Objective:The aim of this review was to identify the possible mechanisms behind cupping therapy by employing an evidence-based approach,and to explore its possible regional and systemic effects in the human body.Metho...Objective:The aim of this review was to identify the possible mechanisms behind cupping therapy by employing an evidence-based approach,and to explore its possible regional and systemic effects in the human body.Methods:We searched six electronic databases and four online trial registries for articles published up to January 1,2020.Clinical studies on the mechanisms of retained cupping,flashing cupping,moving cupping,and vacuum cupping were considered for this review.The methodological qualities of controlled studies were assessed using the National Institute for Clinical Excellence methodology checklist,the Newcastle-Ottawa Scale,and the Cochrane risk of bias tool.Characteristic statistical description and qualitative summary of results were used for data analysis.Results:Thirty-eight studies(37 full texts and one abstract)were included in this study.Due to the clinical heterogeneity among the studies,we could not conduct a meta-analysis.The results showed that the key factors that contribute to the efficacy of cupping therapy are negative pressure and temperature.Cupping therapy mainly causes local and systemic changes in hemodynamics,immune regulation,metabolism,and pain relief.Conclusion:We identified negative pressure as the key element behind cupping therapy.Cupping therapy may cause redistribution of oxygen at the cupping site and in neighboring tissues,thereby inducing a therapeutic effect by increasing regional blood flow.It may also induce metabolic change,immunomodulation,and neuromodulation.However,additional rigorous clinical research needs to be conducted to further clarify the mechanism behind cupping therapy.展开更多
The decline in birth rates has become a very serious problem in various parts of the world.Many countries have implemented national programs for increasing birth rates,one of which involves the use of traditional medi...The decline in birth rates has become a very serious problem in various parts of the world.Many countries have implemented national programs for increasing birth rates,one of which involves the use of traditional medicine as an alternative solution.Among the fast-growing traditional medicines,traditional Chinese medicine(TCM)and traditional Indonesian medicine(TIM)have attracted a lot of demand globally.Here,we analyzed and compared the herbal medicines from TCM and TIM that must be avoided by pregnant women for preventing miscarriage and maintaining safety during pregnancy and the postpartum period.This review uses data from official reports from the respective government and national and international electronic databases for analysis.Although TCM and TIM have their own characteristics of treatment,they also have some similarities in concept and treatment,especially those related to herbal medicines.This review can be used as a reference base to help pregnant women consume herbal medicines at appropriate conditions and doses.展开更多
Warburgia ugandensis(W.ugandensis)is known by various names,including the East African greenheart,pepper bark tree,and Ugandan greenheart,and has a rich history of extensive use in the treatment of a host of human dis...Warburgia ugandensis(W.ugandensis)is known by various names,including the East African greenheart,pepper bark tree,and Ugandan greenheart,and has a rich history of extensive use in the treatment of a host of human diseases in many African countries.This review is based on the botany and ethnopharmacological potentials of W.ugandensis for the treatment of pneumonia,asthma,malaria,candidiasis,skin infections,human immunodeficiency virus opportunistic infections,diarrhea,and measles given the common use in the management of these diseases.Extracts from W.ugandensis have strong antimicrobial activities against a broad spectrum of pathogens mainly because of the presence of abundant terpenoids,drimane,and coloratane type sesquditerpenoids amongst which are ugandensial,warburganal,mukaadial,and other secondary metabolites,such as tannins,flavonoids,saponins,steroids,and mannitol.This group of compounds gives the plant a high therapeutic value.Based on the review,there is a need for identification and isolation of the highly therapeutic phytochemical constituents and a drive for more preclinical and clinical trials to validate the safety and efficacy of the extracts.This gives basis for the potential development of new therapeutic drugs from the plant.展开更多
基金This review is supported by the National Natural Science Foundation of China(81804000)the National Natural Science Foundation of China:Major Program(81830115).
文摘Objective:The aim of this review was to identify the possible mechanisms behind cupping therapy by employing an evidence-based approach,and to explore its possible regional and systemic effects in the human body.Methods:We searched six electronic databases and four online trial registries for articles published up to January 1,2020.Clinical studies on the mechanisms of retained cupping,flashing cupping,moving cupping,and vacuum cupping were considered for this review.The methodological qualities of controlled studies were assessed using the National Institute for Clinical Excellence methodology checklist,the Newcastle-Ottawa Scale,and the Cochrane risk of bias tool.Characteristic statistical description and qualitative summary of results were used for data analysis.Results:Thirty-eight studies(37 full texts and one abstract)were included in this study.Due to the clinical heterogeneity among the studies,we could not conduct a meta-analysis.The results showed that the key factors that contribute to the efficacy of cupping therapy are negative pressure and temperature.Cupping therapy mainly causes local and systemic changes in hemodynamics,immune regulation,metabolism,and pain relief.Conclusion:We identified negative pressure as the key element behind cupping therapy.Cupping therapy may cause redistribution of oxygen at the cupping site and in neighboring tissues,thereby inducing a therapeutic effect by increasing regional blood flow.It may also induce metabolic change,immunomodulation,and neuromodulation.However,additional rigorous clinical research needs to be conducted to further clarify the mechanism behind cupping therapy.
基金Development of Sustainable Application for Standard Herbal Resources(No.KSN2012320)Reinforcing Clinical Evidence of Korean Medicine Health Technology(No.KSN2013210)Korea Institute of Oriental Medicine through the Ministry of Science and Information and Communication Technologies,Republic of Korea。
文摘The decline in birth rates has become a very serious problem in various parts of the world.Many countries have implemented national programs for increasing birth rates,one of which involves the use of traditional medicine as an alternative solution.Among the fast-growing traditional medicines,traditional Chinese medicine(TCM)and traditional Indonesian medicine(TIM)have attracted a lot of demand globally.Here,we analyzed and compared the herbal medicines from TCM and TIM that must be avoided by pregnant women for preventing miscarriage and maintaining safety during pregnancy and the postpartum period.This review uses data from official reports from the respective government and national and international electronic databases for analysis.Although TCM and TIM have their own characteristics of treatment,they also have some similarities in concept and treatment,especially those related to herbal medicines.This review can be used as a reference base to help pregnant women consume herbal medicines at appropriate conditions and doses.
基金Supported by the Framework of International Cooperation Program(Korea-South Africa Cooperative Research Project for Excavation of Candidate Resources of Complementary and Alternative Medicine)managed by National Research Foundation of Korea[No.2017093655,Korea Institute of Oriental Medicine(KIOM):D17470]Development of Foundational Techniques for the Domestic Production of Herbal Medicines(No.K18405)Applicational Development of Standardized Herbal Resources(KSN1911420)from KIOM,through the Ministry of Science and ICT,Republic of Korea。
文摘Warburgia ugandensis(W.ugandensis)is known by various names,including the East African greenheart,pepper bark tree,and Ugandan greenheart,and has a rich history of extensive use in the treatment of a host of human diseases in many African countries.This review is based on the botany and ethnopharmacological potentials of W.ugandensis for the treatment of pneumonia,asthma,malaria,candidiasis,skin infections,human immunodeficiency virus opportunistic infections,diarrhea,and measles given the common use in the management of these diseases.Extracts from W.ugandensis have strong antimicrobial activities against a broad spectrum of pathogens mainly because of the presence of abundant terpenoids,drimane,and coloratane type sesquditerpenoids amongst which are ugandensial,warburganal,mukaadial,and other secondary metabolites,such as tannins,flavonoids,saponins,steroids,and mannitol.This group of compounds gives the plant a high therapeutic value.Based on the review,there is a need for identification and isolation of the highly therapeutic phytochemical constituents and a drive for more preclinical and clinical trials to validate the safety and efficacy of the extracts.This gives basis for the potential development of new therapeutic drugs from the plant.
