Parkinson’s disease(PD)is a movement disorder characterized by reduced dopamine levels due to degeneration of the substantia nigra.The clinical presentation is underlined by bradykinesia,postural instability,and trem...Parkinson’s disease(PD)is a movement disorder characterized by reduced dopamine levels due to degeneration of the substantia nigra.The clinical presentation is underlined by bradykinesia,postural instability,and tremors.PD is the second most common neurodegenerative disease worldwide,with a huge monetary burden.In the United States alone,it is estimated that in 2017,the total economic cost was$51.9 billion,and projected to surpass$79 billion by 2037.Extensive research has been conducted into the pathophysiology and clinical implications of the disease.Within neurodegenerative disorder itself,the entity involving the brain-gut axis has been a fundamental model in understanding the disease process.More so than ever in PD,the association between gut health and neurological disease is gaining momentum,with the fascinating idea of influencing neurological health by treating the gut.展开更多
Patients who suffer a Fractured Neck of Femur (NOF) have a high mortality and morbidity rate with up to 20% needing long term care post fracture and a further 30% not returning to their pre fracture functioning. Hip f...Patients who suffer a Fractured Neck of Femur (NOF) have a high mortality and morbidity rate with up to 20% needing long term care post fracture and a further 30% not returning to their pre fracture functioning. Hip fracture accounts for 87% of total fragility fractures. We describe an anaesthetic technique of fixation of fracture of the femoral neck under direct infiltration local anaesthesia;that can be performed on the sick elderly patient. Twenty-eight NOF fractures were included in this series (24 DHS, 4 Hemiarthroplasty);twenty-three procedures were completed (82.14%);no patient required conversion to another form of anaesthesia either general or spinal;five patients required some degree of light sedation due to agitation (17.8%). This method presents itself as an option in managing patient with high comorbidities which can also be implemented in impoverished areas with limited access to operating surgical facilities.展开更多
Abdominal obesity （AO） has become a major health problem to most of the Asian communities. The severity and consequences of AO are higher among females. It has virtually become an epidemic in most South Asian countr...Abdominal obesity （AO） has become a major health problem to most of the Asian communities. The severity and consequences of AO are higher among females. It has virtually become an epidemic in most South Asian countries and the health care systems in this region are likely to be challenged by one of the biggest health issues in the near future. Yet, the recognition of the magnitude of the problem by health authorities is poor. The purpose of this paper is to motivate health care professionals, planners and policy makers towards better control of the epidemic of AO while highlighting the paucity of evidence on clinical manaclement of AO from the South Asian reqion.展开更多
文摘Parkinson’s disease(PD)is a movement disorder characterized by reduced dopamine levels due to degeneration of the substantia nigra.The clinical presentation is underlined by bradykinesia,postural instability,and tremors.PD is the second most common neurodegenerative disease worldwide,with a huge monetary burden.In the United States alone,it is estimated that in 2017,the total economic cost was$51.9 billion,and projected to surpass$79 billion by 2037.Extensive research has been conducted into the pathophysiology and clinical implications of the disease.Within neurodegenerative disorder itself,the entity involving the brain-gut axis has been a fundamental model in understanding the disease process.More so than ever in PD,the association between gut health and neurological disease is gaining momentum,with the fascinating idea of influencing neurological health by treating the gut.
文摘Patients who suffer a Fractured Neck of Femur (NOF) have a high mortality and morbidity rate with up to 20% needing long term care post fracture and a further 30% not returning to their pre fracture functioning. Hip fracture accounts for 87% of total fragility fractures. We describe an anaesthetic technique of fixation of fracture of the femoral neck under direct infiltration local anaesthesia;that can be performed on the sick elderly patient. Twenty-eight NOF fractures were included in this series (24 DHS, 4 Hemiarthroplasty);twenty-three procedures were completed (82.14%);no patient required conversion to another form of anaesthesia either general or spinal;five patients required some degree of light sedation due to agitation (17.8%). This method presents itself as an option in managing patient with high comorbidities which can also be implemented in impoverished areas with limited access to operating surgical facilities.
文摘Abdominal obesity （AO） has become a major health problem to most of the Asian communities. The severity and consequences of AO are higher among females. It has virtually become an epidemic in most South Asian countries and the health care systems in this region are likely to be challenged by one of the biggest health issues in the near future. Yet, the recognition of the magnitude of the problem by health authorities is poor. The purpose of this paper is to motivate health care professionals, planners and policy makers towards better control of the epidemic of AO while highlighting the paucity of evidence on clinical manaclement of AO from the South Asian reqion.
