Objective To investigate the clinical efficacy of allogeneic hematopoietic stem cell transplantation(allo-HSCT)for patients with acute leukemia who are positive for the SET-NUP214 fusion gene(SET-NUP214^(+)AL).Methods...Objective To investigate the clinical efficacy of allogeneic hematopoietic stem cell transplantation(allo-HSCT)for patients with acute leukemia who are positive for the SET-NUP214 fusion gene(SET-NUP214^(+)AL).Methods This was a retrospective case series study.展开更多
Objective To investigate the survival and prognosis of B-lineage acute lymphoblastic leukemia (B-ALL) patients with TP53 mutation.Methods The clinical data of 479 newly diagnosed B-ALL patients treated in the First Af...Objective To investigate the survival and prognosis of B-lineage acute lymphoblastic leukemia (B-ALL) patients with TP53 mutation.Methods The clinical data of 479 newly diagnosed B-ALL patients treated in the First Affiliated Hospital of Soochow University from January 2016 to December 2019 were retrospectively analyzed.展开更多
Objective To investigate the effects of iron chelation therapy on hematopoietic reconstitution and related complications of allogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with myelodysplastic...Objective To investigate the effects of iron chelation therapy on hematopoietic reconstitution and related complications of allogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with myelodysplastic syndrome(MDS).Methods Various clinical parameters were analyzed retrospectively in 57 MDS patients展开更多
Objective To study KIR3DL1 expression level on NK cell surface of normal donors for hematopoietic stem cell transplantation(HSCT).Methods Ninety-two donors were performed by using of KIR genotyping,HLA high resolution...Objective To study KIR3DL1 expression level on NK cell surface of normal donors for hematopoietic stem cell transplantation(HSCT).Methods Ninety-two donors were performed by using of KIR genotyping,HLA high resolution genotyping and KIR3DL1 expression level using sequence-based testing(SBT),PCR-sequence specific primer(SSP)and flow cytometry methods.Results In 92 donors,the frequencies of KIR-A/A,Bx1。展开更多
Objective To investigate the survival and prognostic factors of allogeneic hematopoietic stem-cell transplantation (allo-HSCT) for patients with myeloid neoplasms and RUNX1 mutations.
Objective To analyze allele mismatches of HLA-A,-B,-C,-DRB1,-DQB1 and haplotype mismatch of donor-recipient pairs on the outcome of haploidentical transplantation combined with a third part cord blood unit.Methods 230...Objective To analyze allele mismatches of HLA-A,-B,-C,-DRB1,-DQB1 and haplotype mismatch of donor-recipient pairs on the outcome of haploidentical transplantation combined with a third part cord blood unit.Methods 230 pairs of donor-recipient were performed HLA-A,B,C,DRB1,DQB1 typing using展开更多
文摘Objective To investigate the clinical efficacy of allogeneic hematopoietic stem cell transplantation(allo-HSCT)for patients with acute leukemia who are positive for the SET-NUP214 fusion gene(SET-NUP214^(+)AL).Methods This was a retrospective case series study.
文摘Objective To investigate the survival and prognosis of B-lineage acute lymphoblastic leukemia (B-ALL) patients with TP53 mutation.Methods The clinical data of 479 newly diagnosed B-ALL patients treated in the First Affiliated Hospital of Soochow University from January 2016 to December 2019 were retrospectively analyzed.
文摘Objective To investigate the effects of iron chelation therapy on hematopoietic reconstitution and related complications of allogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with myelodysplastic syndrome(MDS).Methods Various clinical parameters were analyzed retrospectively in 57 MDS patients
文摘Objective To study KIR3DL1 expression level on NK cell surface of normal donors for hematopoietic stem cell transplantation(HSCT).Methods Ninety-two donors were performed by using of KIR genotyping,HLA high resolution genotyping and KIR3DL1 expression level using sequence-based testing(SBT),PCR-sequence specific primer(SSP)and flow cytometry methods.Results In 92 donors,the frequencies of KIR-A/A,Bx1。
文摘Objective To investigate the survival and prognostic factors of allogeneic hematopoietic stem-cell transplantation (allo-HSCT) for patients with myeloid neoplasms and RUNX1 mutations.
文摘Objective To analyze allele mismatches of HLA-A,-B,-C,-DRB1,-DQB1 and haplotype mismatch of donor-recipient pairs on the outcome of haploidentical transplantation combined with a third part cord blood unit.Methods 230 pairs of donor-recipient were performed HLA-A,B,C,DRB1,DQB1 typing using
