Ta_(3)N_(5)/CdS core–shell S-scheme heterojunction nanofibers are fabricated by in situ growing CdS nanodots on Ta_(3)N_(5) nanofib-ers via a simple wet-chemical method.These Ta_(3)N_(5)/CdS nanofibers not only affor...Ta_(3)N_(5)/CdS core–shell S-scheme heterojunction nanofibers are fabricated by in situ growing CdS nanodots on Ta_(3)N_(5) nanofib-ers via a simple wet-chemical method.These Ta_(3)N_(5)/CdS nanofibers not only affords superior photocatalytic tetracycline degradation and mineralization performance,but also cause an efficient photocatalytic Cr(VI)reduction performance.The creation of favorable core–shell fiber-shaped S-scheme hetero-structure with tightly contacted interface and the maximum interface contact area promises the effective photo-carrier disintegration and the optimal photo-redox capacity synchronously,thus leading to the preeminent photo-redox ability.Some critical environmental factors on the photo-behavior of Ta_(3)N_(5)/CdS are also evaluated in view of the complexity of the authentic aquatic environment.The degradation products of tetracycline were confirmed by HPLC–MS analyses.Furthermore,the effective decline in eco-toxicity of TC intermediates is confirmed by QSAR calculation.This work provides cutting-edge guidelines for the design of high-performance Ta_(3)N_(5)-based S-scheme heterojunction nanofibers for environment restoration.展开更多
Hypoxia-inducible factor 1(HIF-1),as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment,participates in many physiological and pathological processes in the body,and is close...Hypoxia-inducible factor 1(HIF-1),as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment,participates in many physiological and pathological processes in the body,and is closely related to the pathogenesis of many diseases.This review outlines the mechanisms of HIF-1 activation,its signaling pathways,natural inhibitors,and its roles in diseases.This article can provide new insights in the diagnosis and treatment of human diseases,and recent progress on the development of HIF-1 inhibitors.展开更多
基金supported by the Natural Science Foundation of Zhejiang Province(LY20E080014)the Science and Technology Project of Zhoushan(2022C41011,2020C21009)the National Natural Science Foundation of China(51708504).
文摘Ta_(3)N_(5)/CdS core–shell S-scheme heterojunction nanofibers are fabricated by in situ growing CdS nanodots on Ta_(3)N_(5) nanofib-ers via a simple wet-chemical method.These Ta_(3)N_(5)/CdS nanofibers not only affords superior photocatalytic tetracycline degradation and mineralization performance,but also cause an efficient photocatalytic Cr(VI)reduction performance.The creation of favorable core–shell fiber-shaped S-scheme hetero-structure with tightly contacted interface and the maximum interface contact area promises the effective photo-carrier disintegration and the optimal photo-redox capacity synchronously,thus leading to the preeminent photo-redox ability.Some critical environmental factors on the photo-behavior of Ta_(3)N_(5)/CdS are also evaluated in view of the complexity of the authentic aquatic environment.The degradation products of tetracycline were confirmed by HPLC–MS analyses.Furthermore,the effective decline in eco-toxicity of TC intermediates is confirmed by QSAR calculation.This work provides cutting-edge guidelines for the design of high-performance Ta_(3)N_(5)-based S-scheme heterojunction nanofibers for environment restoration.
基金supported by the Open Project of State Key Laboratory of Natural Medicines(No.SKLNMKF 202005)the Macao Science and Technology Development Fund(No.071/2017/A2).
文摘Hypoxia-inducible factor 1(HIF-1),as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment,participates in many physiological and pathological processes in the body,and is closely related to the pathogenesis of many diseases.This review outlines the mechanisms of HIF-1 activation,its signaling pathways,natural inhibitors,and its roles in diseases.This article can provide new insights in the diagnosis and treatment of human diseases,and recent progress on the development of HIF-1 inhibitors.
