Although the diagnosis of type 2 diabetes mellitus was once considered a contraindication to simultaneous pancreas-kidney transplantation, a growing body of evidence has revealed that similar graft and patient surviva...Although the diagnosis of type 2 diabetes mellitus was once considered a contraindication to simultaneous pancreas-kidney transplantation, a growing body of evidence has revealed that similar graft and patient survival can be achieved when compared to type 1 diabetes mellitus recipients. A cautious strategy regarding candidate selection may limit appropriate candidates from additional benefits in terms of quality of life and potential amelioration of secondary side effects of the disease process. Although our current understanding of the disease has changed, uniform listing characteristics to better define and study this population have limited available data and must be established.展开更多
Total pancreatectomy and islet auto transplantation is a good option for chronic pancreatitis patients who suffer from significant pain, poor quality of life, and the potential of type 3C diabetes and pancreatic cance...Total pancreatectomy and islet auto transplantation is a good option for chronic pancreatitis patients who suffer from significant pain, poor quality of life, and the potential of type 3C diabetes and pancreatic cancer. Portal vein thrombosis is the most feared complication of the surgery and chances are increased if the patient has a hypercoagulable disorder. We present a challenging case of islet auto transplantation from our institution. A 29-year-old woman with plasminogen activator inhibitor-4G/4G variant and a clinical history of venous thrombosis was successfully managed with a precise peri- and postoperative anticoagulation protocol. In this paper we discuss the anti-coagulation protocol for safely and successfully caring out islet transplantation and associated risks and benefits.展开更多
A renal paratransplant hernia is an unusual and potentially serious variant of an internal hernia. It is caused by entrapment of bowel through a defect in the peritoneum adjacent to the transplanted kidney. Abdominal ...A renal paratransplant hernia is an unusual and potentially serious variant of an internal hernia. It is caused by entrapment of bowel through a defect in the peritoneum adjacent to the transplanted kidney. Abdominal pain and vomiting with or without distention are the main symptoms. Prompt diagnosis and early surgical intervention are critical to prevent serious morbidity and even mortality. Historically, renal paratransplant hernias were repaired via an exploratory laparotomy. We present our experience in two patients with renal paratransplant hernia who were treated with laparoscopic repair.展开更多
文摘Although the diagnosis of type 2 diabetes mellitus was once considered a contraindication to simultaneous pancreas-kidney transplantation, a growing body of evidence has revealed that similar graft and patient survival can be achieved when compared to type 1 diabetes mellitus recipients. A cautious strategy regarding candidate selection may limit appropriate candidates from additional benefits in terms of quality of life and potential amelioration of secondary side effects of the disease process. Although our current understanding of the disease has changed, uniform listing characteristics to better define and study this population have limited available data and must be established.
文摘Total pancreatectomy and islet auto transplantation is a good option for chronic pancreatitis patients who suffer from significant pain, poor quality of life, and the potential of type 3C diabetes and pancreatic cancer. Portal vein thrombosis is the most feared complication of the surgery and chances are increased if the patient has a hypercoagulable disorder. We present a challenging case of islet auto transplantation from our institution. A 29-year-old woman with plasminogen activator inhibitor-4G/4G variant and a clinical history of venous thrombosis was successfully managed with a precise peri- and postoperative anticoagulation protocol. In this paper we discuss the anti-coagulation protocol for safely and successfully caring out islet transplantation and associated risks and benefits.
文摘A renal paratransplant hernia is an unusual and potentially serious variant of an internal hernia. It is caused by entrapment of bowel through a defect in the peritoneum adjacent to the transplanted kidney. Abdominal pain and vomiting with or without distention are the main symptoms. Prompt diagnosis and early surgical intervention are critical to prevent serious morbidity and even mortality. Historically, renal paratransplant hernias were repaired via an exploratory laparotomy. We present our experience in two patients with renal paratransplant hernia who were treated with laparoscopic repair.
