich model.The self-thinned model takes into account the light competition between trees relying on easily observable parameters(e.g.stand density).A Bayesian inference was carried out to determine parameters values according to a large database collected.Results:In managed forest,Bayesian inference results showed obviously a lack of identifiability of Mitscherlich model parameters and a strong evidence for the thinned model in comparison to Mitscherlich model.In self-thinning forest,the results of Bayesian inference are in accordance with the self-thinning 3/2 rule(α=1.4).Structural dependence between stand density and stand yield in self-thinned model allows to qualifying the expression of biological time as a function of physical time and better qualify growth and mortality rate.Relative mortality rate is 2.5 times more important than relative growth rate after about 40 years old.Stand density and stand yield can be expressed as function of biological time,showing that yield is independent of initial density.Conclusions:This paper addressed stand biomass dynamic models of evergreen forests in order to improve biomass growth dynamic assessment at regional scale relying on easily observable parameters.These models can be used to dynamically estimate forest biomass and more generally estimate the carbon balance and could contribute to a better understanding of climate change factors.展开更多
During the course of a hypothetical severe accident in a nuclear Pressurized Water Reactor (PWR), containment reactor is pressurized by steam and hydrogen released from a primary circuit breach and distributed into ...During the course of a hypothetical severe accident in a nuclear Pressurized Water Reactor (PWR), containment reactor is pressurized by steam and hydrogen released from a primary circuit breach and distributed into the containment according to convective flows and steam wall condensation. In addition, core degradation leads to fission products released into the containment. Water spraying is used in the containment as mitigation means in order to reduce pressure, to remove fission products and to enhance the gas mixing in case of presence of hydrogen. This paper presents results of the TOSQAN aerosol program undertaken by the Institute de Radioprotection et de Sfiret6 Nucl6aire (IRSN) devoted to study the aerosol removal by a spray, for typical accidental thermal hydraulic conditions in PWR containment. The TOSQAN facility is a large enclosure devoted to simulate typical accidental thermal hydraulic flow conditions in nuclear PWR containment.展开更多
文摘This study aims to determine the retention time of iodinated contrast agents (ICA) in the coronary artery. The mechanical aspect of ICA displacement was studied in order to better understand the effect of these products on the inner wall of the artery of patients with coronary artery stenosis, undergoing repeated imaging examinations with iodinated contrast agents. ICA flow, ICA and blood flow in the artery were modelled. The fluid was regarded to be viscous, incompressible and Newtonian. Blood flow was presumed to be unidirectional, laminar and unstationary. Iodine flow velocity and retention time were calculated using the Runge-Kutta 4th order method programmed in C++ and MatLab R2013a language. The results showed that for coronary artery CT-scans, ICA retention time is 1 minute 40 seconds and for coronary arteriography it is between 2.41 and 3.61 seconds. The values calculated were compared to theoretical values and to clinical observations. The results enabled us to validate our model.
文摘Pre-compacted elements (disks, tutus) of bentonite/sand mixture are candidate materials for sealing plugs of radioactive waste disposal. Choice of this material is mainly based on its swelling capacity allowing all gaps in the system to be sealed, and on its low permeability. When emplaced in the gallery, these elements will start to absorb water from the host rock and swell. Thereby, a swelling pressure will develop in the radial direction against the host rock and in the axial direction against the support structure. In this work, the swelling pressure of a small scale compacted disk of bentonite and sand was experimentally studied in both radial and axial directions. Different swelling kinetics were identified for different dry densities and along different directions. As a rule, the swelling pressure starts increasing quickly, reaches a peak value, decreases a little and finally stabilises. For some dry densities, higher peaks were observed in the radial direction than in the axial direction. The presence of peaks is related to the microstructure change and to the collapse of macro- pores. In parallel to the mechanical tests, microstructure investigation at the sample scale was conducted using microfocus X-ray computed tomography (BCT). Image observation showed a denser structure in the centre and a looser one in the border, which was also confirmed by image analysis. This structure heterogeneity in the radial direction and the occurrence of macro-pores close to the radial boundary of the sample can explain the large peaks observed in the radial swelling pressure evolution. Another interesting result is the higher anisotropy found at lower bentonite dry densities, which was also analysed by means ofμCT observation of a sample at low bentonite dry density after the end of test. It was found that the macro-pores, especially those between sand grains, were not filled by swelled bentonite, which preserved the anisotropic microstructure caused by uniaxial compression due to the absence of microstructure collapse.
基金the State financial support managed by the Agence Nationale de la Recherche,allocated in“investissements d’Avenir”framework programme under reference AMORAD,ANR-11-RNSR-0002.
文摘Background:Forests are an important sink for atmospheric carbon and could release that carbon upon deforestation and degradation.Knowing stand biomass dynamic of evergreen forests has become necessary to improve current biomass production models.The different growth processes of managed forests compared to self-managed forests imply an adaptation of biomass prediction models.Methods:In this paper we model through three models the biomass growth of two tree species(Japanese cedar,Japanese cypress)at stand level whether they are managed or not(self-thinning).One of them is named self-thinned model which uses a specific self-thinning parameterαand adapted to self-managed forests and an other model is named thinned model adapted to managed forests.The latter is compared to a Mitscherlich model.The self-thinned model takes into account the light competition between trees relying on easily observable parameters(e.g.stand density).A Bayesian inference was carried out to determine parameters values according to a large database collected.Results:In managed forest,Bayesian inference results showed obviously a lack of identifiability of Mitscherlich model parameters and a strong evidence for the thinned model in comparison to Mitscherlich model.In self-thinning forest,the results of Bayesian inference are in accordance with the self-thinning 3/2 rule(α=1.4).Structural dependence between stand density and stand yield in self-thinned model allows to qualifying the expression of biological time as a function of physical time and better qualify growth and mortality rate.Relative mortality rate is 2.5 times more important than relative growth rate after about 40 years old.Stand density and stand yield can be expressed as function of biological time,showing that yield is independent of initial density.Conclusions:This paper addressed stand biomass dynamic models of evergreen forests in order to improve biomass growth dynamic assessment at regional scale relying on easily observable parameters.These models can be used to dynamically estimate forest biomass and more generally estimate the carbon balance and could contribute to a better understanding of climate change factors.
文摘During the course of a hypothetical severe accident in a nuclear Pressurized Water Reactor (PWR), containment reactor is pressurized by steam and hydrogen released from a primary circuit breach and distributed into the containment according to convective flows and steam wall condensation. In addition, core degradation leads to fission products released into the containment. Water spraying is used in the containment as mitigation means in order to reduce pressure, to remove fission products and to enhance the gas mixing in case of presence of hydrogen. This paper presents results of the TOSQAN aerosol program undertaken by the Institute de Radioprotection et de Sfiret6 Nucl6aire (IRSN) devoted to study the aerosol removal by a spray, for typical accidental thermal hydraulic conditions in PWR containment. The TOSQAN facility is a large enclosure devoted to simulate typical accidental thermal hydraulic flow conditions in nuclear PWR containment.