Background: Diagnostic investigation of dementia is based on a series of tests which lie the neuropsychological evaluations. The Montreal Cognitive Assessment (MoCA) was developed as an instrument to recognize Mild Co...Background: Diagnostic investigation of dementia is based on a series of tests which lie the neuropsychological evaluations. The Montreal Cognitive Assessment (MoCA) was developed as an instrument to recognize Mild Cognitive Impairment (MCI) and initial cases of Alzheimer’s disease. The present study aims to evaluate the predictive value of Brazilian MoCA test version in a sample of elderly above 5 years of education. Methods: Cross-sectional study with 136 elderly, above 60 years old at least 5 years of education. Diagnostic criteria is based on clinical and neuropsychological data classified Alzheimer’s disease n = 52, MCI n = 45 e normal controls n = 39. MoCA test was compared with Cambridge Cognitive Examination, Mini-Mental State Exam, Verbal Fluency, Clock Drawing Test, Geriatric Depression Scale and Pfeffer Functional Activities Questionnaire. Accuracy was evaluated by receiver operating characteristic (ROC) curve analyses. Pearson correlation coefficient was used to compare the MoCA with the other tests. It was also used logistic regression analysis to identify the main risk factors for the diagnostic groups. Results: MoCA was the best test to differentiate Alzheimer’s disease cases from MCI with 86.5% sensitivity and 75.6% specificity. Furthermore, analyzes of correlation test showed that MoCA correlates robust way of already validated with other tests and wide application inBrazil. Conclusions: It can be concluded that MoCA is a good screening tool for investigation of MCI among the elderly in Brazil with over 5 years of schooling. Studies with larger numbers of participants are needed to further validate the test also for elderly people with low education.展开更多
Research on cognitive aging is becoming increasingly common because aging is a global phenomenon and brings with it many challenges, for example, the increased incidence of dementias such as Alzheimer’s Disease (AD)....Research on cognitive aging is becoming increasingly common because aging is a global phenomenon and brings with it many challenges, for example, the increased incidence of dementias such as Alzheimer’s Disease (AD). Even if the cognitive decline in AD is apparently linear, impairment of autonomy in activities of daily living does not follow the same pattern. Objectives: To monitor and evaluate the cognitive aspects of elderly diagnosed with Alzheimer’s disease. Methodological procedures: This research was conducted from January 2006 to July 2013 at the Clinic of Geriatrics and Gerontology. Longitudinal study of 51 elderly patients aged 60 years, of both sexes who received a diagnosis of Alzheimer’s disease by DSM-IV (APA, 1994) and NINDS-ADRDA (McKhann et al., 2011). Results: From the results obtained in the present study, we observed that the participants had a decline in cognitive function from the first to the second assessment, even with drug treatment.展开更多
文摘Background: Diagnostic investigation of dementia is based on a series of tests which lie the neuropsychological evaluations. The Montreal Cognitive Assessment (MoCA) was developed as an instrument to recognize Mild Cognitive Impairment (MCI) and initial cases of Alzheimer’s disease. The present study aims to evaluate the predictive value of Brazilian MoCA test version in a sample of elderly above 5 years of education. Methods: Cross-sectional study with 136 elderly, above 60 years old at least 5 years of education. Diagnostic criteria is based on clinical and neuropsychological data classified Alzheimer’s disease n = 52, MCI n = 45 e normal controls n = 39. MoCA test was compared with Cambridge Cognitive Examination, Mini-Mental State Exam, Verbal Fluency, Clock Drawing Test, Geriatric Depression Scale and Pfeffer Functional Activities Questionnaire. Accuracy was evaluated by receiver operating characteristic (ROC) curve analyses. Pearson correlation coefficient was used to compare the MoCA with the other tests. It was also used logistic regression analysis to identify the main risk factors for the diagnostic groups. Results: MoCA was the best test to differentiate Alzheimer’s disease cases from MCI with 86.5% sensitivity and 75.6% specificity. Furthermore, analyzes of correlation test showed that MoCA correlates robust way of already validated with other tests and wide application inBrazil. Conclusions: It can be concluded that MoCA is a good screening tool for investigation of MCI among the elderly in Brazil with over 5 years of schooling. Studies with larger numbers of participants are needed to further validate the test also for elderly people with low education.
文摘Research on cognitive aging is becoming increasingly common because aging is a global phenomenon and brings with it many challenges, for example, the increased incidence of dementias such as Alzheimer’s Disease (AD). Even if the cognitive decline in AD is apparently linear, impairment of autonomy in activities of daily living does not follow the same pattern. Objectives: To monitor and evaluate the cognitive aspects of elderly diagnosed with Alzheimer’s disease. Methodological procedures: This research was conducted from January 2006 to July 2013 at the Clinic of Geriatrics and Gerontology. Longitudinal study of 51 elderly patients aged 60 years, of both sexes who received a diagnosis of Alzheimer’s disease by DSM-IV (APA, 1994) and NINDS-ADRDA (McKhann et al., 2011). Results: From the results obtained in the present study, we observed that the participants had a decline in cognitive function from the first to the second assessment, even with drug treatment.
