To The Editor I want to congratulate Dr.Tan and colleagues for their article entitled'Weekly taxane-anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally adva...To The Editor I want to congratulate Dr.Tan and colleagues for their article entitled'Weekly taxane-anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer:a randomized controlled trial'[1].The pathologic complete response(pCR)rate was similar in the two arms(10.61%vs.12.31%,P=0.665).However,the展开更多
To The Editor,I want to congratulate Jin and colleagues for their article entitled “ABO blood group is a predictor of survival in patients with laryngeal cancer” recently reported in Chinese Journal of Cancer, in wh...To The Editor,I want to congratulate Jin and colleagues for their article entitled “ABO blood group is a predictor of survival in patients with laryngeal cancer” recently reported in Chinese Journal of Cancer, in which they assessed whether the ABO blood group was associated with prognosis in patients with laryngeal cancer [1]. They reported that compared with the patients with blood group non-O,patients with blood group O had significantly shorter OS.However, there is no satisfactory explanation why laryngeal cancer patients with blood group O had shorter OS.Blood group antigens are expressed on the surface of red blood cells and numerous other tissues throughout the body, including different types of cancer cells as well [2].These A or B antigens located on laryngeal cancer cell surface may be recognized from the immune system as antigenic foci. Hence, laryngeal cancer cells carrying A or B or both antigens could be destroyed by the immune system. On the other hand, laryngeal cancer cells harboring neither A nor B antigens, so-called type O cancer cells may not be recognized by immune cells and therefore may escape from immune destruction.展开更多
文摘To The Editor I want to congratulate Dr.Tan and colleagues for their article entitled'Weekly taxane-anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer:a randomized controlled trial'[1].The pathologic complete response(pCR)rate was similar in the two arms(10.61%vs.12.31%,P=0.665).However,the
文摘To The Editor,I want to congratulate Jin and colleagues for their article entitled “ABO blood group is a predictor of survival in patients with laryngeal cancer” recently reported in Chinese Journal of Cancer, in which they assessed whether the ABO blood group was associated with prognosis in patients with laryngeal cancer [1]. They reported that compared with the patients with blood group non-O,patients with blood group O had significantly shorter OS.However, there is no satisfactory explanation why laryngeal cancer patients with blood group O had shorter OS.Blood group antigens are expressed on the surface of red blood cells and numerous other tissues throughout the body, including different types of cancer cells as well [2].These A or B antigens located on laryngeal cancer cell surface may be recognized from the immune system as antigenic foci. Hence, laryngeal cancer cells carrying A or B or both antigens could be destroyed by the immune system. On the other hand, laryngeal cancer cells harboring neither A nor B antigens, so-called type O cancer cells may not be recognized by immune cells and therefore may escape from immune destruction.
