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Purification and Characterization of an Antibacterial Peptide from Rana Temporaria Chensinensis Skin 被引量:2
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作者 GOU Xiao-jun LI Xiang-hui +7 位作者 DING Tian-bing WANG Yong-ting CHEN Huai-yong HUANG Cheng-fang DONG Qing-chu LI Qing-shan WANG Yan-zhong ZHAO Lu-lu 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1999年第4期333-336,共4页
The Rana temporaria chensinensis is an amphibian distributing mainly over the north of China. Its skin gland contains a variety of peptides, including antibacterial peptides. One of them, component 1, has been pur... The Rana temporaria chensinensis is an amphibian distributing mainly over the north of China. Its skin gland contains a variety of peptides, including antibacterial peptides. One of them, component 1, has been purified from the dried skin of R.temporaria chensinesis using a five step procedure. Purified component 1 has a molecular weight of 5 700 and its amino acid composition shows that it is devoid of disulfide bridges but rich in histine and glycine residues. Moreover, it has been found that it has a broad spectrum of antibacterial activity for Pseuctomonas aeruginosa, Escherichia coli, Bacillus sublilis, S. faccalis and Proteus vulgaris . 展开更多
关键词 Antibacterial activity PEPTIDE Dried skin
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