有 H pylori 的感染是与胃的癌症联系的最重要的已知的病因学的因素。当有 H pylori 的胃粘膜的殖民导致活跃、长期的胃炎在时几乎，所有个人感染了，得胃的癌症的可能性取决于环境、细菌的毒力和主人 specific 因素。所有胃的癌症盒子...有 H pylori 的感染是与胃的癌症联系的最重要的已知的病因学的因素。当有 H pylori 的胃粘膜的殖民导致活跃、长期的胃炎在时几乎，所有个人感染了，得胃的癌症的可能性取决于环境、细菌的毒力和主人 specific 因素。所有胃的癌症盒子的多数对 H pylori 感染并且因此可归因理论上可防止。从在一个早时间点的 H pylori 的根除能阻止的动物模型有证据胃的癌症开发。然而，使随机化在人在胃的癌症的发生上探索 H pylori 根除的预防效果的临床的审判仍然保持稀少并且让步了冲突结果。为在为 H pylori 的风险的病人的鉴定的更好的标记导致了胃的恶意被需要允许更有效的公共根除策略的发展。同时，屏蔽并且在胃的癌症病人以及某些高风险的人口的一度的亲戚的 H pylori 的治疗可能是有益的。展开更多
AIM To report 3 of 120 patients on the German MALT lymphoma trial with H. pYlori-associated gastric MALT Iymphoma who developed early gastric cancer 4 and 5 years, after complete Iymphoma remission following cure of H...AIM To report 3 of 120 patients on the German MALT lymphoma trial with H. pYlori-associated gastric MALT Iymphoma who developed early gastric cancer 4 and 5 years, after complete Iymphoma remission following cure of H. pylori infection.PATIENTS AND RESULTS Three patients (two men, 74 and 70 years; one women, 77 years)with H. pylori -associated low-grade MALTlymphoma achieved complete lymphoma remission after being cured. Surveillance endoscopies were performed twice a year in accordance to the protocol. Four years aftercomplete lymphoma remission in two patients,and after 5 years in the other, early gastric adenocarcinoma of the mucosa-type, type Ⅱ a and type Ⅱ c, respectively, was detetcted,which were completely removed by endoscopic mucosa resection. in one patient, the gastric cancer was diagnosed at the same location as the previous. MALT lymphoma, in the other patients it was detected at different sites of the stomach distant from location of the previous MALT lymphoma. The patients were H. pylori negative during the whole follow-up time.CONCLUSION These findings strengthen the importance of regular long-term follow-up endoscopies in patients with complete remission of gastric MALT lymphoma after cure of H.pylori infection. Furthermore, gastric adenocarcinoma may develop despite eradication of H. pylori.展开更多
TO THE EDITOR
With great interest we read the recent retrospectice study by Barta et al (1) dealing with the clinical presentation of patients with microscopic colitis. They investigated in a cohort of 53 patients wit...TO THE EDITOR
With great interest we read the recent retrospectice study by Barta et al (1) dealing with the clinical presentation of patients with microscopic colitis. They investigated in a cohort of 53 patients with microscopic colitis (46 with collagenous colitis, 7 with lymphocytic colitis)the relationship between microscopic colitis and both constipation and diarrhea. One of their mean finding was that abdominal pain, diarrhea and constipation was a common symptom complex of patients with microscopic colitis, thus the face of microcopic colitis resembles the subgroups of irritable bowel syndrome (IBS).展开更多
文摘有 H pylori 的感染是与胃的癌症联系的最重要的已知的病因学的因素。当有 H pylori 的胃粘膜的殖民导致活跃、长期的胃炎在时几乎，所有个人感染了，得胃的癌症的可能性取决于环境、细菌的毒力和主人 specific 因素。所有胃的癌症盒子的多数对 H pylori 感染并且因此可归因理论上可防止。从在一个早时间点的 H pylori 的根除能阻止的动物模型有证据胃的癌症开发。然而，使随机化在人在胃的癌症的发生上探索 H pylori 根除的预防效果的临床的审判仍然保持稀少并且让步了冲突结果。为在为 H pylori 的风险的病人的鉴定的更好的标记导致了胃的恶意被需要允许更有效的公共根除策略的发展。同时，屏蔽并且在胃的癌症病人以及某些高风险的人口的一度的亲戚的 H pylori 的治疗可能是有益的。
文摘AIM To report 3 of 120 patients on the German MALT lymphoma trial with H. pYlori-associated gastric MALT Iymphoma who developed early gastric cancer 4 and 5 years, after complete Iymphoma remission following cure of H. pylori infection.PATIENTS AND RESULTS Three patients (two men, 74 and 70 years; one women, 77 years)with H. pylori -associated low-grade MALTlymphoma achieved complete lymphoma remission after being cured. Surveillance endoscopies were performed twice a year in accordance to the protocol. Four years aftercomplete lymphoma remission in two patients,and after 5 years in the other, early gastric adenocarcinoma of the mucosa-type, type Ⅱ a and type Ⅱ c, respectively, was detetcted,which were completely removed by endoscopic mucosa resection. in one patient, the gastric cancer was diagnosed at the same location as the previous. MALT lymphoma, in the other patients it was detected at different sites of the stomach distant from location of the previous MALT lymphoma. The patients were H. pylori negative during the whole follow-up time.CONCLUSION These findings strengthen the importance of regular long-term follow-up endoscopies in patients with complete remission of gastric MALT lymphoma after cure of H.pylori infection. Furthermore, gastric adenocarcinoma may develop despite eradication of H. pylori.
文摘TO THE EDITOR
With great interest we read the recent retrospectice study by Barta et al (1) dealing with the clinical presentation of patients with microscopic colitis. They investigated in a cohort of 53 patients with microscopic colitis (46 with collagenous colitis, 7 with lymphocytic colitis)the relationship between microscopic colitis and both constipation and diarrhea. One of their mean finding was that abdominal pain, diarrhea and constipation was a common symptom complex of patients with microscopic colitis, thus the face of microcopic colitis resembles the subgroups of irritable bowel syndrome (IBS).
