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Clinical significance of EGF and EGFR expression changes in cryptorchid boys 被引量:2
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作者 YangGS LuRK 《Asian Journal of Andrology》 SCIE CAS CSCD 2002年第4期255-258,共4页
AIM: To explore the changes of epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) expressions in cryptorchid children and their clinical significance. METHODS: The level of serum EGF was measure... AIM: To explore the changes of epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) expressions in cryptorchid children and their clinical significance. METHODS: The level of serum EGF was measured by radioimmunoassay (RIA) and the expression of EGFR by immunohistochemistry. RESULTS: (1) The level of serum EGF was significantly lower in cryptorchid children than in normal subjects at age group of 5-9 years (P 展开更多
关键词 ADOLESCENT Aging Biological Markers CHILD Child Preschool CRYPTORCHIDISM Epidermal Growth Factor Humans IMMUNOHISTOCHEMISTRY Leydig Cells Male Receptor Epidermal Growth Factor
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Spermicidal Effect of Propranolol and Its Isomers onHuman Sperm in vitro
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作者 陆仁康 袁德祥 《Journal of Reproduction and Contraception》 CAS 1995年第1期19-25,共7页
Fourly semen samples were collected from healthy volunteers by masturbation. The samples were then divided into four groups according to the quality and quantity of the sperm. The propranolol (D,L-P) and its isomers i... Fourly semen samples were collected from healthy volunteers by masturbation. The samples were then divided into four groups according to the quality and quantity of the sperm. The propranolol (D,L-P) and its isomers including the Dextko-propranolol (D-P) and LevoAnpropranolol (L-P) solution of various concentrations were tested. SPermicidal e/fect at various intervals was observed by microscopy, and then compared to the Nonoxynol (NP-9) as a reference spermicide.The results showed that the mean values of lowest effective spermicidal concentration of D,L-P, D-P and L-P within twenty seconds were 1.00±0.63,1.10±0.62 and 0.91 ±0.54 (mg/ml) respectively, there was no signijicant difference among them (P>0.05), but they were signilicantly different from that of NP-9 (P<0.001). It is well known that the D- P has no significant beta- adrenoceptor blocking activity, so the D-P might be a new promising vaginal contraceptive drug. 展开更多
关键词 PROPRANOLOL ISOMER SPERMICIDE CONTRACEPTIVE
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