期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Applications of integrative OMICs approaches to gene regulation studies 被引量:1
1
作者 Jing Qin Bin Yan +2 位作者 Yaohua Hu Panwen Wang Junwen Wang 《Frontiers of Electrical and Electronic Engineering in China》 CSCD 2016年第4期283-301,共19页
Functional genomics employs dozens of OMICs technologies to explore the functions of DNA, RNA and protein regulators in gene regulation processes. Despite each of these technologies being powerful tools on their own, ... Functional genomics employs dozens of OMICs technologies to explore the functions of DNA, RNA and protein regulators in gene regulation processes. Despite each of these technologies being powerful tools on their own, fike the parable of blind men and an elephant, any one single technology has a limited ability to depict the complex regulatory system. Integrative OMICS approaches have emerged and become an important area in biology and medicine. It provides a precise and effective way to study gene regulations. Results: This article reviews current popular OMICs technologies, OMICs data integration strategies, and bioinformatics tools used for multi-dimensional data integration. We highlight the advantages of these methods, particularly in elucidating molecular basis of biological regulatory mechanisms. Conclusions: To better understand the complexity of biological processes, we need powerful bioinformatics tools to integrate these OMICs data. Integrating multi-dimensional OMICs data will generate novel insights into system-level gene regulations and serves as a foundation for further hypothesis-driven research. 展开更多
关键词 gene regulatory networks integrative analysis OMICS ChlP-seq RNA-SEQ
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部