A facile microwave-assisted synthesis of N-[(Z)-1-(substituted carbamoyl)-2-arylvinyl] benzamide derivatives is accomplished via reactions of 4-arylmethylene-2-phenyloxazol-5(4H)-ones with different amines (for...A facile microwave-assisted synthesis of N-[(Z)-1-(substituted carbamoyl)-2-arylvinyl] benzamide derivatives is accomplished via reactions of 4-arylmethylene-2-phenyloxazol-5(4H)-ones with different amines (for example me- thylamine, cyclopropylamine, para-toluidine, phenylarnine) in ethylene glycol. This protocol broadens the scope of the reaction for the synthesis of N-benzamide derivatives.展开更多
基金Project supported by the National Natural Science Foundation of China (No. 20672090), Natural Science Foundation of Jiangsu Province (No. BK2006033), and the Qing Lan Project of Jiangsu Province (No. 08QLT001).
文摘A facile microwave-assisted synthesis of N-[(Z)-1-(substituted carbamoyl)-2-arylvinyl] benzamide derivatives is accomplished via reactions of 4-arylmethylene-2-phenyloxazol-5(4H)-ones with different amines (for example me- thylamine, cyclopropylamine, para-toluidine, phenylarnine) in ethylene glycol. This protocol broadens the scope of the reaction for the synthesis of N-benzamide derivatives.