Objective:To search for further synergistic combinations of gentamicin and raw honey that might have potential in treating wounds.Methods:The antibacterial activity and synergistic interaction of raw honey and gentami...Objective:To search for further synergistic combinations of gentamicin and raw honey that might have potential in treating wounds.Methods:The antibacterial activity and synergistic interaction of raw honey and gentamicin was assessed by using agar well diffusion method.Two Gram-negative(Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 2154)bacteria were selected for antibacterial activity assay.The cultures of bacteria were maintained in their appropriate agar slants at 4°C throughout the study and used as stock cultures.Results:Raw honey and gentamicin interacted synergistically to inhibit Escherichia coli and Pseudomonas aeruginosa.Conclusions:These results suggest that combinations of raw honey and gentamicin have therapeutic benefits in prophylaxis of infections caused by multidrug-resistant Gram-negative bacilli.展开更多
Objective:To investigate the efficacy of unheated and heat-treated Sahara honey on wound healing in rabbits on the basis of macroscopic observation changes.Methods:Eight female rabbits were used.Using aseptic surgical...Objective:To investigate the efficacy of unheated and heat-treated Sahara honey on wound healing in rabbits on the basis of macroscopic observation changes.Methods:Eight female rabbits were used.Using aseptic surgical technique,a 3 cm incision was made on the back of each rabbit and two rabbits with injuries in each group were treated daily with a topical application of unheated and heated honey,sulfadiazine and sterile saline,respectively.Results:The unheated honey demonstrated the highest activity on the wound compared to reference ointment silver sulfadiazine,heat-treated honey and sterile saline respectively.Further the present investigation proves that unheated honey is possessing superior wound healing activity than that of heat-treated honey.Conclusions:The result of this study confirms that unheated honey had the best wound healing effect even better than heat-treated honey.展开更多
基金Supported by Project CNEPRU,Department of Biology University-Abdelhamid IBN Badis-Mostaganem,Algeria(Grant No.N°:F02220120001).
文摘Objective:To search for further synergistic combinations of gentamicin and raw honey that might have potential in treating wounds.Methods:The antibacterial activity and synergistic interaction of raw honey and gentamicin was assessed by using agar well diffusion method.Two Gram-negative(Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 2154)bacteria were selected for antibacterial activity assay.The cultures of bacteria were maintained in their appropriate agar slants at 4°C throughout the study and used as stock cultures.Results:Raw honey and gentamicin interacted synergistically to inhibit Escherichia coli and Pseudomonas aeruginosa.Conclusions:These results suggest that combinations of raw honey and gentamicin have therapeutic benefits in prophylaxis of infections caused by multidrug-resistant Gram-negative bacilli.
基金Supported by project CNEPRU,Institute of Veterinary Sciences,Ibn Khaldoun University(TIARET),Algeria(Grant No.I023201012/2010).
文摘Objective:To investigate the efficacy of unheated and heat-treated Sahara honey on wound healing in rabbits on the basis of macroscopic observation changes.Methods:Eight female rabbits were used.Using aseptic surgical technique,a 3 cm incision was made on the back of each rabbit and two rabbits with injuries in each group were treated daily with a topical application of unheated and heated honey,sulfadiazine and sterile saline,respectively.Results:The unheated honey demonstrated the highest activity on the wound compared to reference ointment silver sulfadiazine,heat-treated honey and sterile saline respectively.Further the present investigation proves that unheated honey is possessing superior wound healing activity than that of heat-treated honey.Conclusions:The result of this study confirms that unheated honey had the best wound healing effect even better than heat-treated honey.
