基金supported by FCT through the grants PD/BD/140202/2018,SFRH/BD/140191/2018 and SFRH/BD/128657/2017the projects PTDC/EMS-TEC/5422/2014 and NORTE-01-0145-FEDER-000018-HAMa BICo+1 种基金supported by FCT with the reference project UID/EEA/04436/2019the financial support through the M-ERA-NET/0001/2015 project(FCT)