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Stem cell differentiation and human liver disease 被引量:3
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作者 Wen-Li Zhou Claire N Medine +1 位作者 Liang Zhu David C Hay 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第17期2018-2025,共8页
Human stem cells are scalable cell populations capable of cellular differentiation.This makes them a very attractive in vitro cellular resource and in theory provides unlimited amounts of primary cells.Such an approac... Human stem cells are scalable cell populations capable of cellular differentiation.This makes them a very attractive in vitro cellular resource and in theory provides unlimited amounts of primary cells.Such an approach has the potential to improve our understanding of human biology and treating disease.In the future it may be possible to deploy novel stem cell-based approaches to treat human liver diseases.In recent years,eff icient hepatic differentiation from human stem cells has been achieved by several research groups including our own.In this review we provide an overview of the f ield and discuss the future potential and limitations of stem cell technology. 展开更多
关键词 Differentiation Pluripotent stem cells Hepatocyte-like cells Liver development Polymer chemistry Regenerative medicine Transplantation Bio-artif icial liver
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