肝泡状棘球蚴病:临床、影像学检查特点和内窥镜检查

Hepatic alveolar echinococcosis is a rare but potentially life threatening serious parasitic disease, developing as a result of intrahepatic growth of Echinococcus multilocularis larvae. It may present as an invasive mass causing biliary obstruction or portal hypertension due to invasion of the biliary and vascular structure of the liver. The only curative treatment of the disease is surgical resection; however, early diagnosis is the key point to achieve complete cure. In advanced disease, complications are common. We retrospectively analyzed 12 cases of hepatic alveolar echinococcosis and reviewed the relevant literature. A high index of suspicion and specific radiologic findings are very helpful in the diagnosis of the disease. While benzimidazole derivatives are used for the control of disease, endoscopic retrograde cholangiopancreatography is particularly effective in the biliary involvement, even in the late stage of disease.

Petrology of ultramafic to mafic cumulate rocks from the G?ksun(Kahramanmaras) ophiolite,southeast Turkey

The G?ksun(Kahramanmaras)ophiolite(GKO),cropping out in a tectonic window bounded by the Malatya metamorphic unit on both the north and south,is located in the EW-trending lower nappe zone of the southeast Anatolian orogenic belt(Turkey).It exhibits a complete oceanic lithospheric section and overlies the Middle Eocene Maden Group/Complex with a tectonic contact at its base.The ophiolitic rocks and the tectonically overlying Malatya metamorphic(continental)unit were intruded by I-type calc-alkaline Late Cretaceous granitoid(~81-84 Ma).The ultramafic to cumulates in the GKO are represented by wehrlite,plagioclase wehrlite,olivine gabbro and gabbro.The crystallization order for the cumulate rocks is as follows:olivine±chromian spinel→clinopyroxene→plagioclase.The major and trace element geochemistry as well as the mineral chemistry of the ultramafic to mafic cumulate rocks suggest that the primary magma generating the GKO is compositionally similar to that observed in the modern island-arc tholeiitic sequences.The mineral chemistry of the ultramafic to mafic cumulates indicates that they were derived from a mantle source that was previously depleted by earlier partial melting events.The highly magnesian olivine(Fo77-83),clinopyroxene(Mg#of 82-90)and the highly Ca-plagioclase(An81-89)exhibit a close similarity to those,which formed in a supra-subduction zone(SSZ)setting.The field and the geochemical evidence suggest that the GKO formed as part of a much larger sheet of oceanic lithosphere,which accreted to the base of the Tauride active continental margin,including the ispendere,K?mürhan and the Guleman ophiolites.The latter were contemporaneous and genetically/tectonically related within the same SSZ setting during the closure of the Neotethyan oceanic basin(Berit Ocean)between the Taurides to the north and the Bitlis-Pütürge massif to the south during the Late Cretaceous.

白塞病患者载脂蛋白E多态性和脂蛋白成分

Background. Behc.et’s disease (BD) is a multisystemic disease of unknown etio logy characterized by chronic relapsing oral-genital ulcers and uveitis. Some a bnormalities in lipoprotein metabolism have been described in patients with BD. Methods. In this study, apolipoprotein E (apo E) polymorphism and lipoprotein ch olesterol concentrations in 30 patients with BD were compared with those of 27 c ontrol subjects. Results. Both patients and controls were found to be normolipid emic. Patients with BD had significantly higher concentrations of high-density lipoprotein (HDL) cholesterol than those of controls (P < .0.05); however, there was no difference in serum triglyceride, low-densitylipoprotein(LDL)and very l ow-density lipoprotein (VLDL) cholesterol concentrations. The distribution of a po E genotypes and alleles was the same in both groups. There were slight differ ences in allele frequency between the groups, but this was not statistically sig nificant. Conclusions. The high HDL cholesterol levels observed in our patients were not related to abnormalities in apo E alleles.

圆形切除面部良性小丘疹圆顶形黑色素细胞痣

Background. Patients frequently request the removal of benign, papular and dome-shaped nevi for cosmetic or functional reasons. Total excision is probably the most widely used method of removal. Aim. To introduce the round excision technique for the treatment of benign, papular and dome-shaped nevi on the face. Methods. In a prospective study, 36 benign, papular or dome-shaped nevi of all types were removed by the round excision technique. The lesions were circumscribed with a number 15 scalpel blade, 2 mm beyond the limits, with incision to the full depth of the dermis, and removed by cutting horizontally at the maximum depth of the circular incision. Histologic examinations were performed for all specimens. Results. Complete removal of nevi was achieved in all patients with excellent or good cosmetic results. Of the 36 nevi, 24 were intradermal and 12 were compound nevi. Dog-ear formation was observed in only one patient. Conclusion. Round excision may be a better alternative to conventional fusiformor shaveexcision of benign, dome-shaped or papular nevi of the face.

氧化应激酶在开角型青光眼患者中的作用

Purpose: To investigate the role of oxidative stress and lipid peroxidation in the pathogenesis of primary open-angle glaucoma (POAG). Materials and methods: The activities of myeloperoxidase (MPO), catalase (CAT), and the levels of plasma malondialdehyde (MDA) were measured in 40 (15 men and 25 women) patients with POAG and 60 (30 men and 30 women)-healthy controls. Results: Therewas no significant difference in the activities of CAT andMPO between the POAG patients and the controls. However, the plasmaMDA level was significantly higher in patients than the controls. Conclusion: The results of this preliminary study suggest that the possible alterations of plasmaMDA levels may be associated with the pathogenesis of POAG, but further research is needed to understand the role of oxidative damage in this important disorder of aging.