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Nutraceuticals as potential therapeutic agents for colon cancer: a review 被引量:4
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作者 Palaniselvam Kuppusamy Mashitah M.Yusoff +3 位作者 Gaanty Pragas Maniam Solachuddin Jauhari Arief Ichwan Ilavenil Soundharrajan Natanamurugaraj Govindan 《Acta Pharmaceutica Sinica B》 SCIE CAS 2014年第3期173-181,共9页
Colon cancer is a world-wide health problem and the second-most dangerous type of cancer,affecting both men and women.The modern diet and lifestyles,with high meat consumption and excessive alcohol use,along with limi... Colon cancer is a world-wide health problem and the second-most dangerous type of cancer,affecting both men and women.The modern diet and lifestyles,with high meat consumption and excessive alcohol use,along with limited physical activity has led to an increasing mortality rate for colon cancer worldwide.As a result,there is a need to develop novel and environmentally benign drug therapies for colon cancer.Currently,nutraceuticals play an increasingly important role in the treatment of various chronic diseases such as colon cancer,diabetes and Alzheimer's disease.Nutraceuticals are derived from various natural sources such as medicinal plants,marine organisms,vegetables and fruits.Nutraceuticals have shown the potential to reduce the risk of colon cancer and slow its progression.These dietary substances target different molecular aspects of colon cancer development.Accordingly,this review briefly discusses the medicinal importance of nutraceuticals and their ability to reduce the risk of colorectal carcinogenesis. 展开更多
关键词 Colon cancer NUTRACEUTICALS THERAPEUTICS Marine organisms Plant derivatives
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Induction of bioactive compound composition from marine microalgae(Lyngbya sp.)by using different stress condition
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作者 Nurul Farhana Rosly Rabeah Adawiyah Abdul Razak +2 位作者 Palaniselvam Kuppusamy Mashitah M.Yusoff Natanamurugaraj Govindan 《Journal of Coastal Life Medicine》 2013年第3期205-209,共5页
Objective:To the effect of salinity stress on the production of microalgae(Lyngbya sp.)and chlorophyll pigments in the growth medium.Methods:Stress was investigated by using green algae strains Lyngbya sp.in response ... Objective:To the effect of salinity stress on the production of microalgae(Lyngbya sp.)and chlorophyll pigments in the growth medium.Methods:Stress was investigated by using green algae strains Lyngbya sp.in response to change bioactive compounds without any modification of cell growth and biomass production rate.The different stress conditions like 10%-40%were analyzed.Results:During the stress condition,various biochemical and microbiological assays were monitored.The photochemical composition was evaluated by GC-MS studies.The studies expressed that 30%higher salinity stress was suitable for high phytochemical production rate including chlorophyll content.Conclusions:Our study indicates the wide range of salinity stress to enhance the growth on microalgae culture and enhance the production of major secondary metabolites. 展开更多
关键词 Lyngbya Sp. Salinity stress Secondary metabolites BIOMASS CHLOROPHYLL
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