Increasing evidence shows that the human brain is a highly self-organized system that shows attributes of smallworldness,hierarchy and modularity.The "connectome" was conceived several years ago to identify the unde...Increasing evidence shows that the human brain is a highly self-organized system that shows attributes of smallworldness,hierarchy and modularity.The "connectome" was conceived several years ago to identify the underpinning physical connectivities of brain networks.The need for an integration of multi-spatial and-temporal approaches is becoming apparent.Therefore,the "Brainnetome"(brain-net-ome) project was proposed.Diffusion magnetic resonance imaging(dMRI) is a non-invasive way to study the anatomy of brain networks.Here,we review the principles of dMRI,its methodologies,and some of its clinical applications for the Brainnetome.Future research in this field is discussed.展开更多
基金supported by the National Basic Research Development Program(973) of China(2011CB707800)the National Natural Science Foundation of China(91132301 and 81000634)
文摘Increasing evidence shows that the human brain is a highly self-organized system that shows attributes of smallworldness,hierarchy and modularity.The "connectome" was conceived several years ago to identify the underpinning physical connectivities of brain networks.The need for an integration of multi-spatial and-temporal approaches is becoming apparent.Therefore,the "Brainnetome"(brain-net-ome) project was proposed.Diffusion magnetic resonance imaging(dMRI) is a non-invasive way to study the anatomy of brain networks.Here,we review the principles of dMRI,its methodologies,and some of its clinical applications for the Brainnetome.Future research in this field is discussed.