During pursuit eye movements, whether the relationships among the visual sensitivity, pursuit velocity, and target velocity are linear or non-linear is an old issue. In this study, we reexamined their relationships wi...During pursuit eye movements, whether the relationships among the visual sensitivity, pursuit velocity, and target velocity are linear or non-linear is an old issue. In this study, we reexamined their relationships with seven speeds by a simple character discrimination task using an infrared eye tracker. Our results found that the pursuit velocity and accuracy were non-linearly related with the target velocity. Besides, the perceptual sensitivity was not linearly related with the pursuit velocity either. A significant difference existed between lower (less than 20 deg/s) and higher speeds (greater than 20 deg/s). In addition, we found there was no position bias of visual sensitivity between ahead of and behind the pursuit target, but there was a significant perceptual dissymmetry between horizontal and vertical directions at lower pursuit speeds.展开更多
Understanding how neural circuits contribute to cognitive differences between humans and other species, including macaque monkeys, is a major issue in neuroscience. Lan- guage and tool use are the most prominent diffe...Understanding how neural circuits contribute to cognitive differences between humans and other species, including macaque monkeys, is a major issue in neuroscience. Lan- guage and tool use are the most prominent differences be- tween humans and other primates. Many neuroimag- ing-based studies have explored the brain mechanisms un- derlying language to reveal the origin of human evolution. Leroy et al. found human-specific asymmetry in the superi- or temporal sulcus (STS) by analyzing the magnetic reso- nance images (MRI) of humans and chimpanzees [1[, and resting-state functional connectivity analyses have revealed that the functional coupling between the posterior superior temporal gyrus (STG) and inferior frontal gyrus (IFG) is more prominent in humans than in macaques [2].展开更多
Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has man...Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has many poten- tial applications in human medicine, with the advantage of having few side effects (Keen, 2012). Investigating the mechanisms of bacteria-killing phages will therefore aid in the development of antibacterial drugs.展开更多
A sensory stimulus can only be properly interpreted in light of the stimuli that surround it in space and time. The tilt illusion (TI) and tilt after-effect (TAE) provide good evidence that the perception of a tar...A sensory stimulus can only be properly interpreted in light of the stimuli that surround it in space and time. The tilt illusion (TI) and tilt after-effect (TAE) provide good evidence that the perception of a target depends strongly on both its spatial and temporal context. In previous studies, the TI and TAE have typically been investigated separately, so little is known about their co-effects on visual perception and information processing mechanisms. Here, we considered the influence of the spatial context and the temporal effect together and asked how center- surround context affects the TAE in foveal and para- foveal vision. Our results showed that different center-surround spatial patterns significantly affected the TAE for both foveal and para-foveal vision. In the fovea, the TAE was mainly produced by central adaptive gratings. Cross-oriented surroundings significantly inhibited the TAE, and iso-oriented surroundings slightly facilitated it; surround inhibition was much stronger than surround facilitation. In the para-fovea, the TAE was mainly decided by the surrounding patches. Likewise, a cross-oriented central patch inhibited the TAE, and an iso-oriented one facilitated it, but there was no significant difference between inhibition and facilitation. Our findings demonstrated, at the perceptual level, that our visual system adopts different mechanisms to process consistent or inconsistent central-surround orientation information and that the unequalmagnitude of surround inhibition and facilitation is vitally important for the visual system to improve the detectability or discriminability of novel or incongruent stimuli.展开更多
基金supported by the National Natural Science Foundation of China under Grant No.60972108,91120013,61375115,31300912973 Project under Grant No.2013CB329401+1 种基金Key Technology Research&Development Programs of Sichuan Province under Grant No.2011GZ0073the Fundamental Research Funds for the Central Universities under Grant No.ZYGX2013J098,ZYGX2011X017
文摘During pursuit eye movements, whether the relationships among the visual sensitivity, pursuit velocity, and target velocity are linear or non-linear is an old issue. In this study, we reexamined their relationships with seven speeds by a simple character discrimination task using an infrared eye tracker. Our results found that the pursuit velocity and accuracy were non-linearly related with the target velocity. Besides, the perceptual sensitivity was not linearly related with the pursuit velocity either. A significant difference existed between lower (less than 20 deg/s) and higher speeds (greater than 20 deg/s). In addition, we found there was no position bias of visual sensitivity between ahead of and behind the pursuit target, but there was a significant perceptual dissymmetry between horizontal and vertical directions at lower pursuit speeds.
文摘Understanding how neural circuits contribute to cognitive differences between humans and other species, including macaque monkeys, is a major issue in neuroscience. Lan- guage and tool use are the most prominent differences be- tween humans and other primates. Many neuroimag- ing-based studies have explored the brain mechanisms un- derlying language to reveal the origin of human evolution. Leroy et al. found human-specific asymmetry in the superi- or temporal sulcus (STS) by analyzing the magnetic reso- nance images (MRI) of humans and chimpanzees [1[, and resting-state functional connectivity analyses have revealed that the functional coupling between the posterior superior temporal gyrus (STG) and inferior frontal gyrus (IFG) is more prominent in humans than in macaques [2].
基金supported by the National Nature Scientific Foundation of China(No.61301260)the Applied Basic Research Program of Sichuan Province(No.2015JY0100 and LZ-LY-45)+3 种基金the Scientific Research Foundation of the Education Department of Sichuan Province(11ZB122)the Nature Scientific Foundation of Hebei Province(No.C2013209105)the Fundamental Research Funds for the Central Universities of China(No.ZYGX2015J144,ZYGX2015Z006)Program for the Top Young Innovative Talents of Higher Learning Institutions of Hebei Province(No.BJ2014028)
文摘Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has many poten- tial applications in human medicine, with the advantage of having few side effects (Keen, 2012). Investigating the mechanisms of bacteria-killing phages will therefore aid in the development of antibacterial drugs.
基金supported by the National Basic Research Development Program of China ( 2013CB329401)National High Technology Development Program (863 Program) of China (2015AA020505)+2 种基金the National Natural Science Foundation of China (91120013, 6 1375115, 3 1300912, and 31100797)the 111 Project (B12027)F undamental Research Funds for the C entral Universities of China (Z YGX2013J098)
文摘A sensory stimulus can only be properly interpreted in light of the stimuli that surround it in space and time. The tilt illusion (TI) and tilt after-effect (TAE) provide good evidence that the perception of a target depends strongly on both its spatial and temporal context. In previous studies, the TI and TAE have typically been investigated separately, so little is known about their co-effects on visual perception and information processing mechanisms. Here, we considered the influence of the spatial context and the temporal effect together and asked how center- surround context affects the TAE in foveal and para- foveal vision. Our results showed that different center-surround spatial patterns significantly affected the TAE for both foveal and para-foveal vision. In the fovea, the TAE was mainly produced by central adaptive gratings. Cross-oriented surroundings significantly inhibited the TAE, and iso-oriented surroundings slightly facilitated it; surround inhibition was much stronger than surround facilitation. In the para-fovea, the TAE was mainly decided by the surrounding patches. Likewise, a cross-oriented central patch inhibited the TAE, and an iso-oriented one facilitated it, but there was no significant difference between inhibition and facilitation. Our findings demonstrated, at the perceptual level, that our visual system adopts different mechanisms to process consistent or inconsistent central-surround orientation information and that the unequalmagnitude of surround inhibition and facilitation is vitally important for the visual system to improve the detectability or discriminability of novel or incongruent stimuli.