Panel Discussion on“Development Trends of Computer Science in the New Era”

At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in the field.6 heads of university computer science departments participated in the discussions,including the moderator,Professor Andrew Yao.The first issue was how universities are managing the growing number of applicants in addition to swelling class sizes.Several approaches were suggested,including increasing faculty hiring,implementing scalable teaching tools,and working closer with other departments through degree programs that integrate computer science with other fields.The second issue was about the position and role of computer science within broader science.Participants generally agreed that all fields are increasingly relying on computer science techniques,and that effectively disseminating these techniques to others is a key to unlocking broader scientific progress.

Elucidating the evolution of long-period stacking ordered phase and its effect on deformation behavior in the as-cast Mg-6Gd-1Zn-0.6Zr alloy

Herein,the evolution of long-period stacking ordered(LPSO)phases in the as-cast Mg-6Gd-1Zn-0.6Zr(wt.%)alloy are investigated via transmission electron microscopy(TEM)and atom probe tomography(APT).The TEM results reveal that two types of LPSO phase(a bulky interdendritic phase and a plate-like matrix LPSO phase)are formed in the as-cast sample.Most of the LPSO phases are confirmed to be of the 14H type,with a smaller proportion being of the 18R LPSO.Further,the APT results reveal that the composition of the interdendritic LPSO phase is closer to that of the ideal 14H phase compared to the matrix LPSO phase,and both the interdendritic and matrix LPSO phases exhibit a Gd/Zn ratio of 2.5,thereby indicating a deficient Zn content compared to the ideal 14H phase(i.e.,1.3).In addition,the influence of the LPSO phases on the deformation behavior is investigated at different compressive plastic strains using electron backscatter diffraction(EBSD)analysis to reveal twinning and slip behavior during deformation.The results indicate that the LPSO phase induces additional work hardening in the late stage of deformation via the suppression of{1011}compressive twinning and the activation of non-basal slip systems.

Helping People and Changing the World with CS

What should academic institutions be doing in order to benefit students,the community at large,and society in the new era?Particularly,as computing is impacting all aspects of human society,it also brings many challenges and opportunities for the academic departments of computer science.Some of these challenges include the increasing impact of software on society,issues involving privacy and data abuse,and ethical issues concerning AI.Towards addressing these challenges,the Korea Advanced Institute of Science and Technology(KAIST)leverages its position as an educator in order to train the future computing workforce to be more aware of these issues.To achieve this goal,KAIST mainly adopts three strategies:Combining science&technology and humanities together;putting academy and industry together;training software experts while making them understand people and the world.

Distinction of white,beige and brown adipocytes derived from mesenchymal stem cells

Adipose tissue is a major metabolic organ, and it has been traditionally classified as either white adipose tissue(WAT) or brown adipose tissue(BAT). WAT and BAT are characterized by different anatomical locations, morphological structures, functions, and regulations. WAT and BAT are both involved in energy balance. WAT is mainly involved in the storage and mobilization of energy in the form of triglycerides, whereas BAT specializes in dissipating energy as heat during cold- or diet-induced thermogenesis. Recently, brownlike adipocytes were discovered in WAT. These brownlike adipocytes that appear in WAT are called beige or brite adipocytes. Interestingly, these beige/brite cells resemble white fat cells in the basal state, but they respond to thermogenic stimuli with increased levels of thermogenic genes and increased respiration rates. In addition, beige/brite cells have a gene expressionpattern distinct from that of either white or brown fat cells. The current epidemic of obesity has increased the interest in studying adipocyte formation(adipogenesis), especially in beige/brite cells. This review summarizes the developmental process of adipose tissues that originate from the mesenchymal stem cells and the features of these three different types of adipocytes.

Numerical simulation on the microstress and microstrain of low Si-Mn-Nb dual-phase steel

根据单相的马氏体和单相的铁酸盐钢的压力紧张曲线，其作文在低 Si-Mn-Nb 双阶段的钢类似于马氏体和铁酸盐的那些，低 Si-Mn-Nb 双阶段的钢的压力紧张曲线用模仿的结果与测量的那相比的有限元素 methodFEM.The 被模仿，他们与对方一起仔细适合，它证明 FE 模型是 dual-pha 的 FE 模型， microstress 和 microstrain 上的 correct.Based 同时，象马氏体和收益的体积部分那样的有效因素强调在双阶段的钢的压力紧张曲线上的马氏体和铁酸盐阶段之间的比率被模仿，模仿的 too.The 结果显示为低 Si-Mn-Nb 双阶段的钢，最大的压力发生在马氏体区域，当最大的紧张在双阶段的 s 的压力紧张曲线上发生在 martensitefm 和收益压力比率的体积部分的铁酸盐 one.The

Integrated design optimization of composite frames and materials for maximum fundamental frequency with continuous fiber winding angles

Fiber reinforced composite frame structure is an ideal lightweight and large-span structure in the fields of aerospace,satellite and wind turbine.Natural fundamental frequency is one of key indicators in the design requirement of the composite frame since structural resonance can be effectively avoided with the increase of the fundamental frequency.Inspired by the concept of integrated design optmization of composite frame structures and materials,the design optimization for the maximum structural fundamental frequency of fiber reinforced frame structures is proposed.An optimization model oriented at the maximum structural fundamental frequency under a composite material volume constraint is established.Two kinds of independent design variables are optimized,in which one is variables represented structural topology,the other is variables of continuous fiber winding angles.Sensitivity analysis of the frequency with respect to the two kinds of independent design variables is implemented with the semi-analytical sensitivity method.Some representative examples in the manuscript demonstrate that the integrated design optimization of composite structures can effectively explore coupled effects between structural configurations and material properties to increase the structural fundamental frequency.The proposed integrated optimization model has great potential to improve composite frames structural dynamic performance in aerospace industries.

Degradation behaviors,thermostability and mechanical properties of poly(ethylene terephthalate)/polylactic acid blends

It is difficult for polyethylene terephthalate(PET)to degrade,which caused severe pollution.In this work,polylactic acid(PLA)was introduced to improve the degradation of PET.PET/PLA was synthesized by extrusion blending.The thermal,crystalline and mechanical properties of blends were investigated with TGA,DSC,WAXD and universal testing machine.The degradation of the blends in soil,acid and alkaline buffer solutions was assessed,respectively.It was found that the introduction of a little PLA promoted crystallization of PET during injection molding process.The starting decomposition temperature lowered from 412.1 °C of pure PET to 330.4 °C at 50% PLA content,tensile and bending strength of blends gradually decreased with the PLA content increasing,while the degradation rate improved.Alkaline environment was most beneficial for blends to degrade.The degradation mechanism was discussed.

Recent advances in lithographic fabrication of micro-/nanostructured polydimethylsiloxanes and their soft electronic applications

The intensive development of micro-/nanotechnologies offers a new route to construct sophisticated architectures of emerging soft electronics.Among the many classes of stretchable materials,micro-/nanostructured poly(dimethylsiloxane)(PDMS)has emerged as a vital building block based on its merits of flexibility,stretchability,simple processing,and,more importantly,high degrees of freedom of incorporation with other functional materials,including metals and semiconductors.The artificially designed geometries play important roles in achieving the desired mechanical and electrical performances of devices and thus show great potential for applications in the fields of stretchable displays,sensors and actuators as well as in health-monitoring device platforms.Meanwhile,novel lithographic methods to produce stretchable platforms with superb reliability have recently attracted research interest.The aim of this review is to comprehensively summarize the progress regarding micro-/nanostructured PDMS and their promising soft electronic applications.This review is concluded with a brief outlook and further research directions.

Synthesis of Nano-sized Barium Titanate Powder by Solid-state Reaction between Barium Carbonate and Titania

BaTiO3 在的尺寸控制固态在 BaCO3 和 TiO2 之间的反应被改变更高有的 BaCO3.The 更小的 TiO2 粒子的 TiO2 和 milling 条件的尺寸表明表面区域，导致更快的起始的反应。机械地， milled BaCO3 粒子加速了散开过程并且减少锻烧温度。它能从结果被推出尺寸控制可能、缩放 nano 有大约 60 nm 的 BaTiO3 粒子能被使用综合常规固态在 BaCO3 和 TiO2 之间的反应。

Effects of Flexible Conjugation-Break Spacers of Non-Conjugated Polymer Acceptors on Photovoltaic and Mechanical Properties of All-Polymer Solar Cells

All-polymer solar cells(all-PSCs)possess attractive merits including superior thermal stability and mechanical flexibility for large-area roll-to-roll processing.Introducing flexible conjugation-break spacers(FCBSs)into backbones of polymer donor(P_(D))or polymer acceptor(P_(A))has been demonstrated as an efficient approach to enhance both the photovoltaic(PV)and mechanical properties of the all-PSCs.However,length dependency of FCBS on certain all-PSC related properties has not been systematically explored.In this regard,we report a series of new non-conjugated P_(A)s by incorporating FCBS with various lengths(2,4,and 8 carbon atoms in thioalkyl segments).Unlike com-mon studies on so-called side-chain engineering,where longer side chains would lead to better solubility of those resulting polymers,in this work,we observe that the solubilities and the resulting photovoltaic/mechanical properties are optimized by a proper FCBS length(i.e.,C2)in P_(A) named PYTS-C2.Its all-PSC achieves a high efficiency of 11.37%,and excellent mechanical robustness with a crack onset strain of 12.39%,significantly superior to those of the other P_(A)s.These results firstly demonstrate the effects of FCBS lengths on the PV performance and mechanical properties of the all-PSCs,providing an effective strategy to fine-tune the structures of P_(A)s for highly efficient and mechanically robust PSCs.

Toward Data-Driven Digital Therapeutics Analytics:Literature Review and Research Directions

With the advent of digital therapeutics(DTx),the development of software as a medical device(SaMD)for mobile and wearable devices has gained significant attention in recent years.Existing DTx evaluations,such as randomized clinical trials,mostly focus on verifying the effectiveness of DTx products.To acquire a deeper understanding of DTx engagement and behavioral adherence,beyond efficacy,a large amount of contextual and interaction data from mobile and wearable devices during field deployment would be required for analysis.In this work,the overall flow of the data-driven DTx analytics is reviewed to help researchers and practitioners to explore DTx datasets,to investigate contextual patterns associated with DTx usage,and to establish the(causal)relationship between DTx engagement and behavioral adherence.This review of the key components of datadriven analytics provides novel research directions in the analysis of mobile sensor and interaction datasets,which helps to iteratively improve the receptivity of existing DTx.

Unassisted overall water splitting with a solar-to-hydrogen efficiency of over 10% by coupled lead halide perovskite photoelectrodes

Hydrogen is a promising future sustainable fuel candidate with boundless opportunities.Research into photoelectrochemical(PEC)water splitting based on a lead halide perovskite(LHP)has progressed significantly with the aim of more efficient solar hydrogen production.Herein,we unite a well-known photo-absorbing LHP with cost-effective water-splitting catalysts,and we introduce two types of monolithic LHP-based PEC devices that act as a photocathode and a photoanode for the hydrogen evolution reaction and oxygen evolution reaction,leading to efficient unbiased overall water splitting.Through the integration of these two monolithic LHP-based photoelectrodes,an unbiased solar-to-hydrogen conversion efficiency of 10.64%and a photocurrent density of 8.65 mA cm^(−2) are achieved.

Detection of the Single Image from DIBR Based on 3D Warping Trace and Edge Matching

Recently, the popularity of 3D content is on the rise because of its immersive experience to view- ers. While demands for 3D contents and 3D technologies increase, only a few copyright protection methods for 3D contents have been proposed. The simplest infringement is the illegal distribution of the single 2D image from 3D content. The leaked image is still valuable as 2D content and the leakage can be occurred in DIBR system. To detect the leaked image, we focus on the hole-filled region which is caused by the hole-filling procedure mandatory in DIBR system. To estimate the hole-filled regions, two different procedures are conducted to extract edges and to estimate 3D warping traces, respectively. After that, the hole-filled regions are estimated and the left-right-eye image discrimination (LR discrimination) is also conducted. Experimental results demonstrate the effectiveness of the proposed method using quantitative measures.

Analysis of Bell-Type Experiments and Its Local Realism

We investigate the violation factor of the original Bell-Mermin inequality. Until now, we have used an assumption that the results of measurement are . In this case, the maximum violation factor is as follows: and . The quantum predictions by n-partite Greenberger-Horne-Zeilinger state violate the Bell-Mermin inequality by an amount that grows exponentially with n. Recently, a new measurement theory is proposed [K. Nagata and T. Nakamura, International Journal of Theoretical Physics, 49, 162 (2010)]. The values of measurement outcome are . Here we use the new measurement theory. We consider a multipartite GHZ state. We use the original Bell-Mermin inequality. It turns out that the original Bell-Mermin inequality is satisfied irrespective of the number of particles. In this case, the maximum violation factor is as follows: and . Thus the original Bell-Mermin inequality is satisfied by the new measurement theory. We propose the following conjecture: All the two-orthogonal-settings experimental correlation functions admit local realistic theories irrespective of a state if we use the new measurement theory.

Self Consistent Calibration of Detectors and Sources for Hard and Soft X-Ray Diagnostics

X-Ray sources, detectors and optical components are now used in a wide range of applications. What is crucial is the absolute calibration of such devices to permit a quantitative assessment of the system under study. A new X-ray laboratory has been built in Frascati (ENEA) to develop diagnostics for nuclear fusion experiments and study applications of these X-ray techniques in other domains, like new material science, non destructive tests and so on. An in-house developed selfconsistent calibration procedure is described that permits the absolute calibration of sources (X-ray emitted fluxes) and detectors (detection efficiencies) as function of the X-ray photon energy, in the range 2 - 120 keV. The calibration procedure involves the use of an in-house developed code that also predicts the spectral response of any detector in any experimental condition that can be setup in the laboratory. The procedure has been then applied for the calibration and characterisation of gas and solid state imaging detectors, such as Medipix-2, GEM gas detector, CCD camera, Cd-Te C-MOS imager, demonstrating the versatility of the method developed here.

Microglia and astrocytes mediate synapse engulfment in a MER tyrosine kinase-dependent manner after traumatic brain injury

Recent studies have shown that microglia/macrophages and astrocytes can mediate synaptic phagocytosis through the MER proto-oncokinase in developmental or stroke models,but it is unclear whether the same mechanism is also active in traumatic brain injury.In this study,we established a mouse model of traumatic brain injury and found that both microglia/macrophages and astrocytes phagocytosed synapses and expression of the MER proto-oncokinase increased 14 days after injury.Specific knockout of MER in microglia/macrophages or astrocytes markedly reduced injury volume and greatly improved neurobehavioral function.In addition,in both microglia/macrophages-specific and astrocytes-specific MER knock-out mice,the number of microglia/macrophage and astrocyte phagocytosing synapses was markedly decreased,and the total number of dendritic spines was increased.Our study suggested that MER proto-oncokinase expression in microglia/macrophages and astrocytes may play an important role in synaptic phagocytosis,and inhibiting this process could be a new strategy for treating traumatic brain injury.

(EDTA)^(4-) supplements as superior modifier of the in-vitro-degradation properties of the magnesium alloy coated through discharge-assisted process

The(EDTA)^(4-)organic substituents were supplemented with alkaline silicates electrolyte,however in varying concentration to explore the microstructure,chemical composition and subsequent effects on the biodegradation of the PEO coated Mg AZ91 alloy.From surface analysis-,carried out through SEM,samples with zero-(EDTA)^(4-)were found-,lacking pancake structural features;however,supplementing electrolyte with(EDTA)^(4-),bulky and layered pancakes were obtained with minimum cracks and minimum porosity for EDT-1.From the phase and inner layer analysis,it was found that EDTA can significantly alter the surface layers composition and could act as a passivation agent-;however,individual polycrystalline phases were not found to form.The hardness value obtained for EDT-1 was~909.69 HV,the highest value found here which occurs with the shallowest indents found in this study.In-vitro degradation analysis was carried out using potentiodynamic polarization at room temperature,cyclic polarization at RT and high fever conditions(HFT~40°C).The corrosion potential for coated AZ91 was obtained as a positive value of~0.1 V,for the first time in the PEO research;however,the results were not supported by the cyclic polarization tests at room temperature and at HFT.The post corrosion microstructural analysis confirmed the effective role of EDTA up to 1.0 g·L^(-1)and revealed the formation of thin films during the forward polarization at HFT.