期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Mannan-binding lectin-associated serine protease-2 (MASP-2) deficiency in two patients with pulmonary tuberculosis and one healthy control 被引量:2
1
作者 Anna Sokolowska Agnieszka Szala +6 位作者 Anna St Swierzko Monika Kozinska Tomasz Niemiec Maria Blachnio Ewa Augustynowicz-Kopec Jaroslaw Dziadek Maciej Cedzynski 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2015年第1期119-121,共3页
Hereditary complement deficiencies are usually associated with increased susceptibility to infections and/ or autoimmune diseases. Generally, they are rare: the majority have been detected in no more than a few dozen... Hereditary complement deficiencies are usually associated with increased susceptibility to infections and/ or autoimmune diseases. Generally, they are rare: the majority have been detected in no more than a few dozen individuals. However, due to lack of population-based studies, such cases are usually detected by chance, e.g., in severely ill persons and their family members. An exception is mannan-binding lectin (MBL) deficiency, affecting perhaps 5%-10% of the population. MBL, like collectin-10, -11 and the ficolins (M-, L-, H-), is a pattern-recognition molecule, cooperating with MBL- associated serine proteases (MASPs) in the initiation of complement activation via the lectin pathway. In contrast, deficiency 展开更多
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部