Research discussing potential environmental toxins that may be related to the etiology of childhood leukemia has been growing. The suspected environmental contaminants include solvents, air pollutants, pesticides, and...Research discussing potential environmental toxins that may be related to the etiology of childhood leukemia has been growing. The suspected environmental contaminants include solvents, air pollutants, pesticides, and tobacco smoke. Exposure to various pesticides has come under particular scrutiny, with positive associations with childhood leukemia [1]. Poynter et al. [2] conducted a population-based study assessing the association between self-reported chemical exposures and odds of acute myeloid leukemia (AML) and myelodysplastic syndromes(MDS).展开更多
Genetic modification (GM) represents new opportunities for enhanced crop features such as improved insect resistance and herbicide tolerance. The technology allows for cross-species alterations, therefore potentially ...Genetic modification (GM) represents new opportunities for enhanced crop features such as improved insect resistance and herbicide tolerance. The technology allows for cross-species alterations, therefore potentially allowing a vast array of novel traits. Many GM crops have been developed and approved for human and animal consumption. The present study investigated a triple-stacked GM corn variety containing modifications for insect resistance (via cry1Ab and cry3Bb1 genes) and herbicide tolerance (via an EPSPS gene), which was fed to rats for six months. The study investigated the mucosa of the stomach. Alterations to tight junction apposition, gland dilatations with epithelial elongation and dysplasia in the GM-fed rats were observed. These results indicate that GM-corn may have an effect on rat stomach mucosa, which may have health implications.展开更多
文摘Research discussing potential environmental toxins that may be related to the etiology of childhood leukemia has been growing. The suspected environmental contaminants include solvents, air pollutants, pesticides, and tobacco smoke. Exposure to various pesticides has come under particular scrutiny, with positive associations with childhood leukemia [1]. Poynter et al. [2] conducted a population-based study assessing the association between self-reported chemical exposures and odds of acute myeloid leukemia (AML) and myelodysplastic syndromes(MDS).
文摘Genetic modification (GM) represents new opportunities for enhanced crop features such as improved insect resistance and herbicide tolerance. The technology allows for cross-species alterations, therefore potentially allowing a vast array of novel traits. Many GM crops have been developed and approved for human and animal consumption. The present study investigated a triple-stacked GM corn variety containing modifications for insect resistance (via cry1Ab and cry3Bb1 genes) and herbicide tolerance (via an EPSPS gene), which was fed to rats for six months. The study investigated the mucosa of the stomach. Alterations to tight junction apposition, gland dilatations with epithelial elongation and dysplasia in the GM-fed rats were observed. These results indicate that GM-corn may have an effect on rat stomach mucosa, which may have health implications.
