In recent years,the clustered regularly interspaced short palindromic repeats-associated protein 9(CRISPR-Cas9)technology that won the 2020 Nobel Prize in Chemistry has served as one of the most prominent and powerful...In recent years,the clustered regularly interspaced short palindromic repeats-associated protein 9(CRISPR-Cas9)technology that won the 2020 Nobel Prize in Chemistry has served as one of the most prominent and powerful tools in gene editing for biomedical research and the treatment of various diseases[1].Nevertheless,it remains a substantial challenge to effectively and safely deliver CRISPR-Cas9 molecules into target cells[2].展开更多
The global population is projected to reach 9.7 billion in 2050,companying with increasing food demand and rising bioenergy consumption,thus the global biomass production is expected to increase by up to 60%relative t...The global population is projected to reach 9.7 billion in 2050,companying with increasing food demand and rising bioenergy consumption,thus the global biomass production is expected to increase by up to 60%relative to the level in 2005[1,2].In sharp contrast,the acreage of agricultural land has been stagnant and even shrunk for a long time.Any expansion will happen mostly at the expense of habitat loss and threaten biological diversity.展开更多
基金supported by the National Key R&D Program of China(2016YFA0203700)the National Natural Science Foundation of China(51672303,81902315,82102085,32101146)+3 种基金Excellent Talents Nurture Project of Shanghai Chest Hospital(2021YNZYY02)International Collaboration Project of Chinese Academy of Sciences(GJHZ2072)financial support from Science and Technology Development Fund of Shanghai Chest Hospitalfinancial support from Talent Training Plan of Shanghai Chest Hospital in 2020。
文摘In recent years,the clustered regularly interspaced short palindromic repeats-associated protein 9(CRISPR-Cas9)technology that won the 2020 Nobel Prize in Chemistry has served as one of the most prominent and powerful tools in gene editing for biomedical research and the treatment of various diseases[1].Nevertheless,it remains a substantial challenge to effectively and safely deliver CRISPR-Cas9 molecules into target cells[2].
基金supported by the National Key R&D Program of China(2016YFA0203700)National Science Foundation for Young Scientists of China(51802336)the National Natural Science Foundation of China(51672303,51722211,and 52072393)。
文摘The global population is projected to reach 9.7 billion in 2050,companying with increasing food demand and rising bioenergy consumption,thus the global biomass production is expected to increase by up to 60%relative to the level in 2005[1,2].In sharp contrast,the acreage of agricultural land has been stagnant and even shrunk for a long time.Any expansion will happen mostly at the expense of habitat loss and threaten biological diversity.
