Hypothesis: Although mineral deficiency in particular magnesium is a known risk factor for cardiovascular disease intervention experiments with magnesium show only modest results. Previously published data suggest tha...Hypothesis: Although mineral deficiency in particular magnesium is a known risk factor for cardiovascular disease intervention experiments with magnesium show only modest results. Previously published data suggest that there may be particular risk groups in the population. The study was undertaken to investigate if such risk groups could be identified. Experimental design: Subjects (n = 31) were 50 - 79 years old with no disease. The 24 hour urinary excretion of urea (proxy for acidity), magnesium, calcium, and potassium was measured at two week intervals, with and without intervention with mineral water. Intervention with mineral water comprised 75 mL daily, supplying 3.1 mmol Mg, 2.3 Ca, and 0.02 K. Major results: There was a significant relation between acidity and excretion of magnesium, calcium, and potassium, both at one occasion and regarding changes over time. Among subjects with a high secretion of urea there was an inverse relation between the excretion of magnesium and systolic blood pressure. After intervention with mineral water, there was a strong tendency to a decrease in the systolic blood pressure among those with an initial high excretion of urea and a low excretion of magnesium. Conclusions: The results demonstrate the importance of acid-base conditions for mineral homeostasis and suggest the presence of risk groups in the population, related either to a low intake or to a disorder in the reabsorbtion mechanisms. Mineral water decreased the systolic blood pressure in that particular risk group.展开更多
Guaiazulene-containing ointments are routinely used for breast care during breastfeeding. It has also been proposed that nipple and areola area of non-breastfeeding women might benefit from use of this azulene. In a s...Guaiazulene-containing ointments are routinely used for breast care during breastfeeding. It has also been proposed that nipple and areola area of non-breastfeeding women might benefit from use of this azulene. In a study with 51 women, it was investigated whether the use of a guaiazulene-containing ointment (Garmastan?) would improve look, elasticity and sensitivity of nipple and areola area within 4 month daily application. About one third of study participants reported improvement in sensitivity, elasticity and look of the investigated area of the breast. Assessment of doctors revealed a clear improvement in elasticity and sensitivity of the nipple and areola area over study period. Nearly all women wished to continue the use of the ointment after end of the study. In conclusion, the use of Garmastan? ointment is able to improve sensitivity and elasticity of the nipple and areola area of the breasts of non-breastfeeding women.展开更多
文摘Hypothesis: Although mineral deficiency in particular magnesium is a known risk factor for cardiovascular disease intervention experiments with magnesium show only modest results. Previously published data suggest that there may be particular risk groups in the population. The study was undertaken to investigate if such risk groups could be identified. Experimental design: Subjects (n = 31) were 50 - 79 years old with no disease. The 24 hour urinary excretion of urea (proxy for acidity), magnesium, calcium, and potassium was measured at two week intervals, with and without intervention with mineral water. Intervention with mineral water comprised 75 mL daily, supplying 3.1 mmol Mg, 2.3 Ca, and 0.02 K. Major results: There was a significant relation between acidity and excretion of magnesium, calcium, and potassium, both at one occasion and regarding changes over time. Among subjects with a high secretion of urea there was an inverse relation between the excretion of magnesium and systolic blood pressure. After intervention with mineral water, there was a strong tendency to a decrease in the systolic blood pressure among those with an initial high excretion of urea and a low excretion of magnesium. Conclusions: The results demonstrate the importance of acid-base conditions for mineral homeostasis and suggest the presence of risk groups in the population, related either to a low intake or to a disorder in the reabsorbtion mechanisms. Mineral water decreased the systolic blood pressure in that particular risk group.
文摘Guaiazulene-containing ointments are routinely used for breast care during breastfeeding. It has also been proposed that nipple and areola area of non-breastfeeding women might benefit from use of this azulene. In a study with 51 women, it was investigated whether the use of a guaiazulene-containing ointment (Garmastan?) would improve look, elasticity and sensitivity of nipple and areola area within 4 month daily application. About one third of study participants reported improvement in sensitivity, elasticity and look of the investigated area of the breast. Assessment of doctors revealed a clear improvement in elasticity and sensitivity of the nipple and areola area over study period. Nearly all women wished to continue the use of the ointment after end of the study. In conclusion, the use of Garmastan? ointment is able to improve sensitivity and elasticity of the nipple and areola area of the breasts of non-breastfeeding women.
