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Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition
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作者 Mahboubeh Ahmadi Nahid Rouhi +1 位作者 Javad Mirnajafi-Zadeh Bechara J.Saab 《Neural Regeneration Research》 SCIE CAS 2025年第11期3225-3226,共2页
Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain processes.While dopamine is primarily associated with pleasure,reward,and motivation,... Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain processes.While dopamine is primarily associated with pleasure,reward,and motivation,its effects can be quite complex;and this complexity is further compounded when examining how dopamine functions in typical versus disease-affected neural circuits.In pa rticula r,epilepsy,characte rized by heightened brain excitability,is linked to cognitive dysfunction,and dopamine is implicated in elements of both its pathology and treatment.Neuroscience has been successful in describing the synaptic abnormalities believed to contribute to memory issues in epilepsy,aiding in the search for effective therapies for what persists as a major medical issue. 展开更多
关键词 DOPAMINE EPILEPSY primarily
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