Drawing the Yongquan protocol into the different stages of the cardiopulmonary resuscitation sequence

AIM: To introduce new applications into the ILCORcardiopulmonary resuscitation(CPR) "chain" sequence.METHODS: Stages of the CPR sequence("chain"): prior to the application of chest massage: assess the victim's state of consciousness and lung-heart failure;seek help(call 911), or in situations in which it is impossible to start the ILCOR protocol:(1) if the victim is trapped in car crash, overturned car, landslide, massive number of victims or catastrophe; or(2) delayed CPR.During chest compression: Yongquan is simultaneously stimulated by a third rescuer. During defibrillator application: activate K-1 Yongquan through needles before defibrillation. Unsuccessful CPR: "gold standard"for legal clinical death.RESULTS: Implies comparing two hypotheses: Ho(null hypothesis) demonstrates no association between the two variables studied; Ha(alternative hypothesis) implies some degree of relation between them. Difference between the two treatments is observed. If it is greater than the standard error multiplied by a coefficient of security, the difference is significant: Ha will be accepted and Ho rejected. First we will compare CPR without defibrillator(method "A") and K-1 Yongquan method(method "B"), using percentages of representative samples(treatment "A": 6.4% response, treatment "B": 85% response). If │PA- PB│ is greater than the product of 1.96 times the standard error, the difference is significant. Because │PA- PB│ = 0.786 is greater than 0.098, the difference between 0.064 and 0.85 is statistically significant. Thus, we reject Ho and accept Ha as correct. Thus, it is improbable that chance was responsible for this association. This analysis shows that K-1 Yongquan method has a "quality guarantee". Second, we compare defibrillators("A") with K-1 Yongquan method("B")(treatment "A": 48%, treatment "B": 84%, │PA- PB│= 0.36; │PA- PB│ = 0.36 is greater than SE × 1.96 = 0.0148 and also statistically significant, demonstrating again the comparative value of the Yongquan method. CONCLUSION: The Yongquan resuscitation manoeuver is a non-invasive, non-tiring, costless, and easy-toapply procedure that provides a second chance when other options fail.

皮损类似蕈样肉芽肿的播散性球孢子菌病

This report describes the second known case of disseminated coccidioidomycosis mimicking mycosis fungoides since the original description more than 100 years ago. Coccidioidomycosis should be considered in persons from an endemic area presenting with nonhealing or suspicious skin lesions. Diagnosis is established by skin biopsy and silver staining showing granulomas and classic Coccidioides immitis spherules. Disseminated coccidioidomycosis most commonly involves the skin and can have a variety of cutaneous manifestations. The first description of a Coccidioides immitis infection in 1892 was initially diagnosed as mycosis fungoides. We present the second case of coccidioidomycosis masquerading as mycosis

Torsadogenic Index: Its Chinese Medical Origin

The foundational chronology of Torsadogenic Index is introduced to explain the relationship between impending death situations and drug prescription, combination, self-indication, or abuse of torsadogenic pharmacological products. The pathophysiological basis of Torsade de Pointes is presented with the most frequent causes of Long QT syndrome. Traditional Chinese Medical principles are exposed in order to help people to understand its para-logical sequence, providing another view of medical explanations upon scientific evidence. Development of Torsadogenic Risk Management Project and Torsadogenic Traceability concepts derived from these Chinese Medical perpetual axioms are presented in this paper.

Solitons: A Cutting-Edge Scientific Proposal Explaining the Mechanisms of Acupuntural Action

The Theory of Morphic Fields explains how co-evolution through collective information fields acquires its own organization pattern, nurtured by habits or thoughts that “in-form” the memory of species. The influences of electromagnetic fields (EMFs) on bio-energy transport and its mechanism of changes has been investigated through analytic and numerical simulation as well as experimentation. As an answer to that need Therapeutic Acupunctural Resonance is born. This innovative therapeutic is rooted in concepts from classic Physics as well as Field Quantic Theory—highlighting the practical application of the criterion defined by the Soliton theory and the current, extraordinary discoveries at Cellular Quantic Kinetics level. The development of Therapeutic Acupuntural Resonance has taken into account to a certain extent these concepts: both the compatibility between the Five Element Theory and the principles of Euclidean Geometry, as well as the new forms of interpretation of Quantum mechanisms involved in Cellular Kinetics and its relationship with Chinese Ancient wisdom.

Review of Dimension Reduction Methods

Purpose: This study sought to review the characteristics, strengths, weaknesses variants, applications areas and data types applied on the various Dimension Reduction techniques. Methodology: The most commonly used databases employed to search for the papers were ScienceDirect, Scopus, Google Scholar, IEEE Xplore and Mendeley. An integrative review was used for the study where 341 papers were reviewed. Results: The linear techniques considered were Principal Component Analysis (PCA), Linear Discriminant Analysis (LDA), Singular Value Decomposition (SVD), Latent Semantic Analysis (LSA), Locality Preserving Projections (LPP), Independent Component Analysis (ICA) and Project Pursuit (PP). The non-linear techniques which were developed to work with applications that have complex non-linear structures considered were Kernel Principal Component Analysis (KPCA), Multi-dimensional Scaling (MDS), Isomap, Locally Linear Embedding (LLE), Self-Organizing Map (SOM), Latent Vector Quantization (LVQ), t-Stochastic neighbor embedding (t-SNE) and Uniform Manifold Approximation and Projection (UMAP). DR techniques can further be categorized into supervised, unsupervised and more recently semi-supervised learning methods. The supervised versions are the LDA and LVQ. All the other techniques are unsupervised. Supervised variants of PCA, LPP, KPCA and MDS have been developed. Supervised and semi-supervised variants of PP and t-SNE have also been developed and a semi supervised version of the LDA has been developed. Conclusion: The various application areas, strengths, weaknesses and variants of the DR techniques were explored. The different data types that have been applied on the various DR techniques were also explored.

Acute Hemorrhagic Fever: Clinical, Epidemiological and Laboratory Aspects in São Toméand Príncipe

Background: In the last 6 months, cases of acute hemorrhagic fever (AHF) have been recorded in Sao Tome and Principe (STP). Objective: To identify the clinical, epidemiological and laboratory parameters associated with AHF cases found in patients hospitalized in STP. Methods: Descriptive and quantitative analysis of AHF cases hospitalized in STP in the period December 2021 to May 19, 2022 through the variables: demographic data;clinical data;laboratory data and clinical outcome. Results: Analyzed 18 of 22 AHF cases, 50% of them male, mean age 33.7 years, 85.7% residing in the 2 largest districts of the country, 66.7% rural workers, administrative near maritime areas, sailors and domestics. 66.7% were healthy individuals. ≥50% had a fever, asthenia/weakness, myalgia, headache, lethargy, nausea, vomiting, and diarrhea. 22.2% to 33.3% had retro-orbital pain, abdominal pain, decreased consciousness, dyspnea/hypoxia, and cough. In a smaller register (5.6% - 11.1%), exanthema, convulsion, arthralgia, low back pain, chills, and chest pain. Bleeding from the digestive tract was found in 72.2%, followed by vaginal (33.3%), urethral (27.8%), nasal (22.2%), and oral (16.7%). 50% had laboratory confirmation for dengue, and another 50% with suspected clinical diagnosis without laboratory confirmation of the etiologic agent. Despite hemorrhage, 66.7% of confirmed cases were hemodynamically non-severe, and 88.9% of suspected cases were severe. Coinfection with malaria is evidenced in 11.1% of cases. 72.2% recovered and 27.8% died (deaths in 55.5% of suspected cases). Case deaths were male (100%), resident foreigners (40%), tool store employees, sailors and students, healthy (80%), and residing in the largest district in the country (60%). All deaths were hospitalized in serious condition, 80% were hospitalized for hemorrhage and shock, with bleeding arising between day 4 - 5 of illness in 60% and hospitalization on day 5 of illness. 60% died within ≤24 hours of hospitalization. 80% died from shock and multi-organ dysfunction and 20% from respiratory failure. Deaths had thrombocytopenia (100%), renal dysfunction (100%) and significantly increased transaminases (100%), anemia (75%) and leukocytosis (66.7%). 20% had a radiological change of pulmonary infiltrates. Conclusion: Our data reveal the complexity of the pathogens causing AHF and suggest the possible presence of other human pathogens usually unknown in the Santomean geographical territory.

Forensic imaging:a powerful tool in modern forensic investigation

Forensic imaging is a non-invasive examination process during the forensic investigation.It is mainly used in forensic pathology as an adjunct to the traditional autopsy.In the past two decades,forensic imaging has been vigorously developed by forensic experts from computed tomography(CT)to multiple augmented techniques through CT and magnetic resonance imaging(MRI).The application field of forensic imaging has also been broadened as its advantages are recognised by more forensic practitioners.In addition to the forensic pathology,this technique has been used in other forensic disciplines,including forensic anthropology,forensic odontology,forensic ballistics and wildlife forensics,etc.This article reviews the development of forensic imaging as the practice and research development in different forensic disciplines based on the relevant literature analysis.

Review on the effects of obesity treatment with acupuncture and phytoacupuncture

Objective:The purpose of this study is to review the impact on the usage of traditional Chinese medicine in the treatment of obesity,specifically the usage of acupuncture and phytoacupuncture.Methods:PubMed and Google Scholar databases were searched to identify randomized controlled trials,which the methodology focused on the use of acupuncture and phytoacupuncture for the treatment of obesity from the beginning of these databases to February 2018,supplementing with literature retrospective and manual searches.Results:A total of 8 trials including 566 participants met the selected criteria.In the alterations of the body mass index and waist circumference,acupuncture and phytoacupuncture seems to have a positive effect as opposed to the subjects who received superficial acupuncture or none.However,there were other parameters that showed promising results such as improvements in the levels of(1)serum total cholesterol,low-density lipoprotein and serum fasting triglyceride,(2)serum insulin and leptin,plasma ghrelin and cholecystokinin and(3)serum pro-oxidant antioxidant balance,as well as improvements in(4)skin fat thickness in the upper limbs,trunk and abdomen,(5)abdominal fat and deep subcutaneous fat tissue.The main acupoints employed in the selected studies are found along several meridians such as the stomach,spleen and conception vessel,and the plants used had the main objective of accelerating the metabolism,reducing appetite and resolving the unbalances in the genesis of obesity.Conclusion:It is suggested that acupuncture and phytoacupuncture can be useful tools for weight loss.When combined with a life-style change,they can contribute to achieve better results than just a lifestyle change by itself.Nevertheless,the need for further studies to clarify mechanisms of action and adequacy of protocols in order to obtain more homogeneous results is also present.

A Novel Fine-Grained Method for Vehicle Type Recognition Based on the Locally Enhanced PCANet Neural Network

In this paper, we propose a locally enhanced PCANet neural network for fine-grained classification of vehicles. The proposed method adopts the PCANet unsupervised network with a smaller number of layers and simple parameters compared with the majority of state-of-the-art machine learning methods. It simplifies calculation steps and manual labeling, and enables vehicle types to be recognized without time-consuming training. Experimental results show that compared with the traditional pattern recognition methods and the multi-layer CNN methods, the proposed method achieves optimal balance in terms of varying scales of sample libraries, angle deviations, and training speed. It also indicates that introducing appropriate local features that have different scales from the general feature is very instrumental in improving recognition rate. The 7-angle in 180° （12-angle in 360°） classification modeling scheme is proven to be an effective approach, which can solve the problem of suffering decrease in recognition rate due to angle deviations, and add the recognition accuracy in practice.

A new partnership for an impactful future

Starting from this issue(January,2016),SCIENCE CHINA Life Sciences(SCLS)and The Chinese Biological Investigators Society(CBIS)will embark on a partnership with the goal of making SCLS a highly impactful journal in advancing research in life sciences.

The challenge given by Zika virus

Public health has been a great challenge in many parts of the world,and underdeveloped nations present the greatest challenges in addressing the health problems in the field of public health.In recent years there have been outbreaks of reemerging diseases transmitted by vectors,such as the mosquito,Zika virus disease belonging to this group.Zika virus,which was discovered inciden-tally in Uganda in 1947 in the course of moni-toring mosquitoes and primates,had remained a dark virus confined to a narrow equatorial belt that traversed Africa and Asia[1].Arboreal mosquitoes such as Aedes africanus and rarely caused infections known as“spillage”in humans,even in highly enzootic areas[1].

Perspectives on the Construction of Forensic Autopsy Laboratories Designed to Handle Infectious Diseases

Coronavirus disease 2019 has already infected tens of thousands of people in China.The existing autopsy laboratories are not qualified to perform autopsies on individuals confirmed or suspected to have died from an infectious disease.When dealing with corpses with uncertain health conditions or unknown contact with a pathogen,the forensic medical practitioners face severe risks of being infected.To meet the requirements of performing autopsies on such bodies,ensure the health and safety of forensic medical practitioners,and study the pathophysiological changes of infected patients,it is necessary to improve the construction requirements and regulations for forensic autopsy laboratories.

China Should Develop High-End PS Products

1. Impacts from the financial crisis are still there The global non-expandable polystyrene (PS) production units are mainly distributed in Northeast Asia, North America, WesternEurope, Southeast Asia and South America, (the expandable polystyrene information is not involved in this report) With impacts from the drastic profit reduction in the PS consuming sectors and the appearance of some lowprice substitutes, PS makers suffered some difficulties in operation, even in survival in2009. Some well-known PS producers in the world regrouped and even spun off the PS business. For example, The Dow Chemical shut down its 120 000 t/a PS unit in Zhangjiagang of Jiangsu