The title compound, （4R,5R）-1,3-dioxolance-4,5-bis（2-pyridineacrboxylic acid）, has been synthesized and characterized by single-crystal X-ray diffraction, IR, NMR, and MS analyses. Crystal structure of the title c...The title compound, （4R,5R）-1,3-dioxolance-4,5-bis（2-pyridineacrboxylic acid）, has been synthesized and characterized by single-crystal X-ray diffraction, IR, NMR, and MS analyses. Crystal structure of the title compound was grown from ETOH by slow diffusion at room temperature. The title compound crystallizes in monoclinic, space group C2 with a = 17.805（3）, b = 11.459（3）, c = 11.1656（17） , β = 113.066（4）°, V = 2095.9（6） 3, Z = 4, F（000） = 880, Dc = 1.332 Mg/m-3, C23H20N2O6, Mr = 420.41 and μ = 0.10 mm-1展开更多
The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst...The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst,potassium persulfate as a co-oxidant,which can afford the arylated products in mild to good yields.The mechanism is presumed to proceed through a nucleophilic radical addition to the pyridines with in situ reoxidation.展开更多
基金Supported by the NNSFC (20872051)Foundation of Jiangsu Provincial Key Laboratory of Fine Petrochemical Technology (KF0807)
文摘The title compound, （4R,5R）-1,3-dioxolance-4,5-bis（2-pyridineacrboxylic acid）, has been synthesized and characterized by single-crystal X-ray diffraction, IR, NMR, and MS analyses. Crystal structure of the title compound was grown from ETOH by slow diffusion at room temperature. The title compound crystallizes in monoclinic, space group C2 with a = 17.805（3）, b = 11.459（3）, c = 11.1656（17） , β = 113.066（4）°, V = 2095.9（6） 3, Z = 4, F（000） = 880, Dc = 1.332 Mg/m-3, C23H20N2O6, Mr = 420.41 and μ = 0.10 mm-1
基金We are thankful for the financial support of“National Natural Science Foundation of China(21302014)”“Program of Applied Basic Research in Changzhou(CJ20130003)”“Open Project of Jiangsu Province Key Laboratory of Fine Petrochemical Engineering(KF1304)”.
文摘The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst,potassium persulfate as a co-oxidant,which can afford the arylated products in mild to good yields.The mechanism is presumed to proceed through a nucleophilic radical addition to the pyridines with in situ reoxidation.
